Up-regulation of cyclin D1 expression in asthma serum-sensitized human airway smooth muscle promotes proliferation via protein kinase Cα

REFERENCES

• Beasley R, Crane J, Lai CK, Pearce N: Prevalence and etiology of asthma. J Allergy Chin Immunol. 2000;10S:S466–S472.
   Google Scholar
• Masoli M, Fabian D, Holt S, Beasley R: The global burden of asthma: executive summary of the GINA dissemination committee report. Allergy. 2004;59:467–478.
   Google Scholar
• Chung KF: Airway smooth muscle cells: contributing to and regulating airway mucosal inflammation? Eur Respir J. 2000;15:961–968.
   PubMed Web of Science ®Google Scholar
• Elias JA, Zhu Z, Chupp G, Homer RJ: Airway remodeling in asthma. J Clin Invest. 1999;104:1001–1006.
   PubMed Web of Science ®Google Scholar
• Fredberg JJ: Airway smooth muscle in asthma. Perturbed equilibria of myosin binding. Am J Respir Crit Care Med. 2000;161:158S–160S.
   PubMed Web of Science ®Google Scholar
• Que CL, Maksym G, Macklem PT: Deciphering the homeokinetic code of airway smooth muscle. Am J Respir Crit Care Med. 2000;161:161S–163S.
   PubMed Web of Science ®Google Scholar
• Webb BL, Lindsay MA, Barnes PJ, Giembycz MA: Protein kinase C isoenzymes in airway smooth muscle. Biochem J. 1997;324:167–175.
   PubMed Web of Science ®Google Scholar
• Dempsey EC, Newton AC, Mochly-Rosen D, Fields AP, Reyland ME, Insel PA, Messing RO: Protein kinase C isozymes and the regulation of diverse cell responses. Am J Physiol Lung Cell Mol Physiol. 2000;279:L429–L438.
   PubMed Web of Science ®Google Scholar
• Parker PJ, Murray-Rust J: PKC at a glance. J Cell Sci. 2004;117:131–132.
   PubMed Web of Science ®Google Scholar
• Michie AM, Nakagawa R: The link between PKCalpha regulation and cellular transformation. Immunol Lett. 2005;96:155–162.
   PubMed Web of Science ®Google Scholar
• Panettieri RA, Rubinstein NA, Kelly AM, Kotlikoff MI: The specificity of c-fos expression in the induction of airway smooth muscle proliferation by contractile agonists. Am Rev Respir Dis. 1991;143:A934.
   Google Scholar
• Lew DB, Brown ER, Dempsey K, Wright HM, Malik KU: Contribution of PKC to β-hexosaminidase-induced airway smooth muscle proliferation. Am J Physiol. 1997;272:L639–L643.
   PubMed Web of Science ®Google Scholar
• Hirst SJ, Barnes PJ, Twort CHC: Differential proliferation of rabbit tracheal smooth muscle by PDGF isoforms: inhibition by selective inhibitors of protein kinase and protein tyrosine kinase. Br J Pharmacol. 1994;112:81P.
   PubMedGoogle Scholar
• Hirst SJ, Barnes PJ, Twort CHC: Protein kinase inhibitors (PKC and PTK) inhibit PDGF isoform-stimulated proliferation of human and rabbit airway smooth muscle. Am J Respir Crit Care Med. 1995;151:A46.
   Google Scholar
• Hirst SJ, Webb BL, Giembycz MA, Barnes PJ, Twort CH: Inhibition of fetal calf serum-stimulated proliferation of rabbit cultured tracheal smooth muscle cells by selective inhibitors of protein kinase C and protein tyrosine kinase. Am J Respir Cell Mol Biol. 1995;12:149–161.
   PubMed Web of Science ®Google Scholar
• Acs P, Wang QJ, Bögi K, Marquez AM, Lorenzo PS, Biro T, Szallasi Z, Muchinski JF, Blumberg PM: Both the catalytic and regulatory domains of protein kinase C chimeras modulate the proliferative properties of NIH 3T3 cells. J Biol Chem. 1997;272:28793–28799.
