Xuebijing protects against lipopolysaccharide-induced lung injury in rabbits

REFERENCES

• Perl M, Lomas-Neira J, Chung CS, Ayala A: Epithelial cell apoptosis and neutrophil recruitment in acute lung injury—a unifying hypothesis? What we have learned from small interfering RNAs. Mol Med. 2008;14:465–475.
   PubMed Web of Science ®Google Scholar
• Fenton MJ, Golenbock DT: LPS-binding proteins and receptors. J Leukoc Biol. 1998;64:25–32.
   PubMed Web of Science ®Google Scholar
• Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, Vega F, Yu N, Wang J, Singh K, Zonin F, Vaisberg E, Churakova T, Liu M, Gorman D, Wagner J, Zurawski S, Liu Y, Abrams JS, Moore KW, Rennick D, de Waal-Malefyt R, Hannum C, Bazan JF, Kastelein RA: Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity. 2002;13:715–725.
   Web of Science ®Google Scholar
• Cua DJ, Sherlock J, Chen Y, Murphy CA, Joyce B, Seymour B, Lucian L, To W, Kwan S, Churakova T, Zurawski S, Wiekowski M, Lira SA, Gorman D, Kastelein RA, Sedgwick JD: Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature. 2003;421:744–748.
   PubMed Web of Science ®Google Scholar
• Cooper AM, Kipnis A, Turner J, Magram J, Ferrante J, Orme IM: Mice lacking bioactive IL-12 can generate protective, antigenspecific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present. J Immunol. 2002;168:1322–1327.
   PubMed Web of Science ®Google Scholar
• Ai YH, Yao YM, Dai XG: Effect of apoptosis of CD4+ CD25+ regulatory T cells on proliferation as well as secretion of effector T cells and intraventional activity of Xuebijing injection in septic rats. Chin Crit Care Med. 2009;47:58–61.
   Google Scholar
• Wang Q, Yao YM, Wang WJ, Xian LM, Dong N, Xu S, Dou KF: Effect of xuebijing injection on renal high mobility group box-1 protein expression and acute kidney injury in rats after scald injury. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2007;29:478–483.
   PubMedGoogle Scholar
• Gu XY, Chen WY, Wang SZ, Zhang JZ, Lu FP, Liu L: Protective effects of Xuebijing inject on organ function in patients with MODS. Chin Acad J. 2009;11:28–30.
   Google Scholar
• Li YP, Qiao YJ, Wu ZX, Qian FF, Yao YM, Wu Y: Effect of Xuebijing on protein C and tumor necrosis factor-alpha mRNA in rats with sepsis. Wei Zhong Bing Ji Jiu Yi Xue. 2007;19:488–491.
   PubMedGoogle Scholar
• Zhang P, Cao SH, Cui KL: The influences of Xuebijing on the expression of human leukocyte antigen-DR on monocytes in patients with multiple organ dysfunction syndrome. Zhong guo Zhong Xi Yi Jie He Za Zhi. 2002;9:21–23.
   Google Scholar
• Garrett S, Fitzgerald MC, Sullivan KE: LPS and poly I:C induce chromatin modifications at a novel upstream region of the IL-23 p19 promoter. Inflammation. 2008:31:235–246.
   PubMed Web of Science ®Google Scholar
• Liu FL, Chen CH, Chu SJ, Chen JH, Lai JH, Sytwu HK, Chang DM: Interleukin (IL)-23 p19 expression induced by IL-1{beta} in human fibroblast-like synoviocytes with rheumatoid arthritis via active nuclear factor-{kappa}B and AP-1 dependent pathway. Rheumatology. 2007:46:1266–1273.
   PubMed Web of Science ®Google Scholar
• Utsugi M, Dobashi K, Ishizuka T, Kawata T, Hisada T, Shimizu Y, Ono A, Mori M: Rac1 negatively regulates lipopolysaccharide-induced IL-23 p19 expression in human macrophages and dendritic cells and NF-kappaB p65 trans activation plays a novel role. J Immunol. 2006;177:4550–4557.
   PubMed Web of Science ®Google Scholar
• Yang CS, Song CH, Lee JS, Jung SB, Oh JH, Park J, Kim HJ, Park JK, Paik TH, Jo EK: Intracellular network of phosphatidylinositol 3-kinase, mammalian target of the rapamycin/70 kDa ribosomal S6 kinase 1, and mitogen-activated protein kinases pathways for regulating mycobacteria induced IL-23 expression in human macrophages. Cell Microbiol. 2006;8:1158–1171.
   PubMed Web of Science ®Google Scholar
• Poltorak A, He X, Smirnova I, Liu MY, Van Huffel C, Du X, Birdwell D, Alejos E, Silva M, Galanos C, Freudenberg M, Ricciardi-Castagnoli P, Layton B, Beutler B: Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science. 1998;282:2085–2088.
