References
- Liu, S. Y., Sylvester, D. M. (1994). Antiplatelet structure-activity relationship of tetramethylpyrazine. Life Sci 55:1317–1326.
- Cheng, X. R., Zhang, L., Hu, J. J., Sun, L., Du, G. H. (2007). Neuroprotective effects of tetramethylpyrazine on hydrogen peroxide–induced apoptosis in PC12 cells. Cell Biol Int 31:438–443.
- Liao, S. L., Kao, T. K., Chen, W. Y., Lin, Y. S., Chen, S. Y., Raung, S. L., et al. (2004). Tetramethylpyrazine reduces ischemic brain injury in rats. Neurosci Lett 372:40–45.
- Kao, T. K., Ou, Y. C., Kuo, J. S., Chen, W. Y., Liao, S. L., Wu, C. W., et al. (2006). Neuroprotection by tetramethylpyrazine against ischemic brain injury in rats. Neurochem Int 48:166–176.
- Liang, S. D., Gao, Y., Xu, C. S., Xu, B. H., Mu, S. N. (2004). Effect of tetramethylpyrazine on acute nociception mediated by signaling of P2X receptor activation in rat. Brain Res 995:247–252.
- Fu, Y. S., Lin, Y. Y., Chou, S. C., Tsai, T. H., Kao, L. S., Hsu, S. Y., et al. (2008). Tetramethylpyrazine inhibits activities of glioma cells and glutamate neuro-excitotoxicity: potential therapeutic application for treatment of gliomas. Neuro- Oncology 10:139–152. [Epub 2008 Feb 26].
- Juan, S. H., Chen, C. H., Hsu, Y. H., Hou, C. C., Chen, T. H., Lin, H., et al. (2007). Tetramethylpyrazine protects rat renal tubular cell apoptosis induced by gentamicin. Nephrol Dial Transpl 22:732–739.
- Liu, C. F., Lin, C. C., Ng, L. T., Lin, S. C. (2002). Hepatoprotective and therapeutic effects of tetramethylpyrazine on acute econazole-induced liver injury. Planta Med 68:510–514.
- Chang, F. C., Chen, K. J., Lin, J. G., Hong, C. Y., Huang, Y. T. (1998). Effects of tetramethylpyrazine on portal hypertensive rats. J Pharm Pharmacol 50:881–884.
- Chang, F. C., Huang, Y. T., Lin, H. C., Hong, C. Y., Lin, J. G., Chen, K. J. (1999). Beneficial effects of combined terlipressin and tetramethylpyrazine administration on portal hypertensive rats. Can J Physiol Pharmacol 77:618–624.
- Huang, Y. T, Chang, F. C., Chen, K. J., Hong, C. Y. (1999). Acute hemodynamic effects of tetramethylpyrazine and tetrandrine on cirrhotic rats. Planta Med 65:130–134.
- Leclercq, I. A., Farrell, G. C., Schriemer, R., Robertson, G. R. (2002). Leptin is essential for the hepatic fibrogenic response to chronic liver injury. J Hepatol 37:206–213.
- Bethanis, S. K., Theocharis, S. E. (2006). Leptin in the field of hepatic fibrosis: a pivotal or an incidental player? Dig Dis Sci 51:1685–1696.
- Ikejima, K., Honda, H., Yoshikawa, M., Hirose, M., Kitamura, T., Takei, Y., et al. (2001). Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals. Hepatology 34:288–297.
- Saxena, N. K., Ikeda, K., Rockey, D. C., Friedman, S. L., Anania, F. A. (2002). Leptin in hepatic fibrosis: evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice. Hepatology 35:762–771.
- Honda, H., Ikejima, K., Hirose, M., Yoshikawa, M., Lang, T., Enomoto, N., et al. (2002). Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver. Hepatology 36:12–21.
- Tang, M., Potter, J. J., Mezey, E. (2002). Leptin enhances the effect of transforming growth factor beta in increasing type I collagen formation. Biochem Biophys Res Commun 297:906–911.
- Tang, M., Potter, J. J., Mezey, E. (2003). Activation of the human alpha1(I) collagen promoter by leptin is not mediated by transforming growth factor beta responsive elements. Biochem Biophys Res Commun 312:629–633.