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Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 8
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Research Article

Interspecies scaling of tolcapone, a new inhibitor of catechol-O-methyltransferase (COMT). Use of in vitro data from hepatocytes to predict metabolic clearance in animals and humans

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Pages 839-851 | Received 14 Feb 1996, Published online: 22 Sep 2008

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