References
- Agarwal, M. L, Agarwal, A., Taylor, W. R., Stark, G. R. (1995). p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts. Proc Natl Acad Sci USA 92:8493–8497.
- Alao, J. P. (2007). The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention. Mol Cancer 6:1–16.
- Angel, P., Karin, M. (1991). The role of Jun, Fos, and the AP- 1 complex in cell proliferation and transformation. Biochim Biophys Acta 1072:129–157.
- Brissette, W. H., Baker, D. A., Stam, E. J., Umland, J. P., Griffiths, R. J. (1995). GM-CSF rapidly primes mice for enhanced cytokine production in response to LPS and TNF. Cytokine 7:291–295.
- Chea, A., Hout, S., Long, C., Marcourt, L., Faure, R., Azas, N., et al. (2006). Antimalarial activity of sesquiterpene lactones from Vernonia cinerea. Chem Pharm Bull 54:1437–1439.
- Chen, X., Zhan, Z. J., Yue, J. M. (2006). Sesquiterpenoids from Vernonia cinerea. Nat Prod Res 20:125–129.
- Choi, J. H., Brummer, E., Kang, Y. J., Jones, P. P., Stevens, D. A. (2006). Inhibitor kappaB and nuclear factor kappaB in granulocyte-macrophage colony-stimulating factor antagonism of dexamethasone suppression of the macrophage response to Aspergillus fumigatus conidia. J Infect Dis 193:1023–1028.
- Chu, D., Qiu, J. X., Grafe, M., Fabian, R., Kent, T. A., Rassin, D., et al. (2002). Delayed cell death signaling in traumatized central nervous system: hypoxia. Neurochem Res 27:97–106.
- Cohen, G. M. (1997). Caspases: the executioners of apoptosis. Biochem J 326:1–16.
- Cox, G., Gauldie, J., Jordana, M. (1992). Bronchial epithelial cell-derived cytokines (G-CSF and GM-CSF) promote the survival of peripheral blood neutrophils in vitro. Am J Respir Cell Mol Biol 7:507–513.
- Dignam, J. D., Lebovitz, R. M., Roeder, R. G. (1983). Accurate transcription initiation by RA polymerase II in a soluble extract from isolated mammalian tissue. Nucleic Acids Res 11:1475–1489.
- Dinarello, C. A. (1996). Biological basis for interleukin-1 in disease. Blood 87:2095–2147.
- Farrow, S. N., Brown, R. (1996). New members of the Bcl-2 family and their protein partners. Curr Opin Genet Dev 6:45–49.
- Gallo, O., Bianchi, S., Porfirio, B. (1995). Bcl-2 overexpression and smoking history in head and neck cancer. J Natl Cancer Inst 87:1024–1025.
- Hehner, S. P., Heinrich, M., Bork, P. M., Vogt, M., Ratter, F., Lehmann, V., et al. (1998). Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta. J Biol Chem 273:1288–1297.
- Hengartner, M. O. (2000). The biochemistry of apoptosis. Nature 407:770–777.
- Huang, C., Chen, N., Ma, W. Y., Dong, Z. (1998). Vanadium induce AP-1- and NF-κB-dependent transcription activity. Int J Oncol 13:711–715.
- Il’yasova, D., Colbert, L. H, Harris, T. B., Newman, A. B., Bauer, D. C., Satterfield, S., et al. (2005). Circulating levels of inflammatory markers and cancer risk in the health aging and body composition cohort. Cancer Epidemiol Biomarkers Prev 14:2413–2418.
- Jeffers, J. R., Parganas, E., Lee, Y., Yang, C., Wang, J., Brennan, J., et al. (2003). PUMA is an essential mediator of p53-dependent and -independent apoptotic pathways. Cancer Cell 4:321–328.
- Knudsen, K. E., Diehl, J. A., Haiman, C. A., Knudsen, E. S. (2006). Cyclin D1: polymorphism, aberrant splicing, and cancer risk. Oncogene 25:1620–1628.
- Kohler, C., Orrenius, S., Zhivotovsky, B. (2002). Evaluation of caspase activity in apoptotic cells. J Immunol Methods 265:97–110.