   PubMed Web of Science ®Google Scholar
• Dennehy KM, Willment JA, Williams DL, Brown GD: Reciprocal regulation of IL-23 and IL-12 following co-activation of Dectin-1 and TLR signaling pathways. Eur J Immunol. 2009;39:1379–1386.
   PubMed Web of Science ®Google Scholar
• Pirhonen J, Matikainen S, Julkunen I: Regulation of virus-induced IL-12 and IL-23 expression in human macrophages. J Immunol. 2002;169:5673–5678.
   PubMed Web of Science ®Google Scholar
• Schuetze N, Schoeneberger S, Mueller U, Freudenberg MA, Alber G, Straubinger RK: IL-12 family members:Differential kinetics of their TLR4-mediated induction by Salmonella enteritidis and the impact of IL-10 in bone marrow-derived macrophages. Int Immunol. 2005;17:649–659.
   PubMed Web of Science ®Google Scholar
• Wu HS, Zhang L, Chen Y, Guo XJ, Wang L, Xu JB, Wang CY, Zhang JH: Effect of nitric oxide on toll-like receptor 2 and 4 gene expression in rats with acute lung injury complicated by acute hemorrhage necrotizing pancreatitis. Hepatobiliary Pancreat Dis Int. 2005;4:609–613.
   PubMedGoogle Scholar
• Lee E, Trepicchio WL, Oestreicher JL, Pittman D, Wang F, Chamian F, Dhodapkar M, Krueger JG: Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. J Exp Med. 2004;199:125–130.
   PubMed Web of Science ®Google Scholar
• Fuss IJ, Becker C, Yang Z, Groden C, Hornung RL, Heller F, Neurath MF, Strober W, Mannon PJ: Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody. Inflamm Bowel Dis. 2006;12:9–15.
   PubMed Web of Science ®Google Scholar
• Schmidt C, Giese T, Ludwig B, Mueller-Molaian I, Marth T, Zeuzem S, Meuer SC, Stallmach A: Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis. Inflamm Bowel Dis. 2005;11:16–23.
   PubMed Web of Science ®Google Scholar
• Kim HR, Cho ML, Kim KW, Juhn JY, Hwang SY, Yoon CH, Park SH, Lee SH, Kim HY: Up-regulation of IL-23p19 expression in rheumatoid arthritis synovial fibroblasts by IL-17 through PI3-kinase-, NF-kappaB- and p38 MAPK-dependent signalling pathways. Rheumatology (Oxford). 2007;46:57–64.
   PubMed Web of Science ®Google Scholar
• Szabo SJ, Sullivan B M, Peng SL, Glimcher LH: Molecular mechanisms regulating Th1 immune responses. Annu Rev Immunol. 2003;21:713–758.
   PubMed Web of Science ®Google Scholar
• Fossiez, F, Banchereau J, Murray R, Van Kooten C, Garrone P, Lebecque S: Interleukin-17. Int Rev Immunol. 1998;16:541–551.
   PubMedGoogle Scholar
• Abraham C, Cho J: Interleukin-23/Th17 pathways and inflammatory bowel disease. Inflamm Bowel Dis. 2009;15:1090–1100.
   PubMed Web of Science ®Google Scholar
• Parham C, Chirica M, Timans J, Vais berg E, Travis M, Cheung J, Planz S, Zhang R, Sing KP, Vega F, To W, Wanger J, O’Farrel AM, McClanahan T, Zurawski S, Hannum C, Gorman D, Rennick DM, Kastelein RA, de Waal Malefyt R, Moore KW: A receptor for the heterodimeric cytokine IL-23 is composed of IL-23R betal and a novel cytokine receptor subunit, IL-23R. J Immunol. 2002;168:5699–5708.
   PubMed Web of Science ®Google Scholar
• Trinchieri G: Proinflammatory and immunoregulatory functions of interleukin-12. Int Rev Immunol. 1998;16:365–396.
   PubMedGoogle Scholar
• Reimann J, Rudolphi A, Tscherning T, Claesson MH: Selective engraftment of memory CD4+ T cells with an unusual recirculation pattern and a diverse T cell receptor-V beta repertoire into Scid mice. Eur J Immunol. 1993;23:350–356.
   PubMed Web of Science ®Google Scholar
• Li YP, Qiao YJ, Wu ZX, Qian FF, Yao YM, Yu Y, Wu Y: Effects of Xuebijing injection on protein C and tumor necrosis factor-alpha mRNA in rats with sepsis. Zhongguo Wei Zhong. 2007;19:488–491.
   PubMedGoogle Scholar
• Li ZJ, Sun YY, Wu YL, Li YP, Zhang WX, Liu HS, Wang CT: Experimental study of protective effects of Xuebijing injection on stress-induced organ damage in rabbit. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2006;18:105–108.
   PubMedGoogle Scholar
• Wang WJ, Yao YM, Xian LM, Dong N, Meng HD, Xue L, Wang CT: Effects of Xuebijing injection on multiple organ dysfunction and mortality in rats with delayed resuscitation for scald injury. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2006;18:16–18.
   PubMedGoogle Scholar