Dimethyl acetals, an indirect marker of the endogenous antioxidant plasmalogen level, are reduced in blood lipids of Sudanese pre-eclamptic subjects whose background diet is high in carbohydrate

References

• Baker AM, Klein RL, Moss KL, Haeri S, Boggess K. 2009. Maternal serum dyslipidemia occurs early in pregnancy in women with mild but not severe preeclampsia. American Journal of Obstetrics and Gynecology 201:293.e1–e4.
   Web of Science ®Google Scholar
• Bellamy L, Casas JP, Hingorani AD, Williams DJ. 2007. Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. British Medical Journal 335:974.
   PubMed Web of Science ®Google Scholar
• Bodnar LM, Catov JM, Klebanoff MA, Ness RB, Roberts JM. 2007. Prepregnancy body mass index and the occurrence of severe hypertensive disorders of pregnancy. Epidemiology 18:234–239.
   PubMed Web of Science ®Google Scholar
• Bodnar LM, Ness RB, Markovic N, Roberts JM. 2005. The risk of preeclampsia rises with increasing prepregnancy body mass index. Annals of Epidemiology 15:475–482.
   PubMed Web of Science ®Google Scholar
• Brites P, Waterham HR, Wanders RJ. 2004. Functions and biosynthesis of plasmalogens in health and disease. Biochimica et Biophysica Acta 1636:219–231.
   PubMed Web of Science ®Google Scholar
• Brown MA, Lindheimer MD, de Swiet M, Van Assche A, Moutquin JM. 2001. The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertension in Pregnancy 20: IX–XIV.
   PubMed Web of Science ®Google Scholar
• Chalas J, Audibert F, Francoual J, Le Bihan B, Frydman R, Lindenbaum A. 2002. Concentrations of apolipoproteins E, C2, and C3 and lipid profile in preeclampsia. Hypertension in Pregnancy 21:199–204.
   PubMed Web of Science ®Google Scholar
• Clausen T, Slott M, Solvoll K, Drevon CA, Vollset SE, Henriksen T. 2001. High intake of energy, sucrose, and polyunsaturated fatty acids is associated with increased risk of preeclampsia. American Journal of Obstetrics and Gynecology 185:451–458.
   PubMed Web of Science ®Google Scholar
• Dekker GA, Sibai BM. 1998. Etiology and pathogenesis of preeclampsia: current concepts. American Journal of Obstetrics and Gynecology 179: 1359–1375.
   PubMed Web of Science ®Google Scholar
• Duley L. 2003. Pre-eclampsia and the hypertensive disorders of pregnancy. British Medical Bulletin 67:161–176.
   PubMed Web of Science ®Google Scholar
• Engelmann B, Bräutigam C, Thiery J. 1994. Plasmalogen phospholipids as potential protectors against lipid peroxidation of low density lipoproteins. Biochemical and Biophysical Research Communications 204:1235–1242.
   PubMedGoogle Scholar
• Enquobahrie DA, Williams MA, Butler CL, Frederick IO, Miller RS, Luthy DA. 2004. Maternal plasma lipid concentrations in early pregnancy and risk of preeclampsia. American Journal of Hypertension 17:574–581.
   PubMed Web of Science ®Google Scholar
• Farooqui AA, Rapoport SI, Horrocks LA. 1997. Membrane phospholipid alterations in Alzheimer's disease: deficiency of ethanolamine plasmalogens. Neurochemical Research 22:523–527.
   PubMed Web of Science ®Google Scholar
• Gorgas K, Teigler A, Komljenovic D, Just WW. 2006. The ether lipid-deficient mouse: tracking down plasmalogen functions. Biochimica et Biophysica Acta 1763:1511–1526.
   PubMed Web of Science ®Google Scholar
• Gratacós E, Casals E, Deulofeu R, Cararach V, Alonso PL, Fortuny A. 1998. Lipid peroxide and vitamin E patterns in pregnant women with different types of hypertension in pregnancy. American Journal of Obstetrics and Gynecology 178:1072–1076.
