The influence of curcumin and (–)-epicatechin on the genotoxicity and myelosuppression induced by etoposide in bone marrow cells of male rats

References

• Alaikov, T., Konstantinov, S. M., Tzanova, T., Dinev, K., Topashka-Ancheva, M., Berger, M. R. (2007). Antineoplastic and anticlastogenic properties of curcumin. Ann N Y Acad Sci 1095:355–370.
   PubMed Web of Science ®Google Scholar
• Antunes, L. M., Araújo, M. C., Darin, J. D., Bianchi, M. L. (2000). Effects of the antioxidants curcumin and vitamin C on cisplatin-induced clastogenesis in Wistar rat bone marrow cells. Mutat Res 465:131–137.
   PubMed Web of Science ®Google Scholar
• Corbett, A. H., Osheroff, N. (1993). When good enzymes go bad: conversion of topoisomerase II to a cellular toxin by antineoplastic drugs. Chem Res Toxicol 6:585–597.
   PubMed Web of Science ®Google Scholar
• Cuevas, E., Limon, D., Perez-Severiano, F., Diaz, A., Ortega, L. (2009). Antioxidant effects of epicatechin on the hippocampal toxicity caused by amyloid-beta 25–35 in rats. Eur J Pharmacol 616:122–127.
   PubMed Web of Science ®Google Scholar
• Enomoto, R., Koshiba, C., Suzuki, C., Lee, E. (2011). Wogonin potentiates the antitumor action of etoposideand ameliorates its adverse effects. Cancer Chemother Pharmacol 67:1063–1072.
   PubMed Web of Science ®Google Scholar
• Er, T. K., Tsai, S. M., Wu, S. H., Chiang, W., Lin, H. C., Lin, S. F., et al. (2007). Antioxidant status and superoxide anion radical generation in acute myeloid leukemia. Clin Biochem 40:1015–1019.
   PubMed Web of Science ®Google Scholar
• Fan, Y., Schreiber, E. M., Giorgianni, A., Yalowich, J. C., Day, B. W. (2006). Myeloperoxidase-catalyzed metabolism of etoposide to its quinone and glutathione adduct forms in HL60 cells. Chem Res Toxicol 19:937–943.
   PubMed Web of Science ®Google Scholar
• Feng, R., Ni, H. M., Wang, S. Y., Tourkova, I. L., Shurin, M. R., Harada, H. (2007). Cyanidin-3-rutinoside, a natural polyphenol antioxidant, selectively kills leukemia cells by induction of oxidative stress. J Biol Chem 282:13468–13476.
   PubMed Web of Science ®Google Scholar
• Fraga, C. G. (2007). Plant polyphenols: how to translate their in vitro antioxidant actions to in vitro conditions. IUBMB Life 59:308–315.
   PubMed Web of Science ®Google Scholar
• Goel, A. (2010). Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs. Nutr Cancer 62:919–930.
   PubMed Web of Science ®Google Scholar
• Haim, N., Nemec, J., Roman, J., Sinha, B. (1987). Peroxidase-catalyzed metabolism of etoposide (VP-16–213) and covalent binding of reactive intermediates to cellular macromolecules. Cancer Res 47:5835–5840.
   PubMed Web of Science ®Google Scholar
• Hanasaki, Y., Ogawa, S., Fukui, S. (1994). The correlation between active oxygens scavenging and antioxidative effects of flavonoids. Free Radic Biol Med 16:845–850.
   PubMed Web of Science ®Google Scholar
• Hande, K. R. (1992). Etoposide pharmacology. Semin Oncol 19:3–9.
   PubMed Web of Science ®Google Scholar
• Iqbal, M., Okazaki, Y. (2009). Curcucmin attenuates oxidative damage in animals treated with a renal carcinogen, ferric nitrilotriacetate (Fe-NTA): implications from cancer prevention. Mol Cell Biochem 324:157–164.
   PubMed Web of Science ®Google Scholar
• Joel, S. P., Shah, R., Slevin, M. L. (1994). Etoposide dosage and pharmacodynamics. Cancer Chemother Pharmacol 34:S69–S75.
   PubMed Web of Science ®Google Scholar
• Kagan, V. E., Kuzmenko, A.I., Tyurina, Y. Y., Shvedova, A. A., Matsura, T., Yalowich, J. C. (2001). Prooxidant and antioxidant mechanisms of etoposide in HL-60 cells: role of myeloperoxidase. Cancer Res 61:7777–7784.
   PubMed Web of Science ®Google Scholar
• Kagan, V. E., Yalowich, J. C., Borisenko, G. G., Tyurina, Y. Y., Tyurin, V. A., Thampatty, P., et al. (1999). Mechanism-based chemopreventive strategies against etoposide-induced acute myeloid leukemia: free radical/antioxidant approach. Mol Pharmacol 56:494–506.
