The Effect of Cerebellar Midline Lesions on Eye Movements

References

• Leigh R. J., Zee D. S. The Neurology of Eye Movements, 2nd edn. Contemporary Neurology Series, FA Davis Co, Philadelphia 1991; Vol. 35
   Google Scholar
• Zee D. S., Yamazaki A., Butler P. H., Gücer G. Effects of ablation of flocculus and parafiocculus on eye movements in primates. J Neuro-physiol 1981; 46: 878–899
   Google Scholar
• Waespe W., Cohen B., Raphan Th. Dynamic modification of the vesti-bulo-ocular reflex by the nodulus and uvula. Science 1985; 228: 199–202
   PubMed Web of Science ®Google Scholar
• Bötzel K., Rottach K., Büttner U. Normal and pathological saccadic dysmetria. Brain 1993; 116: 337–353
   Google Scholar
• Kurzan R., Straube A., Büttner U. The effect of Muscimol microinjections into the fastigial nucleus on the optokinetic response and the vestibulo-ocular reflex in the alert monkey. Exp Brain Res 1993; 94: 252–260
   Google Scholar
• Kase M., Miller D. C., Noda H. Discharges of Purkinje cells and mossy fibres in the cerebellar vermis of the monkey during saccadic eye movements and fixation. J Physiol (London) 1980; 300: 539–555
   Google Scholar
• Suzuki D. A., Keller E. L. The role of the posterior vermis of monkey cerebellum in smooth pursuit eye movement control. II. Target velocity-related Purkinje cell activity. J Neurophysiol 1988; 59: 19–40
   PubMedGoogle Scholar
• Aschoff J. C., Cohen B. Changes in saccadic eye movements produced by cerebellar cortical lesions. Exp Neurol 1971; 32: 123–133
   PubMed Web of Science ®Google Scholar
• Ritchie L. Effects of cerebellar lesions on saccadic eye movements. J Neurophysiol 1976; 39: 1246–1256
   PubMed Web of Science ®Google Scholar
• Keller E. L. Cerebellar involvement in smooth pursuit eye movement generation flocculus and vermis. Chapman and Hall, C. Kennard, F. Clifford Rose. Physiological Aspects of Clinical Neuro-Ophthalmology, London 1988; 341–354
   Google Scholar
• Pierrot-Deseilligny Ch., Amarenco P., Roullet E., Marteau R. Vermal infarct with pursuit eye movement disorders. J Neurol Neurosurg Psychiat 1990; 53: 519–521
   PubMedGoogle Scholar
• Herbst H., Thier P., Dichgans J., Petersen D. Deficit of smooth-pursuit eye movements in patients with extra-floccular cerebellar lesions. Proc Xth Neuro-Ophthalmol Soc Meeting, Freiburg 1994; P42
   Google Scholar
• Yamada J., Noda H. Afferent and efferent connections of the oculomotor cerebellar vermis in the macaque monkey. J Comp Neurol 1987; 265: 224–241
   PubMed Web of Science ®Google Scholar
• Fuchs A. F., Robinson F. R., Straube A. Role of the caudal fastigial nucleus in saccade generation. I. Neuronal discharge patterns. J Neurophysiol 1993; 70: 1723–1740
   PubMed Web of Science ®Google Scholar
• Helmchen Ch., Straube A., Büttner U. Saccadic activity in the fastigial oculomotor region of the macaque monkey during spontaneous eye movements in light and darkness. Exp Brain Res 1994; 98: 474–482
   Google Scholar
• Büttner U., Fuchs A. F., Markert-Schwab G., Buckmaster P. Fastigial nucleus activity in the alert monkey during slow eye and head movements. J Neurophysiol 1991; 65: 1360–1371
   PubMedGoogle Scholar
• Fuchs A. F., Robinson F. R., Straube A. Discharge of simian caudal fastigial nucleus neurons during smooth-pursuit eye movements. Contemporary Ocular Motor and Vestibular Research: A Tribute to David A. Robinson. Stuttgart: Georg Thieme Verlag (in press), D. Zee, U. Büttner, A. Fuchs, Th Brandt
   Google Scholar
• Kommerell G., Hoyt W. F. Lateropul-sion of saccadic eye movements. Arch Neurol 1973; 28: 313–318
   PubMedGoogle Scholar
• Robinson F. R., Straube A., Fuchs A. F. Role of the caudal fastigial nucleus in saccade generation. II. Effects of muscimol inactivation. J Neurophysiol 1993; 70: 1741–1758
   PubMed Web of Science ®Google Scholar
• Robinson F. R., Straube A., Fuchs A. F. Smooth pursuit deficits after muscimol inactivation of the caudal fastigial nucleus in Macaque. Soc Neurosci Abstr 1994; 20(1): 858
   Google Scholar
• Cohen B., Matsuo V., Raphan T. Quantitative analysis of the velocity characteristics of optokinetic nystagmus and optokinetic after-nystagmus. J Physiol 1977; 270: 321–344