   PubMed Web of Science ®Google Scholar
• Gupta S, Aziz N, Sekhon L, Agarwal R, Mansour G, Li J . 2009. Lipid peroxidation and antioxidant status in preeclampsia: a systematic review. Obstetrical and Gynecological Survey 64:750–759.
   PubMed Web of Science ®Google Scholar
• Hannaford P, Ferry S, Hirsch S. 1997. Cardiovascular sequelae of toxaemia of pregnancy. Heart 77:154–158.
   PubMed Web of Science ®Google Scholar
• Heilmann L, Siekmann U, Schmid-Schönbein H, Ludwig H. 1981. Hemoconcentration and pre-eclampsia. Archives of Gynecology 231: 7–21.
   PubMedGoogle Scholar
• Hubel CA, McLaughlin MK, Evans RW, Hauth BA, Sims CJ, Roberts JM. 1996. Fasting serum triglycerides, free fatty acids, and malondialdehyde are increased in preeclampsia, are positively correlated, and decrease within 48 h post partum. American Journal of Obstetrics and Gynecology 174:975–982.
   PubMed Web of Science ®Google Scholar
• Huiskes VJ, Kuipers RS, Velzing-Aarts FV, Dijck-Brouwer DA, van der Meulen J, Muskiet FA. 2009. Higher de novo synthesized fatty acids and lower omega3- and omega6-long-chain polyunsaturated fatty acids in umbilical vessels of women with preeclampsia and high fish intakes. Prostaglandins Leukotrienes and Essential Fatty Acids 80:101–106.
   PubMedGoogle Scholar
• Folch J, Lees M, Sloane Stanley GH. 1957. A simple method for the isolation and purification of total lipides from animal tissues. Journal of Biological Chemistry 226:497–509.
   PubMed Web of Science ®Google Scholar
• Kaaja R. 1998. Insulin resistance syndrome in preeclampsia. Seminars in Reproductive Endocrinology 16:41–46.
   PubMedGoogle Scholar
• Khan KS, Wojdyla D, Say L, Gülmezoglu AM, Van Look PF. 2006. WHO analysis of causes of maternal death: a systematic review. Lancet 367:1066–1074.
   PubMed Web of Science ®Google Scholar
• Kulkarni AV, Mehendale SS, Yadav HR, Joshi SR. 2011. Reduced placental docosahexaenoic acid levels associated with increased levels of sFlt-1 in preeclampsia. Prostaglandins Leukotrienes and Essential Fatty Acids 84:51–55.
   PubMed Web of Science ®Google Scholar
• LaMarca BD, Ryan MJ, Gilbert JS. 2007. Murphy SR, Granger JP. Inflammatory cytokines in the pathophysiology of hypertension during preeclampsia. Current Hypertension Reports 9:480–485.
   PubMed Web of Science ®Google Scholar
• Lorentzen B, Henriksen T. 1998. Plasma lipids and vascular dysfunction in preeclampsia. Current Hypertension Reports 16:33–39.
   Google Scholar
• Lorentzen B, Drevon CA, Endresen MJ, Henriksen T. 1995. Fatty acid pattern of esterified and free fatty acids in sera of women with normal and pre-eclamptic pregnancy. Current Hypertension Reports 102:530–537.
   Google Scholar
• Lorentzen B, Endersen MJ, Clausen T, Henriksen T. 1994. Fasting serum free fatty acids and triglycerides are increased before 20 weeks of gestation in women who later develop preeclampsia. Current Hypertension Reports 13:103–109.
   Google Scholar
• Mahomed K, Williams MA, Woelk GB, Jenkins-Woelk L, Mudzamiri S, Longstaff L . 1998. Risk factors for pre-eclampsia among Zimbabwean women: maternal arm circumference and other anthropometric measures of obesity. Paediatric and Perinatal Epidemiology 12:253–262.
   PubMed Web of Science ®Google Scholar
• Mehendale S, Kilari A, Dangat K, Taralekar V, Mahadik S, Joshi S. 2008. Fatty acids, antioxidants, and oxidative stress in pre-eclampsia. International Journal of Gynaecology and Obstetrics 100:234–238.
