220
Views
32
CrossRef citations to date
0
Altmetric
Research Article

Induction of apoptosis by sulforaphane in highly metastatic B16F-10 melanoma cells

, &
Pages 332-340 | Received 19 Sep 2010, Accepted 02 Nov 2010, Published online: 07 Jun 2011

References

  • Adams, J. M., Cory, S. (1998). The Bcl-2 protein family: arbiters of cell survival. Science 281:1322–1326.
  • Aggarwal, B. B. (2004). Nuclear factor-kappaB: the enemy within. Cancer Cell 6:203–208.
  • Aggarwal, B. B., Natarajan, K. (1996). Tumor necrosis factors: developments during the last decade. Eur Cytokine Netw 7:93–124.
  • Angel, P., Karin, M. (1991). The role of Jun, Fos, and the AP-1 complex in cell proliferation and transformation. Biochim Biophys Acta 1072:129–157.
  • Asakage, M, Tsuno, NH, Kitayama, J, Tsuchiya, T, Yoneyama, S, Yamada, J, et al. (2006). Sulforaphane induces inhibition of human umbilical vein endothelial cells proliferation by apoptosis. Angiogenesis 9:83–91.
  • Barkett, M., Gilmore, T. D. (1999). Control of apoptosis by Rel/NF-kappaB transcription factors. Oncogene 18:6910–6924.
  • Beg, A. A., Baltimore, D. (1996). An essential role for NF-kappaB in preventing TNF-alpha–induced cell death. Science 274:782–784.
  • Bhamre, S., Sahoo, D., Tibshirani, R., Dill, D. L., Brooks, J. D. (2009). Temporal changes in gene expression induced by sulforaphane in human prostate cancer cells. Prostate 69:181–190.
  • Bharti, A. C., Donato, N., Singh, S., Aggarwal, B. B. (2003). Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaB alpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. Blood 101:1053–1062.
  • Chipuk, J. E., Green, D. R. (2004). Cytoplasmic p53: bax and forward. Cell Cycle 3:429–431.
  • Cole, S. P. (1986). Rapid chemosensitivity testing of human lung tumor cells using the MTT assay. Cancer Chemother Pharmacol 17:259–263.
  • Dignam, J. D., Lebovitz, R. M., Roeder, R. G. (1983). Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucl Acids Res 11:1475–1489.
  • Elmore, S. (2007). Apoptosis: a review of programmed cell death. Toxicol Pathol 35:495–516.
  • Estrov, Z., Thall, P. F., Talpaz, M., Estey, E. H., Kantarjian, H. M., Andreeff, M., et al. (1998). Caspase-2 and caspase-3 protein levels as predictors of survival in acute myelogenous leukemia. Blood 92:3090–3097.
  • Evan, G. I., Brown, L., Whyte, M., Harrington, E. (1995). Apoptosis and the cell cycle. Curr Opin Cell Biol 7:825–834.
  • Gross, A., McDonnell, J. M., Korsmeyer, S. J. (1999). Bcl-2 family members and the mitochondria in apoptosis. Genes Dev 13:1899–1911.
  • Herr, I., Debatin, K. M. (2001). Cellular stress response and apoptosis in cancer therapy. Blood 98:2603–2614.
  • Huang, C., Chen, N., Ma, W. Y., Dong, Z. (1998). Vanadium induces AP-1- and NFkappB-dependent transcription activity. Int J Oncol 13:711–715.
  • Huang, C., Ma, W. Y., Dong, Z. (1996). Requirement for phosphatidylinositol 3-kinase in epidermal growth factor-induced AP-1 transactivation and transformation in JB6 P+ cells. Mol Cell Biol 16:6427–6435.
  • Karin, M., Delhase, M. (2000). The I kappa B kinase (IKK) and NF-kappa B: key elements of pro-inflammatory signalling. Semin Immunol 12:85–98.
  • Karin, M., Liu, Z., Zandi, E. (1997). AP-1 function and regulation. Curr Opin Cell Biol 9:240–246.
  • Kothakota, S., Azuma, T., Reinhard, C., Klippel, A., Tang, J., Chu, K., et al. (1997). Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science 278:294–298.
  • Lazar-Molnar, E., Hegyesi, H., Toth, S., Falus, A. (2000). Autocrine and paracrine regulation by cytokines and growth factors in melanoma. Cytokine 12:547–554.
  • Li, H., Zhu, H., Xu, C. J., Yuan, J. (1998). Cleavage of Bid by caspase-8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94:491–501.
  • Luo, X., Budihardjo, I., Zou, H., Slaughter, C., Wang, X. (1998). Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94:481–490.
  • Marchenko, N. D., Zaika, A., Moll, U. M. (2000). Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J Biol Chem 275:16202–16212.
  • Martin, S. J., Green, D. R. (1995). Protease activation during apoptosis: death by a thousand cuts? Cell 82:349–352.
  • Moon, D. O., Kim, M. O., Kang, S. H., Choi, Y. H., Kim, G. Y. (2009). Sulforaphane suppresses TNF-alpha–mediated activation of NF-kappaB and induces apoptosis through activation of reactive oxygen species–dependent caspase-3. Cancer Lett 274:132–142.
  • Pradeep, C. R., Kuttan, G. (2004). Piperine is a potent inhibitor of nuclear factor-kappaB (NF-kappaB), c-Fos, CREB, ATF-2, and pro-inflammatory cytokine gene expression in B16F-10 melanoma cells. Int Immunopharmacol 4:1795–1803.
  • Saez, E., Rutberg, S. E., Mueller, E., Oppenheim, H., Smoluk, J., Yuspa, S. H., et al. (1995). c-fos is required for malignant progression of skin tumors. Cell 82:721–732.
  • Sakahira, H., Enari, M., Nagata, S. (1998). Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391:96–99.
  • Sekine-Suzuki, E., Yu, D., Kubota, N., Okayasu, R., Anzai, K. (2008). Sulforaphane induces DNA double strand breaks predominantly repaired by homologous recombination pathway in human cancer cells. Biochem Biophys Res Commun 377:341–345.
  • Thejass, P., Kuttan, G. (2006a). Anti-metastatic activity of sulforaphane. Life Sci 78:3043–3050.
  • Thejass, P., Kuttan, G. (2006b). Augmentation of natural killer cell and antibody-dependent cellular cytotoxicity in BALB/c mice by sulforaphane, a naturally occurring isothiocyanate from broccoli through enhanced production of cytokines IL-2 and IFN-gamma. Immunopharmacol Immunotoxicol 28:443–457.
  • Thornberry, N. A., Lazebnik, Y. (1998). Caspases: enemies within. Science 281:1312–1316.
  • Tripathi, P., Aggarwal, A. (2006). Regulation of NF-kB. Curr Sci 90:519–531.
  • Vandenabeele, P., Declercq, W., Beyaert, R., Fiers, W. (1995). Two tumor necrosis factor receptors: structure and function. Trends Cell Biol 5:392–399.
  • Wang, X. (2001). The expanding role of mitochondria in apoptosis. Genes Dev 15:2922–2933.
  • Wei, L. H., Kuo, M. L., Chen, C. A., Chou, C. H., Lai, K. B., Lee, C. N., et al. (2003). Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway. Oncogene 22:1517–1527.
  • Zhong, H., Voll, R. E., Ghosh, S. (1998). Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol Cell 1:661–671.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.