   PubMed Web of Science ®Google Scholar
• Dichgans J., VonReutern G. M., Rommelt U. Impaired suppression of vestibular nystagmus by fixation in cerebellar and non-cerebellar patients. Arch Psychiat Nervenkr 1978; 226: 183–199
   PubMedGoogle Scholar
• Optican L. M., Robinson D. A. Cerebel-lar-dependent adaptive control of the primate saccadic system. J Neuro-physiol 1980; 44: 1058–1075
   Google Scholar
• Büttner U., Straube A., Spuler A. Saccadic dysmetria and ‘intact’ smooth pursuit eye movements after bilateral deep cerebellar nuclei lesions. J Neurol Neurosurg Psychiat 1994; 57: 832–834
   Google Scholar
• Noda H., Sugita S., Ikeda Y. Afferent and efferent connections of the oculomotor region of the fastigial nucleus in the Macaque monkey. J Comp Neurol 1990; 302: 330–348
   PubMed Web of Science ®Google Scholar
• Ranalli P. J., Sharpe J. A. Contrapulsion of saccades and ipsilateral ataxia: A unilateral disorder of the rostral cerebellum. Ann Neurol 1986; 20: 311–316
   PubMed Web of Science ®Google Scholar
• Straube A., Büttner U. Pathophysiology of saccadic contrapulsion in unilateral rostral cerebellar lesions. Neuro-ophfhalmology 1994; 14: 3–7
   Web of Science ®Google Scholar
• Uno A., Mukuno K., Sekiya H., Ishikawa S., Suzuki S., Hata T. Lateropulsion in Wallenberg's syndrome and contrapulsion in the proximal type of the superior cerebellar artery syndrome. Neuro-ophthal-mology 1989; 9: 75–80
   Web of Science ®Google Scholar
• Ito M. The Cerebellum and Neural Control. Raven Press, New York 1984
   Google Scholar
• Büttner U., Büttner-Ennever J. A. Present concepts of oculomotor organization. Neuroanatomy of the Oculomotor System. Reviews of Oculomotor Research, J A Büttner-Ennever. Elsevier, Amsterdam 1988; Vol 2: 3–32
   Google Scholar
• Langer T., Fuchs A. F., Scudder C. A., Chubb M. C. Afferents to the flocculus of the cerebellum in the rhesus macaque as revealed by retrograde transport of horseradish peroxidase. J Comp Neurol 1985; a: 235: 1–25
   Google Scholar
• Langer T., Fuchs A. F., Chubb M. C., Scudder C. A., Lisberger S. G. Floccular efferents in the rhesus macaque as revealed by autoradiography and horseradish peroxidase. J Comp Neurol 1985b; 235: 26–37
   PubMedGoogle Scholar
• Selhorst J. B., Stark L., Ochs A. L., Hoyt W. F. Disorders in cerebellar ocular motor control. II. Macrosaccadic oscillation: An oculographic, control system and clinico-anatomical analysis. Brain 1976b; 99: 509–522
   PubMed Web of Science ®Google Scholar
• Helmchen Ch., Straube A., Büttner U. Saccadic lateropulsion in Wallenberg's syndrome may be caused by a functional lesion of the fastigial nucleus. J Neurol 1994; 241: 421–426
   PubMed Web of Science ®Google Scholar
• Straube A., Helmchen Ch., Robinson F., Fuchs A., Büttner U. Saccadic dysmetria is similar in patients with a lateral medullary lesion and in monkeys with a lesion of the deep cerebellar nucleus. J Vestibular Res 1994; 4: 327–333
   Google Scholar
• Waespe W., Wichmann W. Oculomotor disturbances during visual-vestib-ular interaction in Wallenberg's lateral medullary syndrome. Brain 1990; 113: 821–846
   PubMed Web of Science ®Google Scholar
• Demer J. L., Echelman D. A., Robinson D. A. Effects of electrical stimulation and reversible lesions of the olivocerebellar pathway on Purkinje cell activity in the flocculus of the cat. Brain Res 1985; 346: 22–31
   Google Scholar
• Henn V., Lang W., Hepp K., Reisine H. Experimental gaze palsies in monkeys and their relation to human pathology. Brain 1984; 107: 619–636
   PubMed Web of Science ®Google Scholar
• Selhorst J. B., Stark L., Ochs A. L., Hoyt W. F. Disorders in cerebellar ocular motor control. I. Saccadic overshoot dysmetria, an oculographic, control system and clinico-anatomic analysis. Brain 1976; 99: 497–508
   PubMed Web of Science ®Google Scholar
• Straube A., Deubel H., Spuler A., Büttner U. Differential effect of a bilateral deep cerebellar nuclei lesion on externally and internally triggered saccades in humans. Neuro-ophthal-mology, (submitted).
   Google Scholar
• Hepp K., Henn V., Jaeger J. Eye movement related neurons in the cerebellar nuclei of the alert monkey. Exp Brain Res 1982; 45: 253–261
   PubMedGoogle Scholar