   PubMed Web of Science ®Google Scholar
• Murphy EJ, Schapiro MB, Rapoport SI, Shetty HU. 2000. Phospholipid composition and levels are altered in Down syndrome brain. Brain Research 867:9–18.
   PubMed Web of Science ®Google Scholar
• Onrust S, Santema JG, Aarnoudse JG. 1999. Pre-eclampsia and the HELLP syndrome still cause maternal mortality in The Netherlands and other developed countries; can we reduce it? European Journal of Obstetrics, Gynecology, and Reproductive Biology 82:41–46.
   PubMedGoogle Scholar
• Pritchard JA. 1965. Changes in the blood volume during pregnancy and delivery. Anesthesiology 26:393–399.
   PubMed Web of Science ®Google Scholar
• Punthumapol C, Kittichotpanich B. 2008. Comparative study of serum lipid concentrations in preeclampsia and normal pregnancy. Journal of the Medical Association of Thailand 91:957–961.
   PubMedGoogle Scholar
• Qiu C, Sanchez SE, Larrabure G, David R, Bralley JA, Williams MA. 2006. Erythrocyte omega-3 and omega-6 polyunsaturated fatty acids and preeclampsia risk in Peruvian women. Archives of Gynecology and Obstetrics 274:97–103.
   PubMedGoogle Scholar
• Ray JG, Diamond P, Singh G, Bell CM. 2006. Brief overview of maternal triglycerides as a risk factor for pre-eclampsia. British Journal of Obstetrics and Gynaecology 113:379–386.
   Google Scholar
• Redman CW, Sargent IL. 2003. Pre-eclampsia, the placenta and the maternal systemic inflammatory response: a review. Placenta 24 (Suppl A): S21–S27.
   Google Scholar
• Roberts JM, Taylor RN, Goldfien A. 1991. Clinical and biochemical evidence of endothelial cell dysfunction in the pregnancy syndrome preeclampsia. American Journal of Hypertension 4:700–708.
   PubMed Web of Science ®Google Scholar
• Roberts JM, Taylor RN, Musci TJ, Rodgers GM, Hubel CA, McLaughlin MK. 1989. Preeclampsia: an endothelial cell disorder. American Journal of Obstetrics and Gynecology 161:1200–1204.
   PubMed Web of Science ®Google Scholar
• Robinson NJ, Minchell LJ, Myers JE, Hubel CA, Crocker IP. 2009. A potential role for free fatty acids in the pathogenesis of preeclampsia. Journal of Hypertension 27:1293–1302.
   PubMed Web of Science ®Google Scholar
• Romanowicz L, Bańkowski E. 2009. Lipid compounds of the umbilical cord vein and their alterations in preeclampsia. Biochimie 91:288–294.
   PubMedGoogle Scholar
• Rosenberg TJ, Garbers S, Chavkin W, Chiasson MA. 2003. Prepregnancy weight and adverse perinatal outcomes in an ethnically diverse population. Obstetrics and Gynecology 102(5 Pt 1):1022–1027.
   PubMedGoogle Scholar
• Sagen N, Koller O, Haram K. 1982. Haemoconcentration in severe pre-eclampsia. British Journal of Obstetrics and Gynaecology 89:802–805.
   PubMedGoogle Scholar
• Sibai B, Dekker G, Kupferminc M. 2005. Pre-eclampsia. Lancet 365:785–799.
   PubMed Web of Science ®Google Scholar
• Stenvinkel P, Diczfalusy U, Lindholm B, Heimbürger O. 2004. Phospholipid plasmalogen, a surrogate marker of oxidative stress, is associated with increased cardiovascular mortality in patients on renal replacement therapy. Nephrology, Dialysis, Transplantation 19:972–976.
   PubMed Web of Science ®Google Scholar
• Tham Kah Meng (2010) A study of coagulation potential in preeclampsia. MSc Thesis, Glasgow University.
   Google Scholar
• Vanderjagt DJ, Patel RJ, El-Nafaty AU, Melah GS, Crossey MJ, Glew RH. 2004. High-density lipoprotein and homocysteine levels correlate inversely in preeclamptic women in northern Nigeria. Acta Obstetricia et Gynecologica Scandinavica 83:536–542.