- Komarova, E. A., Gudkov, A. V. (2001). Chemoprotection from p53-dependent apoptosis: potential clinical applications of the p53 inhibitors. Biochem Pharmacol 62:657–667.
- Kumar, P. P., Kuttan, G. (2009). Vernonia cinerea L. scavenges free radicals and regulates nitric oxide and proinflammatory cytokines profile in carrageenan induced paw edema model. Immunopharm Immunotoxicol 31:94–102
- Kuo, Y. H., Kuo, Y. J., Yu, A. S., Wu, M. D, Ong, C. W., Kuo, L. M. Y., et al. (2003). Two novel sesquiterpene lactones, cytotoxic vernolide-A and -B, from Vernonia cinerea. Chem Pharm Bull 51:425–426.
- Lane, D. P., Lain, S. (2002). Therapeutic exploitation of the p53 pathway. Trends Mol Med 8:S38–S42.
- Lee, C. C. R., Fukushima, S. (1998). Alterations in cyclin D1, p53, and the cell cycle related elements: implications for distinct genetic pathways of urinary bladder carcinogenesis. Urol Oncol 4:58–72.
- Lin, W. W., Karin, M. A. (2007). Cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 117:1175–1183.
- Lorenzo, H. K., Susin, S. A. (2004). Mitochondrial e!ectors in caspase-independent cell death. FEBS Lett 557:14–20
- Macarthur, M., Hold, G. L., El-Omar, E. M. (2004). Inflammation and cancer II. Role of chronic inflammation and cytokine gene polymorphisms in the pathogenesis of gastrointestinal malignancy. Am J Physiol Gastrointest Liver Physiol 286:G515–G520.
- Mori, N., Fujii, M., Ikeda, S., Yamada, Y., Tomonaga, M., Ballard, W., et al. (1999). Constitutive activation of NF-κB in primary adult T-cell leukemia cells. Blood 93:2360–2368.
- Park, B. K., Zhang, H., Zeng, Q., Dai, J., Keller, E. T., Giordano, T., et al. (2007). NF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF. Nat Med 13:62–69.
- Perkins, N. D. (1997). Achieving transcriptional specificity with NF-κB. Int J Biochmz Cell Biol 29:1433–1448.
- Pikarsky, E., Ben-Neriah, Y. (2006). NF-κB inhibition: a double-edged sword in cancer?. Eur J Cancer 42:779–784
- Ridker, P. M., Hennekens, C. H., Buring, J. E., Rifai, N. (2000). C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. NEJM 342:836–843.
- Schwartsmann, G., Ratain, M. J., Cragg, G. M., Wong, J. E., Saijo, N., Parkinson, D. R., et al. (2002). Anticancer drug discovery and development throughout the world. J Clin Oncol 20:47S–59S.
- Shacter, E., Weitzman, S. A. (2002). Chronic inflammation and cancer. Oncology 16:217–226.
- Shen, Z., Peedikayil, J., Olson, G. K., Seibert, P. D., Fang, Y. (2002). Multiple transcription factor profiling by enzyme-linked immunoassay. Biotechniques 32:1168–1177.
- Sprick, M. R., Walczak, H. (2004). The interplay between the Bcl-2 family and death receptor-mediated apoptosis. Biochim Biophys Acta 1644:125–132.
- Tatsuta, T., Chengm, J., Mountz, J. D. (1996). Intracellular IL-1b is an inhibitor of Fas-mediated apoptosis. J Immunol 157:3949.
- Tong, X., Lin, S., Fujii, M., Hou, D. X. (2004). Echinocystic acid induces apoptosis in HL-60 cells through mitochondria-mediated death pathway. Cancer Lett 212:21–32.
- Waxman, D. J., Schwartz, P. S. (2003). Harnessing apoptosis for improved anticancer gene therapy. Cancer Res 63:8563–8572.
- Yadavilli, S., Muganda, P. M. (2004). Diepoxybutane induces caspase- and p53-mediated apoptosis in human lymphoblasts. Toxicol Appl Pharmacol 195:154–165.
- Zhang, S., Won, Y. K., Ong, C. N., Shen, H. M. (2005). Anti-cancer potential of sesquiterpene lactones: bioactivity and molecular mechanisms. Curr Med Chem Anticancer Agents 5:239–249.