   PubMed Web of Science ®Google Scholar
• Kamiya, H., Miura, K., Ishikawa, H., Inoue, H., Nishimura, S., Ohtsuka, E. (1992). c-Ha-ras containing 8-hydroxyguanine at codon 12 induces point mutations at the modified and adjacent positions. Cancer Res 52:3483–3485.
   PubMed Web of Science ®Google Scholar
• Kapiszewska, M., Cierniak, A., Papież, M. A., Pietrzycka, A., Stępniewski, M., Łomnicki, A. (2007). Prolonged quercetin administration diminishes the etoposide-induced DNA damage in bone marrow cells of rats. Drug Chem Toxicol 30:67–81.
   PubMed Web of Science ®Google Scholar
• Karanjawala, Z. E., Murphy, N., Hinton, D. R., Hsieh, C. L., Lieber, M. R. (2002). Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants. Curr Biol 12:397–402.
   PubMed Web of Science ®Google Scholar
• Kelkel, M., Jacob, C., Dicato, M., Diederich, M. (2010). Potential of the dietary antioxidants resveratrol and curcumin in prevention and treatment of hematologic malignancies. Molecules 15:7035–7074.
   PubMed Web of Science ®Google Scholar
• Kobayashi, K., Ratain, M. J. (1994). Pharmacodynamics and long-term toxicity of etoposide. Cancer Chemother Pharmacol 34:S64–S68.
   PubMed Web of Science ®Google Scholar
• Kuhad, A., Pilkhwal, S., Sharma, S., Tirkey, N., Chopra, K. (2007). Effect of curcumin on inflammation and oxidative stress in cisplatin-induced experimental nephrotoxicity. J Agric Food Chem 55:10150–10155.
   PubMed Web of Science ®Google Scholar
• Lyu, B. N., Ismailov, S. B., Ismailov, B., Lyu, M. B. (2008). Mitochondrial concept of leukemogenesis: key role of oxygen-peroxide effects. Theor Biol Med Modelling 11:5–23.
   Google Scholar
• Marnett, L. J. (1999). Lipid peroxidation-DNA damage by malonodialdehyde. Mut Res 424:83–95.
   PubMed Web of Science ®Google Scholar
• Mohamed, R. H., Karam, R. A., Amer, M. G. (2011). Epicatechin attenuates doxorubicin-induced brain toxicity: critical role of TNF-α, iNOS, and NF-κB. Brain Res Bull 86:22–28.
   PubMed Web of Science ®Google Scholar
• Naidu, K. A., Thippeswamy, N. B. (2002). Inhibition of human low density lipoprotein oxidation by active principles from spices. Mol Cell Biochem 229:19–23.
   PubMed Web of Science ®Google Scholar
• Papież, M. A., Baran, J., Bukowska-Straková, K., Wiczkowski, W. (2010). Antileukemic action of (–)-epicatechin in the spleen of rats with acute myeloid leukemia. Food Chem Toxicol 48:3391–3397.
   PubMed Web of Science ®Google Scholar
• Papież, M. A., Dybała, M., Sowa-Kućma, M., Krzyściak, W., Taha, H., Józkowicz, A., et al. (2009). Evaluation of oxidative status and depression-like responses in Brown Norway rats with acute myeloid leukemia. Prog Neuropsychopharmacol Biol Psychiatry 33:596–604.
   PubMed Web of Science ®Google Scholar
• Reddy, A. C., Lokesh, B. R. (1994). Studies on the inhibitory effects of curcumin and eugenol on the formation of reactive oxygen species and the oxidaton of ferrous ion. Mol Cell Biochem 137:1–8.
   PubMed Web of Science ®Google Scholar
• Rzeszutko, W., Wróbel, T., Mazur, G., Rzeszutko, M., Dzięgiel, P., Pyszel, A., et al. (2006). Effect of exogenous melatonin on rat haematopoietic cells exposed to cytosine arabinoside and etoposide. Adv Clin Exp Med 15:979–982.
   Google Scholar
• Sallmyr, A., Fan, J., Rassool, F. V. (2008). Genomic instability in myeloid malignancies: increased reactive oxygen species (ROS), DNA double strand breaks (DSBs), and error-prone repair. Cancer Lett 270:1–9.
   PubMed Web of Science ®Google Scholar
• Schumacker, P. T. (2006). Reactive oxygen species in cancer cells: live by the sword, die by the sword. Cancer Cell 10:175–176.
   PubMed Web of Science ®Google Scholar
• Shibutani, S., Takeshita, M., Grollman, A. P. (1991). Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature 349:431–434.