   PubMed Web of Science ®Google Scholar
• Fukumoto S, Nishizawa Y, Hosoi M, Koyama H, Yamakawa K, Ohno S, Morii H: Protein kinase C delta inhibits the proliferation of vascular smooth muscle by suppressing G1 cyclin expression. J Biol Chem. 1997;272:13816–13822.
   PubMed Web of Science ®Google Scholar
• Harrington EO, Loffler J, Nelson PR, Kent KC, Simons M, Ware JA: Enhancement of migration by protein kinase C alpha and inhibition of proliferation and cell cycle progression by protein kinase C delta in capillary endothelial cells. J Biol Chem. 1997;272:7390–7397.
   PubMed Web of Science ®Google Scholar
• Perletti GP, Marras E, Concari P, Piccinini F, Tashjian AH Jr: PKC delta acts as a growth and tumor suppressor in rat colonic epithelial cells. Oncogene. 1999;18:1251–1256.
   PubMed Web of Science ®Google Scholar
• Page K, Li J, Corbit KC, Rumilla KM, Soh JW, Weinstein IB, Albanese C, Pestell RG, Rosner MR, Hershenson MB: Regulation of airway smooth muscle cyclin D1 transcription by protein kinase C-δ. Am J Respir Cell Mol Biol. 2002;27:204–213.
   PubMed Web of Science ®Google Scholar
• Xu SY, Xu YJ, Zhang ZX, Ni W, Chen SX: Contribution of protein kinase C to passively sensitized human airway smooth muscle cells proliferation. Chin Med J (Engl). 2004;117:30–36.
   PubMed Web of Science ®Google Scholar
• Hirst SJ, Walker TR, Chilvers ER: Phenotypic diversity and molecular mechanisms of airway smooth muscle proliferation in asthma. Eur Respir J. 2000;16:159–177.
   PubMed Web of Science ®Google Scholar
• Albanese C, Johnson J, Watanabe G, Eklund N, Vu D, Arnold A, Pestell RG.: Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions. J Biol Chem. 1995;270:23589–23597.
   PubMed Web of Science ®Google Scholar
• Shtutman M, Zhurinsky J, Simcha I, Albanese C, D’Amico M, Pestell R, Ben-Ze’ev A: The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway. Proc Natl Acad Sci U S A. 1999;96:5522–5527.
   PubMed Web of Science ®Google Scholar
• Ammit AJ, Hastie AT, Edsall LC, Hoffman RK, Amrani Y, Krymskaya VP, Kane SA, Peters SP, Penn RB, Spiegel S, Panettieri RA Jr: Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma. FASEB J. 2001;15:1212–1214.
   PubMed Web of Science ®Google Scholar
• Amrani Y, Tliba O, Choubey D, Huang CD, Krymskaya VP, Eszterhas A, Lazaar AL, Panettieri RA Jr: IFN-gamma inhibits human airway smooth muscle cell proliferation by modulating the E2F-1/Rb pathway. Am J Physiol Lung Cell Mol Physiol. 2003;284:L1063–L1071.
   PubMed Web of Science ®Google Scholar
• Du CL, Xu YJ, Liu XS, Xie JG, Zhang ZX, Zhang J, Qiao LF: The role of cyclinD1 in regulating passively sensitized human airway smooth muscle cells proliferation. Chin J Intern Med. 2008,47:143–144.
   Google Scholar
• Black JL, Johnson PR: What determines asthma phenotype? Is it the interaction between allergy and the smooth muscle? Am J Respir Crit Care Med. 2000;161:S207–S210.
   PubMed Web of Science ®Google Scholar
• Johnson PR, Black JL, Carlin S, Ge Q, Underwood PA: The production of extracellular matrix proteins by human passively sensitized airway smooth-muscle cells in culture: the effect of beclomethasone. Am J Respir Crit Care Med. 2000;162:2145–2151.
   PubMed Web of Science ®Google Scholar
• Bai J, Liu XS, Xu YJ, Xie M: Regulation of cell proliferation and apoptosis by ERK signaling pathway in airway smooth muscle cells of rats. Chin J Biochem Mol Biol. 2007;23:38–44.
