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Xenobiotica
the fate of foreign compounds in biological systems
Volume 25, 1995 - Issue 8
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Research Article

Biliary metabolites of semotiadil fumarate in the rat

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Pages 847-855 | Received 06 Mar 1995, Published online: 22 Sep 2008

References

  • Fujita M., Ito S., Ota A., Kato N., Yamamoto K., Kawashima Y., Yamauchi H., Iwao J. Synthesis and Ca2+ antagonistic activity of 2-[2-[(aminoalkyl)oxy]-5-methoxyphenyl]-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzothiazines. Journal of Medicinal Chemistry 1990; 33: 1898–1905
  • Kumagai Y., Wickham K. A., Schmitz D. A., Cho A. K. Metabolism of methylenedioxyphenyl compounds by rabbit liver preparations. Biochemical Pharmacology 1991; 42: 1061–1067
  • Morikawa N., Takashina H., Ibuki H., Matsuoka H., Yamaguchi H., Miyagi S., Horiuchi M. Studies on the metabolic fate of semotiadil fumarate (SD-3211) (I): absorption, distribution, metabolism and excretion after single administration to male rats. Xenobiotic Metabolism and Disposition 1992; 7: 315–330
  • Zhang K., Lepage F., Cuvier G., Astoin J., Rashed M. S., Baillie T. A. The metabolic fate of stiripentol in the rat. Drug Metabolism and Disposition 1990; 18: 794–803

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