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Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 1
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Research Article

Characterization of in vitro metabolites from human liver microsomes using directly coupled hplc-nmr: application to a phenoxathiin monoamine oxidase-A inhibitor

J. P. Shockcor Wellcome Research Laboratories, Research Triangle Park, NC 27706, USA
,
I. S. Silver Wellcome Research Laboratories, Research Triangle Park, NC 27706, USA
,
R. M. Wurm Wellcome Research Laboratories, Research Triangle Park, NC 27706, USA
,
P. N. Sanderson Department of Physical Sciences, Wellcome Research Laboratories, Langley Court, Beckenham BR3 3BS, UK
,
R. D. Farrant Department of Physical Sciences, Wellcome Research Laboratories, Langley Court, Beckenham BR3 3BS, UK
,
B. C. Sweatman Department of Physical Sciences, Wellcome Research Laboratories, Langley Court, Beckenham BR3 3BS, UK
&
J. C. Lindon Department of Physical Sciences, Wellcome Research Laboratories, Langley Court, Beckenham BR3 3BS, UK
 show all
Pages 41-48 | Published online: 17 Nov 2010

References

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  • SWEATMAN, B. C., TARRANT, R. D., SANDERSON, P. N., PHILIPPE, I., SALMAN, S. R., NICHOLSON, J. K., and LINDON, J. C., 1995. Evaluation of the detection limits of directly coupled 600 MHz 'H and "H-13C HPLC-NMR spectroscopy. Journal of Magnetic Resonance Anakvsis, 1, 9–12.
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