   Google Scholar
• Bokhari SM, Zhou L, Karasek MA, Paturi SG, Chaudhuri V: Regulation of skin microvasculature angiogenesis, cell migration, and permeability by a specific inhibitor of PKCalpha. J Invest Dermatol. 2006;126:460–467.
   PubMed Web of Science ®Google Scholar
• Bornancin F, Parker PJ: Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Calpha. Curr Biol. 1996;6:1114–1123.
   PubMed Web of Science ®Google Scholar
• Parekh DB, Ziegler W, Parker PJ: Multiple pathways control protein kinase C phosphorylation. EMBO J. 2000;19:496–503.
   PubMedGoogle Scholar
• Tan M, Li P, Sun M, Yin G, Yu D: Upregulation and activation of PKC alpha by ErbB2 through Src promotes breast cancer cell invasion that can be blocked by combined treatment with PKC alpha and Src inhibitors. Oncogene. 2006;25:3286–3295.
   PubMed Web of Science ®Google Scholar
• Soh JW, Weinstein IB: Roles of specific isoforms of protein kinase C in the transcriptional control of cyclin D1 and related genes. J Biol Chem. 2003;278:34709–34716.
   PubMedGoogle Scholar
• Ramakrishnan M., Musa NL, Li J, Liu PT, Pestell RG, Hershenson MB: Catalytic activation of extracellular signal-regulated kinases induces cyclin D1 expression in airway smooth muscle. Am. J. Respir Cell Mol. Biol. 1998;18:736–740.
   PubMed Web of Science ®Google Scholar
• Lee JH, Johnson PR, Roth M, Hunt NH, Black JL: ERK activation and mitogenesis in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2001;280:L1019–L1029.
   PubMed Web of Science ®Google Scholar
• Page K, Li J, Wang Y, Kartha S, Pestell RG, Hershenson MB: Regulation of cyclin D1 expression and DNA synthesis by phosphatidylinositol 3-kinase in airway smooth muscle cells. Am J Respir Cell Mol Biol. 2000;23:436–443.
   PubMed Web of Science ®Google Scholar
• Thomas CF Jr, Limper AH: Phosphatidylinositol kinase regulation of airway smooth muscle cell proliferation. Am J Respir Cell Mol Biol. 2000;23:429–430.
   PubMed Web of Science ®Google Scholar
• Kolch W, Heidecker G, Kochs G, Hummel R, Vahidi H, Mischak H, Finkenzeller G, Marmé D, Rapp UR: Protein kinase C alpha activates RAF-1 by direct phosphorylation. Nature. 1993;364:249–252.
   PubMed Web of Science ®Google Scholar
• Whelchel A, Evans J, Posada J: Inhibition of ERK activation attenuates endothelin-stimulated airway smooth muscle cell proliferation. Am J Respir Cell Mol Biol. 1997;16:589–596.
   Google Scholar
• Schonwasser DC, Marais RM, Marshall CJ, Parker PJ: Activation of the mitogen-activated protein kinase/extracellular signal-regulatedkinase pathway by conventional, novel, and atypical protein kinase C isotypes. Mol Cell Biol. 1998;18:790–798.
   PubMed Web of Science ®Google Scholar
• Buitrago CG, Pardo VG, de Boland AR, Boland R: Activation of RAF-1 through Ras and protein kinase Ca mediates 1α,25(OH)2-vitamin D3 regulation of the mitogen-activated protein kinase pathway in muscle cells. J Biol Chem. 2003;278:2199–2205.
   PubMed Web of Science ®Google Scholar
• Trushin SA, Pennington KN, Carmona EM, Asin S, Savoy DN, Billadeau DD, Paya CV: Protein kinase Calpha (PKCalpha) acts upstream of PKCtheta to activate IkappaB kinase and NF-kappaB in T lymphocytes. Mol Cell Biol. 2003;23:7068–7081.
   PubMedGoogle Scholar
• Xiong W, Pestell RG, Watanabe G, Li J, Rosner MR, Hershenson MB: Cyclin D1 is required for S phase traversal in bovine tracheal myocytes. Am J Physiol. 1997;272:L1205–L1210.
   PubMed Web of Science ®Google Scholar