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Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 2
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Research Article

Identification of trimetazidine metabolites in human urine and plasma

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Pages 221-228 | Received 13 Jul 1995, Published online: 22 Sep 2008

References

  • Maridonneau-Parini I., Harpey C. Effect of trimetazidine on membrane damage induced by oxygen free radicals in human red cells. British Journal Clinical Pharmacology 1985; 20: 148–151
  • Miyamoto G., Sasabe H., Tominaga N., Uegaki N., Tominaga M., Shimizu T. Metabolism of a new inotropic agent, 3,4-dihydro-6-[3,4-dimethoxybenzoyl)-1-piperazinyl]-2-(1H)-quinolinone (OPC-8212) in the rat mouse, dog, monkey, and human. Xenobiotica 1988; 18: 1143–1155
  • Sellier P., Audouin P., Payen B., Corona P., Duong T. C., Ourbak P. Acute effects of trimetazidine evaluated by exercise testing. European Journal Clinical Pharmacology 1987; 33: 205–207
  • Taylor A., Wood S., Patel S., Campbell D. The metabolism and kinetics of trimetazidine in human volunteers. Servier Research and Development Internal Document. 1982
  • Wallace D., Breen M., Brownsill R. D., Taylor A. R. The metabolism of trimetazidine in man. Servier Research and Development Internal Document. 1991

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