Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 4
51
Views
17
CrossRef citations to date
0
Altmetric
Research Article

Pharmacokinetics and metabolism of zamifenacin in mouse, rat, dog and man

, , &
Pages 459-471 | Received 05 Aug 1995, Published online: 22 Sep 2008

References

  • Anders M. W., Sunram J. M. Mechanism of the metabolism of 1,3-benzodioxoles to carbon monoxide. Biochemical Pharmacology 1983; 33: 577–580
  • Beaumont K. C., Macrae P. V., Miller C. M., Wright P. A., Smith D. A. Pharmacokinetics of zamifenazin in man and animals: species differences in plasma protein binding. British Journal of Clinical Pharmacology 1994; 38: 179
  • Haddock R. E., Johnson A. M., Langley P. F., Nelson D. R., Pope J. A., Thomas D. R., Woods F. R. Metabolic pathway of paroxetine in animals and man and the comparative pharmacological profile of its metabolites. Acta Psychiatrica Scandinavica 1989; 80(suppl. 350)24–26
  • Kamienski F. X., Casida J. E. Importance of demethylenation in the metabolism in vivo and in vitro of methylenedioxyphenyl synergists and related compounds in mammals. Biochemical Pharmacology 1970; 19: 91–112
  • Kaye C. M., Haddock R. E., Langley P. F., Mellows G., Tasker T. C. G., Zussman B. D., Greb W. H. A review of the metabolism and pharmacokinetics of paroxetine in man. Acta Psychiatrica Scandinavica 1989; 80(suppl. 350)60–75
  • Moreland T. A., Astoin J., Lepage F., Tombret F., Levy R. H., Baillie T. A. The metabolic rate of stiripentol in man. Drug Metabolism and Disposition 1986; 14: 654–662
  • Scheline R. R. Metabolism of foreign compounds by gastrointestinal microorganisms. Pharmacological Reviews 1973; 25: 451–523
  • Smith D. A. Aromatic hydroxylation of arylalkylamines in rodents. Drug Metabolism Reviews 1991; 23: 255
  • Wallis R. M., Alker D. A., Burges R. A., Cross P. E., Newgreen D. T., Quinn P. Zamifenacin: a novel gut-selective muscarinic receptor antagonist. British Journal of Pharmacology 1993; 109: 36

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.