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Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 7
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Research Article

Quantitation of cytochrome P450 enzymes (CYP1A1/2, 2B11, 2C21 and 3A12) in dog liver microsomes by enzyme-linked immunosorbent assay

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Pages 755-763 | Received 12 Dec 1995, Published online: 22 Sep 2008

References

  • Bandiera S., Ryan D. E., Levin W., Thomas P. E. Age- and sex-related expression of cytochrome P450f and P450g in rat liver. Archives of Biochemistry and Biophysics 1986; 248: 658–676
  • Bensoussan C., Delaforge M., Mansuy D. Particular ability of cytochromes P450 3A to form inhibitory P450-ion-metabolite complexes upon metabolic oxidation of aminodrugs. Biochemical Pharmacology 1995; 49: 591–602
  • Burke M. D., Thompson S., Elcombe C. R., Halpert J., Haaparanta T., Mayer R. T. Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P450. Biochemical Pharmacology 1985; 34: 3337–3345
  • Burke M. D., Thompson S., Weaver R. J., Wolf C. R., Mayer R. T. Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver. Biochemical Pharmacology 1994; 48: 923–936
  • Ciaccio P. J., Halpert J. Characterization of a phenobarbital-inducible dog liver cytochrome P450 structurally related to rat and human enzymes of the P450 IIIA (steroid-inducible) gene subfamily. Archives of Biochemistry and Biophysics 1989; 271: 284–299
  • Daujat M., Pichard L., Fabre I., Pineau T., Fabre G., Bonfils C., Maurel P. Induction protocols for cytochrome P450IIIA in vivo and in primary cultures of animal and human hepatocytes. Methods in Enzymology 1991; 206: 345–353
  • Halpert J. R., Guengerich F. R., Bend J. R., Correia M. A. Selective inhibitors of cytochrome P450. Toxicology and Applied Pharmacology 1994; 125: 163–175
  • Herrero M. E., Castell J. V. Quantification of CYP1A1 and 2B1/2 in rat hepatocytes cultured in microwells by immunological methods. Toxicology in Vitro 1994; 8: 1167–1175
  • Kaminsky L. S., Fasco M. J., Guengerich F. P. Production and application of antibodies to rat liver cytochrome P-450. Methods in Enzymology 1981; 74: 262–272
  • Komori M., Shimada H., Miura T., Kamataki T. Interspecies homology of liver microsomal cytochrome P-450. A form of dog cytochrome P-450 (P450-D1) crossreactive with antibodies to rat P-450-male. Biochemical Pharmacology 1989; 38: 235–240
  • Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J. Protein measurement with folin phenol reagent. Journal of Biological Chemistry 1951; 193: 265–275
  • Matsubara T., Otsubo S., Yoshihara E., Touchi A. Biotransformation of coumarin derivatives (2) oxidative metabolism of 7-alkoxyccumarin by microsomal enzymes and simple assay procedure for 7-alkoxycoumarin O-dealkylase. Japanese Journal of Pharmacology 1983; 33: 41–56
  • Nedelcheva V., Gut I. P450 in the rat and man: methods of investigation, substrate specificities and relevance to cancer. Xenobiotica 1994; 24: 1151–1175
  • Nelson D. R., Kamataki T., Waxman D. J., Guengerich F. P., Estabrook R. W., Feyereisen R., Gonzalez F. J., Coon M. J., Gunsalus I. C., Gotoh O., Okuda K., Nebert D. W. The P450 superfamily: update on new sequences, gene mapping, accession number, early trivial names of enzymes and nomenclature. DNA and Cell Biology 1993; 12: 1–51
  • Nishibe Y., Hirata M. Effect of phenobarbital and other model inducers on cytochrome P450 isoenzymes in primary culture of dog hepatocytes. Xenobiotica 1993; 23: 681–692
  • Nishibe Y., Hirata M. Induction of cytochrome P450 3A (CYP 3A) by E5110, a non-steroidal anti-inflammatory agent (NSAID), and typical CYP 3A inducers in primary culture of dog hepatocytes. Biological and Pharmaceutical Bulletin 1995; 18: 1142–1144
  • Ohta K., Motoya M., Komori M., Miura T., Kitada M., Kamataki T. A novel form of cytochrome P-450 in beagle dogs: P-450-D3 is a low spin form of cytochrome P-450 but with catalytic and structural properties similar to P-450d. Biochemical Pharmacology 1989; 38: 91–96
  • Ohta K., Motoya M., Komori M., Miura T., Kitada M., Nagao M., Kamataki T. Interspecies homology of cytochrome P-450: Purification and toxicological significance of a high spin form of cytochrome P-450 (P-450-D2) from liver microsomes of polychlorinated biphenyl (PCB)-treated beagle dogs. Journal of Biopharmaceutical Sciences 1990; 1: 59–71
  • Omura T., Sato R. The carbon monoxide-binding pigment of liver microsomes. Journal of Biological Chemistry 1964; 239: 2370–2378
  • Parke B. K., Breckenridge A. M. Clinical implications of enzyme induction and enzyme inhibition. Clinical Pharmacokinetics 1981; 6: 1–24
  • Pessayre D., Descatoire V., Konstantinova Mitcheva M. K., Wandscheer J. C., Cobert B., Level R., Benhamou J. P., Jaouen M., Mansuy D. Self induction by tri-acetyleandomycin of its own transformation into a metabolic forming a stable 456 nm-absorbing complex with cytochrome P-450. Biochemical Pharmacology 1981; 30: 553–558
  • Platt K. L., Molitor E., Döhmer J., Dogra S., Oesch F. Genetically engineered V79 chinese hamster cell expression of purified cytochrome P-450 IIB1 monooxygenase activity. Journal of Biochemical Toxicology 1989; 4: 1–6
  • Sakamoto K., Kirita S., Baba T., Nakamura Y., Yamazoe Y., Kato R., Takanaka A., Matsubara T. A new cytochrome P450 form belonging to the CYP2D in dog liver microsomes: purification, cDNA cloning, and enzyme characterization. Archives of Biochemistry and Biophysics 1995; 319: 372–382
  • Seidel S. L., Shawver L. K., Shires T. K. Detection of phenobarbital-induced cytochrome P450 in rat hepatic microsomes using an enzyme-linked immunosorbent assay. Archives of Biochemistry and Biophysics 1984; 229: 519–531
  • Shiraga T., Iwasaki K., Nozaki K., Tamura T., Yamazoe Y., Kato R., Takanaka A. Isolation and characterization of four cytochrome P450 isozymes from untreated and pheno-barbital-treated beagle dogs. Biological and Pharmaceutical Bulletin 1994; 17: 22–28
  • Tassaneeyakul W., Birkett D. J., McManus M. E., Tassaneeyakul W., Veronese M. E., Anderson T., Tukey R. H., Miners J. O. Caffeine metabolism by human hepatic cytochrome P450: contribution of 1A2, 2E1 and 3A isoforms. Biochemical Pharmacology 1994; 47: 1767–1776
  • Venkatesan K. Pharmacokinetic drug interactions with rifampicin. Clinical Pharmacokinetics 1992; 22: 47–65

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