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Research Article

The Lack of Effect of Tertiary Butylhydroquinone on Prothrombin Time in Male Rats

Pages 329-334 | Published online: 27 Sep 2008

References

  • Federal Register (1972); 37(231)25356, BHT - 21 CRF 172.115 and 21 CRF 182.3173. TBHQ - 21 CFR 121.1244 (Recodified March 1977 to 21 CFR 172.185.)
  • Takahashi O., Hiraga K. Dose-response study of hemorrhagic death by dietary butylated hydroxytoluene (BHT) in male rats. Toxicol. Appl. Pharmacol. (1978); 43: 399
  • Takahashi O., Hyashida S., Uiraga K. Species differences in the hemorrhagic response to butylated hydroxytoluene. Fd. Cosmet. Toxicol. (1980); 18: 229
  • Takahashi O., Hiraga K. Preventive effects of phylloquinone on hemorrhagic death induced by butylated hydroxytoluene in male rats. J. Nutr. (1979); 109: 453
  • Takahashi O., Hiraga K. The relationship between hemorrhage induced by butylated hydroxytoluene and its antioxidant properties or structural characteristics. Toxicol. Appl. Pharmacol. (1978); 46: 811
  • Takahashi O., Hiraga K. 4–tert-Butyl-2,6–diisopropyl-phenol: another phenol producing hemorrhage in rats. Toxicol. Lett. (1980); 5: 147
  • Takahashi O., Hiraga K. Effects of four bisphenolic antioxidants on prothrombin levels of rat plasma. Toxicol. Lett. (1981); 7: 405
  • Toxicological Sciences, Health and Environment Laboratories, Eastman Kodak Company. (1982), Attempts to induce hemorrhagic death in male rats with butylated hydroxytoluene (BAT): Probe Studies. Report 134788y, TX82–14
  • Quick A. J., Stanley-Brown M., Bancroft F. W. A study of the coagulation defect in hemophilia and in jaundice. Am. J. Med. Sci. (1935); 190: 501
  • Tertiary butyl hydroquinone (TBHQ). Prothrombin times in male rats -A preliminary study. Toxicological Sciences, Health and Environment Laboratories, Eastman Kodak Company. (1982), Report 134785v TX82–11
  • Quick A. J. The prothrombin time on hemophilia and in obstructive jaundice. J. Biol. Chem. (1935); 109: 73

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