Publication Cover
Archives of Andrology
Journal of Reproductive Systems
Volume 8, 1982 - Issue 4
193
Views
40
CrossRef citations to date
0
Altmetric
Original Article

Ultrastructural Studies of Spermatozoa and the Epithelial Lining of the Epididymis and Vas Deferens in Rats Treated with Gossypol

Pages 233-246 | Received 09 Feb 1982, Published online: 09 Jul 2009

References

  • Abou-Donia M B. Physiological effects and metabolism of gossypol. Residue Rev 1976; 61: 125–160
  • Abou-Donia M B, Dieckert J W. Gossypol: Uncoupling of respiratory chain and oxidative phosphorylation. Life Sci 1974; 14: 1955–1963
  • Blanco A. On the functional significance of LDH-x. The Johns Hopkins Med J 1980; 146: 231–235
  • Bozek S A, Jensen D R, Tone J N. Scanning electron microscopic study of spermatozoa from gossypol-treated rats. Cell Tissue Res 1981; 219: 659–663
  • Chang M C, Gu Z, Saksena S. Effects of gossypol on the fertility of male rats, hamsters and rabbits. Contraception 1980; 21: 461–469
  • Coulson P B, Sneil R, Parise C. In vitro effects of the antifertility agent, gossypol, on the reproductive organs in male mice. Int J Androl 1980; 3: 507–518
  • Coutinho E, Segal S, Melo J F. Biphasic action of gossypol in men. 1982, Personal communication
  • Gallup W D, Reder R. The influence of certain dietary constituents on the response of rats to gossypol ingestion. J Agr Res 1935; 51: 259–266
  • Hadley M, Lin T, Dym M. Effects of gossypol on the reproduction system of male rats. J Androl 1981; 2: 190–199
  • Hahn D W, Rusticus C, Probst A, Homm R. Antifertility and endocrine activities of gossypol in rodents. Contraception 1981; 24: 97–105
  • Hamilton D W. The mammalian epididymis. Biology of Reproduction, H Balin, S Glasser. Excerpta Medica Foundation, Amsterdam 1972; 268–337
  • Hoffer A P, Hamilton D W, Fawcett D W. The ultrastructure of principal cells and intraepithelial leucocytes in the initial segment of the rat epididymis. Anat Rec 1973; 175: 169–202
  • Hoffer A P. Light and electron microscopic studies on the effects of gossypol in the male ra. Gossypol—A Possible Male Antifertility Agent: Report of a Workshop, G Zatuchni, C Osborn. Research Frontiers in Fertility Regulation, PARFR, Chicago, IL 1980; vol 1: 1981
  • Jackson H. Comparative effects of some antispermatogenic chemicals. The Regulation of Mammalian Reproduction, S Segal, R Crozier, P Corfman, P Condliffe. Thomas, Springfield, IL 1973; 257–272
  • Lee Chi-Yu, Malling H V. Selective inhibition of sperm-specific lactate dehydrogenase-x by an anti-fertility agent, gossypol. Fed Proc 1981; 40: 718a
  • Nadakavukaren M, Sorensen R H, Tone J N. Effect of gossypol on the ultrastructure of rat spermatozoa. Cell Tissue Res 1979; 204: 293–296
  • National Coordinating Group for Male Contraceptives. Gossypol—A new antifertility agent for males. Chinese Med J 1978; 4: 417–428
  • Pösö H, Wichmann K, Jänne J, Luukkainen T. Gossypol, a powerful inhibitor of human spermatozoal metabolism. The Lancet 1980; 1: 885–886
  • Prasad M RN, Diczfalusy E (1982) Gossypol. Second International Congress of Andrology. Proceedings of Symposium held in Tel Aviv. June, 1981, In press
  • Venable J H, Coggeshall R. A simplified lead citrate stain for use in electron microscopy. J Cell Biol 1965; 25: 407–408
  • Watson M. Staining of tissue sections for electron microscopy with heavy metal. J Biophys Biochem Cytol 1958; 4: 475–478
  • Zatuchni G I. Gossypol: a possible male antifertility agent: Report of a Workshop. Research Frontiers in Fertility Regulation 1981; 1: 1–15

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.