Homocysteine, folate and pregnancy outcomes

References

• Andersson A, Hultberg B, Brattstrom L, Isaksson A. 1992. Decreased serum homocysteine in pregnancy. European Journal of Clinical Chemistry and Clinical Biochemistry 30:377–379.
   PubMedGoogle Scholar
• Bonnette RE, Caudill MA, Boddie AM, Hutson AD, Kauwell GP, Bailey LB. 1998. Plasma homocyst(e)ine concentrations in pregnant and nonpregnant women with controlled folate intake. Obstetrics and Gynecology 92:167–170.
   PubMed Web of Science ®Google Scholar
• Bukowski R, Malone FD, Porter FT, Nyberg DA, Comstock CH, Hankins GD . 2009. Preconceptional folate supplementation and the risk of spontaneous preterm birth: a cohort study. PLoS Medicine 6:e1000061.
   PubMed Web of Science ®Google Scholar
• Burke G, Robinson K, Refsum H, Stuart B, Drumm J, Graham I. 1992. Intrauterine growth retardation, perinatal death, and maternal homocysteine levels. New England Journal of Medicine 326:69–70.
   PubMed Web of Science ®Google Scholar
• Celik H, Ayar A, Tug N. 2003. Hyperhomocysteinemia may be a resistance factor in tocolytic treatment with beta mimetics. Medical Hypotheses 61:580–582.
   PubMed Web of Science ®Google Scholar
• Charles DH, Ness AR, Campbell D, Smith GD, Whitley E, Hall MH. 2005. Folic acid supplements in pregnancy and birth outcome: re-analysis of a large randomised controlled trial and update of Cochrane review. Paediatric and Perinatal Epidemiology 19:112–124.
   PubMed Web of Science ®Google Scholar
• Christian P, Jiang T, Khatry SK, Leclerq SC, Shrestha SR, West KP, JR. 2006. Antenatal supplementation with micronutrients and biochemical indicators of status and subclinical infection in rural Nepal. American Journal of Clinical Nutrition 83:788–794.
   PubMed Web of Science ®Google Scholar
• Clarke R, Woodhouse P, Ulvik A, Frost C, Sherliker P, Refsum H . 1998. Variability and determinants of total homocysteine concentrations in plasma in an elderly population. Clinical Chemistry 44:102–107.
   PubMed Web of Science ®Google Scholar
• Czeizel AE, Dudas I. 1992. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. New England Journal of Medicine 327:1832–1835.
   PubMed Web of Science ®Google Scholar
• Czeizel AE, Puhó EH, Langmar Z, Ács N, Bánhidy F. 2010. Possible association of folic acid supplementation during pregnancy with reduction of preterm birth: a population-based study. European Journal of Obstetrics, Gynecology, and Reproductive Biology 148:135–140.
   PubMed Web of Science ®Google Scholar
• Dekker GA, De Vries JI, Doelitzsch PM, Huijgens PC, Von Blomberg BM, Jakobs C . 1995. Underlying disorders associated with severe early-onset preeclampsia. American Journal of Obstetrics and Gynecology 173:1042–1048.
   PubMed Web of Science ®Google Scholar
• De Weerd S, Steegers-Theunissen RP, De Boo TM, Thomas CM, Steegers EA. 2003. Maternal periconceptional biochemical and hematological parameters, vitamin profiles and pregnancy outcome. European Journal of Clinical Nutrition 57:1128–1134.
   PubMed Web of Science ®Google Scholar
• Goddijn-Wessel TA, Wouters MG, Van de Molen EF, Spuijbroek MD, Steegers-Theunissen RP, Blom HJ . 1996. Hyperhomocysteinemia: a risk factor for placental abruption or infarction. European Journal of Obstetrics, Gynecology, and Reproductive Biology 66:23–29.
   PubMed Web of Science ®Google Scholar
• Hibbard BM. 1964. The role of folic acid in pregnancy; with particular reference to anaemia, abruption and abortion. Journal of Obstetrics and Gynaecology of the British Commonwealth 71:529–542.
   PubMedGoogle Scholar
• Hibbard ED, Smithells RW. 1965. Folic acid metabolism and human embryopathy. Lancet 285:1254.
   Google Scholar
• Hong SC, Ha EH, Han JY, Park H, Ha M, Kim Y . 2011. The relationship between folic acid supplementation and serum folate level in early pregnancy and pregnancy outcomes: MOCEH (Mothers’ and Children's Environmental Health) study. Journal of Population Therapeutics and Clinical Pharmacology 18:e344.
   Google Scholar
• Jongbloet PH, Verbeek AL, Den Heijer M, Roeleveld N. 2008. Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms resulting in suboptimal oocyte maturation: a discussion of folate status, neural tube defects, schizophrenia, and vasculopathy. Journal of Experimental and Clinical Assisted Reproduction 5:5.
   PubMedGoogle Scholar
• Miller JW, Nadeau MR, Smith D, Selhub J. 1994. Vitamin B-6 deficiency vs folate deficiency: comparison of responses to methionine loading in rats. American Journal of Clinical Nutrition 59:1033–1039.