   PubMed Web of Science ®Google Scholar
• Shukla, Y., Arora, A., Taneja, P. (2002). Antimutagenic potential of curcumin on chromosomal aberrations in Wistar rats. Mutat Res 515:197–202.
   PubMed Web of Science ®Google Scholar
• Siddique, Y. H., Ara, G., Beg, T., Gupta, J., Afzal, M. (2010). Assessment of cell viability, lipid peroxidation and quantification of DNA fragmentation after the treatment of anticancerous drug mitomycin C and curcumin in cultured human blood lymphocytes. Exp Toxicol Pathol 62:503–508.
   PubMed Web of Science ®Google Scholar
• Slevin, M. L. (1991). The clinical pharmacology of etoposide. Cancer 67:319–329.
   PubMed Web of Science ®Google Scholar
• Smith, M. A., Rubinstein, L., Cazenova, L., Ungerleider, R. S., Maurer, H. M., Heyn, R., et al. (1993). Report of the cancer therapy evaluation program monitoring plan for secondary acute myeloid leukemia following treatment with epidopodophyllotoxins. J Natl Cancer Inst 85:554–558.
   PubMed Web of Science ®Google Scholar
• Takano, F., Tanaka, T., Aoi, J., Yahagi, N., Fushiya, S. (2004). Protective effect of (+)-catechin against 5-fluorouracil-induced myelosuppression in mice. Toxicology 201:133–142.
   PubMed Web of Science ®Google Scholar
• Tice, R. R., Andrews, P. W., Hirai, O., Singh, N. P. (1991). The single cell gel (SCG) assay: an electrophoretic technique for the detection of DNA damage in individual cells. Adv Exp Med Biol 283:157–164.
   PubMedGoogle Scholar
• Turner, S. D., Wijnhoven, S. W. P., Tinwell, H., Lashford, L. S., Rafferty, J. A., Ashby, J., et al. (2001). Assays to predict the genotoxicity of the chromosomal mutagen etoposide—focusing on the best assay. Mutat Res 493:139–147.
   PubMed Web of Science ®Google Scholar
• Venkatesan, N. (1998). Curcumin attenuation of acute adriamycin myocardial toxicity in rats. Br J Pharmacol 124:425–427.
   PubMed Web of Science ®Google Scholar
• Vlasova, I. I., Feng, W., Goff, J. P., Giorgianni, A., Do, D., Gollin, S. M., et al. (2011). Myeloperoxidase-dependent oxidation of etoposide in human myeloid progenitor CD34+ cells. Mol Pharmacol 79:479–487.
   PubMed Web of Science ®Google Scholar
• Whitlock, J. A., Greer, J. P., Lukens, J. N. (1991). Epipodophyllotoxin-related leukemia. Identification of a new subset of secondary leukemia. Cancer 68:600–604.
   PubMed Web of Science ®Google Scholar
• Yamamoto, T., Hsu, S., Lewis, J., Wataha, J., Dickinson, D., Singh, B., et al. (2003). Green tea polyphenol causes differential oxidative environments in tumor versus normal epithelial cells. J Pharmacol Exp Ther 307:230–236.
   PubMed Web of Science ®Google Scholar
• Yang, Y., Jin, X. M., Yan, C. H., Tian, Y., Tang, J. Y., Shen, X. M. (2008). Urinary level of nickel and acute leukaemia in Chinese children. Toxicol Ind Heath 24:603–610.
   PubMed Web of Science ®Google Scholar
• Yang, Y., Tian, Y., Yan, C., Jin, X., Tang, J., Shen, X. (2009). Determinants of urinary 8-hydroxy-2′-deoxyguanosine in Chinese children with acute leukemia. Environ Toxicol 24:446–452.
   PubMed Web of Science ®Google Scholar
• Zhou, F. I., Zhang, W. G., Wie, Y. C., Meng, S., Bai, G. G., Wang, B. Y., et al. (2010). Involvement of oxidative stress in the relapse of acute myeloid leukaemia. J Biol Chem 285:15010–15015.
   PubMed Web of Science ®Google Scholar
• Zhou, F., Zhang, W., Wie, Y., Zhou, D., Su, Z., Meng, X., et al. (2007). The changes of oxidative stress and human 8-hydroxyguanine glycosylase 1 gene expression in depressive patients with acute leukemia. Leukemia Res 31:387–393.
   PubMed Web of Science ®Google Scholar
• Zhou, Q. M., Zhang, H., Lu, Y. Y., Wang, X. F., Su, S. B. (2009). Curcumin reduced the side effects of mitomycin C by inhibiting GRP58-mediated DNA cross-linking in MCF-7 breast cancer xenografts. Cancer Sci 100:2040–2045.
   PubMed Web of Science ®Google Scholar