   PubMedGoogle Scholar
• Vanderlelie J, Venardos K, Clifton VL, Gude NM, Clarke FM, Perkins AV. 2005. Increased biological oxidation and reduced anti-oxidant enzyme activity in pre-eclamptic placentae. Placenta 26:53–58.
   PubMed Web of Science ®Google Scholar
• Velzing-Aarts FV, van der Klis FR, van der Dijs FP, Muskiet FA. 1999. Umbilical vessels of preeclamptic women have low contents of both n-3 and n-6 long-chain polyunsaturated fatty acids. American Journal of Clinical Nutrition 69:293–298.
   PubMedGoogle Scholar
• Villa PM, Laivuori H, Kajantie E, Kaaja R. 2009. Free fatty acid profiles in preeclampsia. Prostaglandins Leukotrienes and Essential Fatty Acids 81:17–21.
   PubMed Web of Science ®Google Scholar
• Villar J, Say L, Shennan A, Lindheimer M, Duley L, Conde-Agudelo A . 2004. Methodological and technical issues related to the diagnosis, screening, prevention, and treatment of pre-eclampsia and eclampsia. International Journal of Gynaecology and Obstetrics 85 (Suppl 1):S28–S41.
   Google Scholar
• von Tempelhoff GF, Heilmann L, Rudig L, Pollow K, Hommel G, Koscielny J. 2008. Mean maternal second-trimester hemoglobin concentration and outcome of pregnancy: a population-based study. Clinical and Applied Thrombosis/Hemostasis 14:19–28.
   PubMed Web of Science ®Google Scholar
• von Versen-Hoeynck FM, Powers RW. 2007. Maternal-fetal metabolism in normal pregnancy and preeclampsia. Frontiers in Bioscience 12:2457–2470.
   PubMed Web of Science ®Google Scholar
• Walsh SW. 1998. Maternal-placental interactions of oxidative stress and antioxidants in preeclampsia. Seminars in Reproductive Endocrinology 16:93–104.
   PubMedGoogle Scholar
• Walsh SW. 2007. Obesity: a risk factor for preeclampsia. Trends in Endocrinology and Metabolism 18:365–370.
   PubMed Web of Science ®Google Scholar
• Wang Y, Walsh SW, Kay HH. 2005. Placental tissue levels of nonesterified polyunsaturated fatty acids in normal and preeclamptic pregnancies. Hypertension in Pregnancy 24:235–245.
   PubMed Web of Science ®Google Scholar
• Wang Y, Walsh SW. 1996. Antioxidant activities and mRNA expression of superoxide dismutase, catalase, and glutathione peroxidase in normal and preeclamptic placentas. Journal of the Society for Gynecologic Investigation 3:179–184.
   PubMedGoogle Scholar
• Williams MA, Zingheim RW, King IB, Zebelman AM. 1995. Omega-3 fatty acids in maternal erythrocytes and risk of preeclampsia. Epidemiology 6:232–237.
   PubMed Web of Science ®Google Scholar
• Wiznitzer A, Mayer A, Novack V, Sheiner E, Gilutz H, Malhotra A . 2009. Association of lipid levels during gestation with preeclampsia and gestational diabetes mellitus: a population-based study. American Journal of Obstetrics and Gynecology 201:482.e1–e8.
   PubMed Web of Science ®Google Scholar
• Xu H, Shatenstein B, Luo ZC, Wei S, Fraser W. 2009. Role of nutrition in the risk of preeclampsia. Nutrition Reviews 67:639–657.
   PubMed Web of Science ®Google Scholar
• Yavin E, Gatt S. 1972. Oxygen-dependent cleavage of the vinyl-ether linkage of plasmalogens. 1. Cleavage by rat-brain supernatant. European Journal of Biochemistry 25:431–436.
   PubMedGoogle Scholar
• Zoeller RA, Lake AC, Nagan N, Gaposchkin DP, Legner MA, Lieberthal W. 1999. Plasmalogens as endogenous antioxidants: somatic cell mutants reveal the importance of the vinyl ether. Biochemical Journal 338 (Pt 3):769–776.
   PubMedGoogle Scholar