   PubMed Web of Science ®Google Scholar
• Mills JL, McPartlin JM, Kirke PN, Lee YJ, Conley MR, Weir DG . 1995. Homocysteine metabolism in pregnancies complicated by neural-tube defects. Lancet 345:149–151.
   PubMed Web of Science ®Google Scholar
• Molloy AM, Daly S, Mills JL, Kirke PN, Whitehead AS, Ramsbottom D . 1997. Thermolabile variant of 5,10-methylenetetrahydrofolate reductase associated with low red-cell folates: implications for folate intake recommendations. Lancet 349:1591–1593.
   PubMed Web of Science ®Google Scholar
• Moore CV, Bierbaum OS, Welch AD, Wright LD. 1945. The activity of synthetic Lactobacillus casei factor (‘folic acid’) as an anti-pernicious anemia substance. I. Observations on four patients: two with Addisonian pernicious anemia, one with non-tropical sprue and one with pernicious anemia of pregnancy. Journal of Laboratory and Clinical Medicine 30:1056–1069.
   PubMed Web of Science ®Google Scholar
• MRC Vitamin Study Research Group. 1991. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 338:131–137.
   PubMed Web of Science ®Google Scholar
• Nygard O, Refsum H, Ueland PM, Stensvold I, Nordrehaug JE, Kvale G . 1997. Coffee consumption and plasma total homocysteine: The Hordaland Homocysteine Study. American Journal of Clinical Nutrition 65:136–143.
   PubMed Web of Science ®Google Scholar
• Powers RW, Evans RW, Majors AK, Ojimba JI, Ness RB, Crombleholme WR . 1998. Plasma homocysteine concentration is increased in preeclampsia and is associated with evidence of endothelial activation. American Journal of Obstetrics and Gynecology 179:1605–1611.
   PubMed Web of Science ®Google Scholar
• Rajkovic A, Mahomed K, Malinow MR, Sorenson TK, Woelk GB, Williams MA. 1999. Plasma homocyst(e)ine concentrations in eclamptic and preeclamptic African women postpartum. Obstetrics and Gynecology 94:355–360.
   PubMed Web of Science ®Google Scholar
• Roberts JM, Taylor RN, Goldfien A. 1991. Clinical and biochemical evidence of endothelial cell dysfunction in the pregnancy syndrome preeclampsia. American Journal of Hypertension 4:700–708.
   PubMed Web of Science ®Google Scholar
• Scholl TO, Hediger ML, Schall JI, Khoo CS, Fischer RL. 1996. Dietary and serum folate: their influence on the outcome of pregnancy. American Journal of Clinical Nutrition 63:520–525.
   PubMed Web of Science ®Google Scholar
• Siega-Riz AM, Savitz DA, Zeisel SH, Thorp JM, Herring A. 2004. Second trimester folate status and preterm birth. American Journal of Obstetrics and Gynecology 191:1851–1857.
   PubMed Web of Science ®Google Scholar
• Steegers-Theunissen RP, Boers GH, Blom HJ, Trijbels FJ, Eskes TK. 1992. Hyperhomocysteinaemia and recurrent spontaneous abortion or abruptio placentae. Lancet 339:1122–1123.
   PubMed Web of Science ®Google Scholar
• Steegers-Theunissen RP, Boers GH, Trijbels FJ, Eskes TK. 1991. Neural-tube defects and derangement of homocysteine metabolism. New England Journal of Medicine 324:199–200.
   PubMed Web of Science ®Google Scholar
• Tamura T, Picciano MF. 2006. Folate and human reproduction. American Journal of Clinical Nutrition 83:993–1016.
   PubMed Web of Science ®Google Scholar
• Troen AM, Mitchell B, Sorensen B, Wener MH, Johnston A, Wood B . 2006. Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women. Journal of Nutrition 136:189–194.
   PubMed Web of Science ®Google Scholar
• Van der Molen EF, Verbruggen B, Novakova I, Eskes TK, Monnens LA, Blom HJ. 2000. Hyperhomocysteinemia and other thrombotic risk factors in women with placental vasculopathy. British Journal of Obstetrics and Gynaecology 107:785–791.
   Google Scholar
• Vollset SE, Refsum H, Irgens LM, Emblem BM, Tverdal A, Gjessing HK . 2000. Plasma total homocysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine Study. American Journal of Clinical Nutrition 71:962–968.
   PubMed Web of Science ®Google Scholar
• Walker MC, Smith GN, Perkins SL, Keely EJ, Garner PR. 1999. Changes in homocysteine levels during normal pregnancy. American Journal of Obstetrics and Gynecology 180:660–664.
   PubMed Web of Science ®Google Scholar
• Wouters MG, Boers GH, Blom HJ, Trijbels FJ, Thomas CM, Borm GF . 1993. Hyperhomocysteinemia: a risk factor in women with unexplained recurrent early pregnancy loss. Fertility and Sterility 60:820–825.
   PubMed Web of Science ®Google Scholar