Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 26, 1996 - Issue 12
28
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10

, , , , , & show all
Pages 1231-1239 | Received 10 Jun 1996, Published online: 22 Sep 2008

References

  • Back D. J., Tjia J. F., Karbwang J., Colbert J. In vitro inhibition studies of tolbutamide hydroxylase activity of human liver microsomes by azoles, sulphonamides and quinolines. British Journal of Clinical Pharmacology 1988; 26: 23–29
  • Brian W. R., Srivastava P. K., Umbenhauer D. R., Lloyd R. S., Guengerich F. P. Expression of a human liver cytochrome P450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae. Biochemstry 1989; 28: 4993–4999
  • Crespi C. L., Gonzalez F. J., Steimel D. T., Turner T. R., Gelboin H. V., Penman B. W., Langenbach R. A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing. Chemical Research in Toxicology 1991a; 4: 566–572
  • Crespi C. L., Penman B. W., Steimel D. T., Gelboin H. V., Gonzalez F. J. The development of a human cell line stably expressing human CYP3A4: role in the metabolic activation of aflatoxin and comparison to CYP1A2 and CYP2A3. Carcinogenesis 1991b; 12: 355–359
  • De Groene E. M., Seinen W., Horbach G. J. M. J. A NIH/3T3 cell line stably expressing human cytochrome P450–3A4 used in combination with a lacZ' shuttle vector to study mutagenicity. European Journal of Pharmacology 1995; 293: 47–53
  • De Groene E. M., Hassing I. G. A. M., Blom M. J., Seinen W., Fink-Gremmels J., Horbach G. J. Development of human cytochrome P450-expressing cell lines: application in mutagenicity testing of ochratoxin A. Cancer Research 1996; 56: 299–304
  • Denizat F., Lang R. Rapid colorimetric assay for cell growth and survival. Journal of Immunological Methods 1986; 89: 271–277
  • Doehmer J., Dogra S., Friedberg T., Monier S., Adesnik M., Glatt H., Oesch F. Stable expression of rat cytochrome P-450IIB1 cDNA in Chinese hamster cells (V79) and metabolic activation of aflatoxin B1. Proceedings of the National Academy of Sciences, USA 1988; 85: 5769–5773
  • Dogra S., Doehmer J., Glatt H., Molders H., Siegert P., Friedberg T., Seidei A., Oesch F. Stable expression of rat cytochrome P-450IA1 cDNA in V79 Chinese hamster cells and their use in mutagenicity testing. Molecular Pharmacology 1990; 37: 608–613
  • Ged C., Umbenhauer D. R., Bellew T. M., Bork R. W., Srivastava P. K., Shinriki N., Lloyd R. S., Guengerich F. P. Characterization of cDNA, mRNA's, and proteins related to human liver microsomal cytochrome P450 (s)-mephenytoin 4′-hydroxylase. Biochemistry 1988; 27: 6929–6940
  • Gonzalez F. J. Human cytochromes P450: problems and prospects. Trends in Pharmacological Sciences 1992; 13: 346–352
  • Goldstein J. A., De Morais S. M. Biochemistry and molecular biology of the human CYP2C subfamily. Pharmacogenetics 1994; 6: 285–299
  • Graham F. L., van der Eb A. J. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 1973; 52: 456–467
  • Guengerich F. P. Characterization of human microsomal cytochrome P450 enzymes. Annual Review in Pharmacological Toxicology 1989a; 29: 241–264
  • Guengerich F. P. Polymorphism of cytochrome P-450 in humans. Trends in Pharmacological Sciences 1989b; 10: 107–109
  • Kiefer F., Wiebel F. J. V79 Chinese hamster cells express cytochrome P-450 activity after simultaneous exposure to polycyclic aromatic hydrocarbons and aminophylline. Toxicology Letters 1989; 48: 265–273
  • Knodell R. G., Hall S. D., Wilkinson G. R., Guengerich F. P. Hepatic metabolism of tolbutamide: characterization of the form of cytochrome-P450 involved in methyl hydroxylation and relationship to in vivo disposition. Journal of Pharmacological and Experimental Therapeutics 1987; 241: 1112–1119
  • Lehman T. D., Transon C., Bonnabry P., Dayer P. A major role for cytochrome P450TB (CYP2C subfamily) in the actions of non-steroidal antiinflammatory drugs. Drugs in Experimental Clinical Research 1993a; 19: 189–195
  • Leeman T., Transon C., Dayer P. Cytochrome P450TB (CYP2C): A major monooxygenase catalyzing diclofenac 4′-hydroxylation in human liver. Life Sciences 1993b; 52: 29–34
  • Miller A. D., Rosman G. J. Improved retroviral vectors for gene transfer and expression. Biotechniques 1989; 7: 980–990
  • Miners J. O., Smith K. J., Robson R. A., McManus M. E., Veronese M. E., Birkett D. J. Tolbutamide hydroxylation by human liver microsomes. Kinetic characterization and relationship to other cytochrome P-450 dependent xenobiotic oxidations. Biochemical Pharmacology 1988; 37: 1137–1144
  • Morel F., Beaune P. H., Ratanasavanh D., Flinois J. P., Yang C. S., Guengerich F. P., Guillouzo A. Expression of cytochrome P-450 enzymes in cultured human hepatocytes. European Journal of Biochemistry, 191: 437–444
  • Rettie A. E., Korzekwa K. R., Kunze K. L., Lawrence R. F., Eddy A. C., Aoyama T., Gelboin H. V., Gonzalez F. J., Trager W. F. Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions. Chemical Research in Toxicology 1992; 5: 54–59
  • Rodrigues A. D., Kukula M. J., Roberts E. M., Quellet D., Rodger T. R. [O-methyl 14C]naproxen O-demethylase activity in human liver microsomes. Evidence for the involvement of cytochrome P4501A2 and P4502C9/10. Drug Metabolism and Disposition 1996; 24: 126–136
  • Tracy T. S., Rosenbluth B. W., Wrighton S. A., Gonzalez F. J., Korzekwa K. R. Role of cytochrome P450 2C9 and an allelic variant in the 4′-hydroxylation of (R)- and (S)-flurbiprofen. Biochemical Pharmacology 1995; 49: 1269–1275
  • Wiebel F. J., Kiefer F., Cumpelik O. Expression of monomorphic and polymorphic acetyltransferase in V79 cells differing in sensitivity to 1,6-dinitropyrene (1,6-DNP). Proceedings of the American Association for Cancer Research, Baltimore, 1992, M. Michal. Waverley Press Inc., 154, 20–23 March 1992, San Diego, CA, vol. 33, Abstract no. 923
  • Zhao J., Leeman T., Dayer P. In vitro oxidation of oxicam NSAIDs by a human liver cytochrome P450. Life Sciences 1992; 51: 575–581

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.