Gender differences in ethanol oxidation and cytochrome P4502E1 content and functions in hepatic microsomes from alcohol-preferring and non-preferring rats

References

• Albano E., Tomasi A., Persson J. O., Terelius Y., Goria Gatti L., Ingelman-Sundberg M., Dianzani M. U. Cytochrome P450 2E1 mediated free radical activation of aliphatic alcohols. Biochemical Pharmacology 1991; 41: 1895–1903
   PubMed Web of Science ®Google Scholar
• Anders M. W. Bioactivation mechanisms and hepatocellular damage. The Liver Biology and Pathobiology, I. M. Arias, W. B. Jakoby, H. Popper, D. Schachter, D. A. Schafritz. Raven, New York 1988; 389–400
   Google Scholar
• Azzalis L. A., Simon K. A., Giavarotti L., Junqueira V. B. C., Porta E. A. Absence of stimulation of hepatic microsomal ethanol oxidizing system (MEOS) by chronic ethanol feeding in rats. Biochemical Archives 1994; 10: 221–235
   Google Scholar
• Carlson G. P. Influence of ethanol on microsomal p-nitrophenol hydroxylation and ethoxy-resorufin deethylation in rat liver and lung. Journal of Toxicology and Environmental Health 1991; 32: 153–159
   PubMed Web of Science ®Google Scholar
• De Matteis F. Loss of liver cytochrome P-450 caused by chemicals. Heme and Hemoproteins, F. De Matteis, W. N. Aldridge. Springer, New York 1978; 95–128
   Google Scholar
• Ekstrom G., von Bahr C., Ingelman-Sundberg M. Human liver microsomal cytochrome P450-IIE1. Immunological evaluation of its contribution to microsomal ethanol oxidation, carbon tetrachloride reduction, NADPH oxidase activity. Biochemical Pharmacology 1989; 38: 689–693
   PubMed Web of Science ®Google Scholar
• Eriksson K. Genetic selection for voluntary alcohol consumption in the albino rat. Science 1968; 159: 739–741
   PubMedGoogle Scholar
• Eriksson C. J. Ethanol and acetaldehyde metabolism in rat strains genetically selected for their ethanol preference. Biochemical Pharmacology 1973; 22: 2283–2292
   PubMedGoogle Scholar
• Fadda F., Mosca E., Colombo G., Gessa G. L. Voluntary ethanol consumption increases dopamine metabolism in the rat brain. Biomedical and Social Aspects of Alcohol and Alcoholism, K. Kuriyama, A. Takada, H. Ishii. Elsevier, New York 1988; 211–216
   Google Scholar
• French T. A., Atkinson N., Petersen D. R., Chung L. W. K. Differential induction of hepatic microsomal ethanol and drug metabolism by 3-methylcholanthrene in ‘LS’ and ‘SS’ mice. Journal of Pharmacology and Experimental Therapeutics 1979; 209: 404–410
   PubMedGoogle Scholar
• Gonzalez F. The molecular biology of cytochrome P450s. Pharmacological Reviews 1989; 40: 243–288
   Web of Science ®Google Scholar
• Koivula T., Koivusalo M., Lindros K. O. Liver aldehyde and alcohol dehydrogenase activities in rat strains selected for their ethanol preference. Biochemical Pharmacology 1975; 24: 1807–1811
   PubMed Web of Science ®Google Scholar
• Koop D. R., Laethem C. L., Schnier G. G. Identification of ethanol-inducible P-450 3a(P450IIE1) as a benzene and phenol hydroxylase. Toxicology and Applied Pharmacology 1989; 98: 278–288
   PubMed Web of Science ®Google Scholar
• Koop D. R., Nordblom G. D., Coon M. J. Immunochemical evidence for a role of cytochrome P450 in liver microsomal ethanol oxidation. Archives of Biochemistry and Biophysics 1984; 235: 228–238
   PubMed Web of Science ®Google Scholar
• Kunitoh S., Tanaka T., Imaoka S., Funae Y., Monna Y. M. Contribution of cytochrome P450s to MEOS (microsomal ethanol-oxidizing system): a specific and sensitive assay of MEOS activity by HPLC with fluorescence labeling. Alcohol & Alcoholism 1993; 28: 63–68
   Web of Science ®Google Scholar
• Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680–685
   PubMed Web of Science ®Google Scholar
• Levin W. T., Thomas P. E., Oldfield N., Ryan D. E. N-demethylation of N-nitrosodimethylamine catalyzed by purified rat hepatic and microsomal cytochrome P-450: isozyme specificity and role of cytochrome b5. Archives of Biochemistry and Biophysics 1986; 248: 158–165
   PubMed Web of Science ®Google Scholar
• Lieber C. S. The microsomal ethanol oxidizing system: its role in ethanol and xenobiotic metabolism. Biochemical Society Transactions 1988; 16: 232–239
   PubMed Web of Science ®Google Scholar
• Libber C. S. Interactions of ethanol with drugs, hepatotoxic agents, carcinogens and vitamins. Alcohol & Alcoholism 1990; 25: 157–176
   PubMedGoogle Scholar
• Lindros K. O., Cai Y., Penttila K. E. Role of ethanol-inducible cytochrome P-450 IIE1 in carbon tetrachforide-induced damage to centrilobular hepatocytes from ethanol-treated rats. Hepatology 1990; 12: 1092–1097
   PubMed Web of Science ®Google Scholar
• Liu S. J., Ramsey R. K., Fallon H. J. Effects of ethanol on hepatic microsomal drug-merabolizing enzymes in the rat. Biochemical Pharmacology 1975; 24: 369–378
   PubMedGoogle Scholar
• Lir Z., Franklin M. R. Cytochrome P-450 ligands: metyrapone revisited. Archives of Biochemistry and Biophysics 1985; 241: 397–402
   PubMedGoogle Scholar
• Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 1951; 193: 265–275
   PubMed Web of Science ®Google Scholar
• Luu-The V., Cumps J., Dumont P. Metyrapone-reduced cytochrome P-450 complex: a specific method for the determination of the phenobarbital-inducible form of rat hepatic microsomal cytochrome P-450. Biochemical and Biophysical Research Communications 1980; 93: 776–781
   PubMed Web of Science ®Google Scholar
• Mezey E., Potter J. J., Reed W. D. Ethanol oxidation by a component of liver microsomes rich in cytochrome P-450. Journal of Biological Chemistry 1973; 248: 1183–1187
   PubMed Web of Science ®Google Scholar
• Mitchell J. R., Jollows D. J. Metabolic activation of drugs to toxic substances. Gastroenterology 1975; 68: 392–410
   PubMed Web of Science ®Google Scholar
• Monostory K., Vereckzey L. The effect of phenobarbital and dexamethasone co-administration on the activity of rat liver P450 system. Biochemical and Biophysical Research Communications 1994; 203: 351–358
   PubMedGoogle Scholar
• Nebbia C., Dacasto M., Gennaro Soffietti M., Rasero R., Principato G. B., di Simplicio P. Inhibition of hepatic xenobiotic metabolism and of glutathione-dependent enzyme activities by zinc ethylene-bis-dithiocarbamate in the rabbit. Pharmacology & Toxicology 1993; 73: 233–239
   PubMedGoogle Scholar
• Omura T., Sato R. The carbon monoxide binding pigment of liver microsomes. Journal of Biological Chemistry 1964; 239: 2370–2385
   PubMed Web of Science ®Google Scholar
• Ohnishi K., Lieber C. S. Reconstitution of the microsomal ethanol oxidizing system (MEOS). Journal of Biological Chemistry 1977; 252: 7124–7131
   PubMed Web of Science ®Google Scholar
• Puapairoj L. C., Cui L., Ogawa K., Akagi K., Hasegawa R., Ito N. Effect of ethanol on paraquat toxicity in F-344 rats. Food and Chemical Toxicology 1994; 32: 379–386
   PubMed Web of Science ®Google Scholar
• Randoin L., Causeret Y. Constitution d'un regime alimentaire équilibré pour les jeunes rats blancs destinés au dosage des vitamines par le methodes biologiques. Bulletin de la Societé des Sciences Alimentaires 1947; 35: 14–21
   Google Scholar
• Raucy J. L., Kraner J. C., Lasker J. M. Bioactivation of halogenated hydrocarbons by cytochrome P4502E1. Critical Reviews in Toxicology 1993; 23: 1–20
   PubMed Web of Science ®Google Scholar
• Reinke L. A., Moyer M. J. p-Nitrophenol hydroxylation. A microsomal oxidation which is highly inducible by ethanol. Drug Metabolism and Disposition 1985; 13: 548–552
   PubMed Web of Science ®Google Scholar
• Rikans L. E., Snowden C. D., Moore D. R. Influence of aging on ethanol and acetaldehyde oxidation in female rat liver. Gerontology 1990; 36: 185–192
   PubMedGoogle Scholar
• Sato C., Nakano M., Lieber C. S. Increased hepatotoxicity of acetaminophen after chronic ethanol consumption in the rat. Gastroenterology 1981; 80: 140–148
   PubMed Web of Science ®Google Scholar
• Shibayama Y. Hepatotoxicity of carbon tetrachloride after chronic ethanol consumption. Experimental and Molecular Pathology 1988; 49: 234–242
   PubMed Web of Science ®Google Scholar
• Teschke R., Gellert J. Hepatic microsomal ethanol-oxidizing system (MEOS): metabolic aspects and clinical implication. Alcoholism: Clinical and Experimental Research 1986; 10: 20–32
   PubMed Web of Science ®Google Scholar
• Towbin H., Staehelin T., Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Proceedings of the National Academy of Sciences, USA 1979; 76: 4350–4354
   PubMed Web of Science ®Google Scholar
• Ueng T. H., Ueng Y. F., Tsai J. N., Chao I. C., Chen T. L., Park S. S., Iwasaki M., Guengerich F. P. Induction and inhibition of cytochrome P-450-dependent monooxygenases in hamster tissues by ethanol. Toxicology 1993; 81: 145–154
   PubMed Web of Science ®Google Scholar
• Van De Wiel J. A. G., Fijneman P. H. S., Teeuw K. B., van Omnen B., Noordhoek J., Bos R. P. Influence of long-term ethanol treatment on rat liver biotransformations enzymes. Alcohol 1993; 10: 397–402
   PubMedGoogle Scholar
• Van de Wiel J. A. G., Meuwissen M., Kooy H., Fijneman P. H. S., Noordhoek J., Bos R. P. The influence of long term ethanol treatment on in vitro biotransformation of benzo-(a)pyrene in microsomes of liver, lung, small intestine from male and female rats. Biochemical Pharmacology 1992; 44: 1977–1984
   PubMedGoogle Scholar
• Winters D. K., Cederbaum A. I. The content and activity of cytochrome P-450 2E1 in liver microsomes from alcohol-preferring and non-preferring rats. Alcohol & Alcoholism 1992; 27: 63–70
   PubMedGoogle Scholar
• Wortelboer H. M., de Kruif C. A., van Iersel A. A. I., Falke H. E., Noordhoek J., Blaauboer B. Comparison of cytochrome P-450 isoenzyme profile in rat liver and hepatocyte cultures. The effects of model inducers on apoproteins and biotransformation activities. Biochemical Pharmacology 1991; 42: 381–390
   PubMed Web of Science ®Google Scholar