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Research Article

Role of neurogenic substance P in overexpression of alveolar macrophages’ neurokinin 1 receptor in mice exposed to cigarette smoke

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Pages 243-254 | Received 01 Jul 2009, Accepted 08 Oct 2009, Published online: 28 Apr 2010

REFERENCES

  • Anto JM, Vermeire P, Vestbo J, Sunyer J: Epidemiology of chronic obstructive pulmonary disease. Eur Respir J. 2001;17:982–994.
  • Bardelli C, Gunella G, Varsaldi F, Balbo P, Del Boca E, Bernardone IS, Amoruso A, Brunelleschi S: Expression of functional NK1 receptors in human alveolar macrophages: superoxide anion production, cytokine release and involvement of NF-kappaB pathway. Br J Pharmacol. 2005;145:385–396.
  • Kazeros A, Harvey BG, Carolan BJ, Vanni H, Krause A, Crystal RG: Overexpression of apoptotic cell removal receptor MERTK in alveolar macrophages of cigarette smokers. Am J Respir Cell Mol Biol. 2008;39:747–757.
  • Xu J, Xu F, Wang R, Seagrave J, Lin Y, March TH: Cigarette smoke-induced hypercapnic emphysema in C3H mice is associated with increases of macrophage metalloelastase and substance P in the lungs. Exp Lung Res. 2007;33:197–215.
  • Springer J, Groneberg DA, Pregla R, Fischer A: Inflammatory cells as source of tachykinin-induced mucus secretion in chronic bronchitis. Regul Pept. 2005;124:195–201.
  • Ofulue AF, Ko M: Effects of depletion of neutrophils or macrophages on development of cigarette smoke-induced emphysema. Am J Physiol. 1999;277:L97–L105.
  • De Swert KO, Bracke KR, Demoor T, Brusselle GG, Joos GF: Role of the tachykinin NK1 receptor in a murine model of cigarette smoke-induced pulmonary inflammation. Respir Res. 2009;10:37–48.
  • Barnes PJ: Neurogenic inflammation in the airways. Respir Physiol. 2001;125:145–154.
  • O’Connor TM, O’Connell J, O’Brien DI, Goode T, Bredin CP, Shanahan F: The role of substance P in inflammatory disease. J Cell Physiol. 2004;201:167–180.
  • Xu J, Xu F, Barrett E: Metalloelastase in lungs and alveolar macrophages is modulated by extracellular substance P in mice. Am J Physiol Lung Cell Mol Physiol. 2008;295:L162–L170.
  • Churg A, Zhou S, Wang X, Wang R, Wright JL: The role of interleukin-1beta in murine cigarette smoke-induced emphysema and small airway remodeling. Am J Respir Cell Mol Biol. 2009;40:482–490.
  • Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD: Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science. 1997;277:2002–2004.
  • Gerard NP, Bao L, Xiao-Ping H, Gerard C: Molecular aspects of the tachykinin receptors. Regul Pept. 1993;43:21–35.
  • Lee LY, Shuei Lin Y, Gu Q, Chung E, Ho CY: Functional morphology and physiological properties of bronchopulmonary C-fiber afferents. Anat Rec A Discov Mol Cell Evol Biol. 2003;270:17–24.
  • Helke CJ, O’Donohue TL, Jacobowitz DM: Substance P as a baro- and chemoreceptor afferent neurotransmitter: immunocytochemical and neurochemical evidence in the rat. Peptides. 1980;1:1–9.
  • Joshi DD, Dang A, Yadav P, Qian J, Bandari PS, Chen K, Donnelly R, Castro T, Gascon P, Haider A, : Negative feedback on the effects of stem cell factor on hematopoiesis is partly mediated through neutral endopeptidase activity on substance P: a combined functional and proteomic study. Blood. 2001;98:2697–2706.
  • Droemann D, Goldmann T, Tiedje T, Zabel P, Dalhoff K, Schaaf B: Toll-like receptor 2 expression is decreased on alveolar macrophages in cigarette smokers and COPD patients. Respir Res. 2005;6:68–75.
  • Simeonidis S, Castagliuolo I, Pan A, Liu J, Wang CC, Mykoniatis A, Pasha A, Valenick L, Sougioultzis S, Zhao D, : Regulation of the NK-1 receptor gene expression in human macrophage cells via an NF-kappa B site on its promoter. Proc Natl Acad Sci U S A. 2003;100:2957–2962.
  • Moretto N, Facchinetti F, Southworth T, Civelli M, Singh D, Patacchini R: alpha, beta-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases. Am J Physiol. 2009;296:L839–L848.
  • Sun J, Ramnath RD, Zhi L, Tamizhselvi R, Bhatia M: Substance P enhances NF-kappaB transactivation and chemokine response in murine macrophages via ERK1/2 and p38 MAPK signaling pathways. Am J Physiol Cell Physiol. 2008;294:C1586– C1596.
  • Gerard NP, Garraway LA, Eddy RL Jr, Shows TB, Iijima H, Paquet JL, Gerard C: Human substance P receptor (NK-1): organization of the gene, chromosome localization, and functional expression of cDNA clones. Biochemistry. 1991;30:10640–10646.
  • Pennefather JN, Lecci A, Candenas ML, Patak E, Pinto FM, Maggi CA: Tachykinins and tachykinin receptors: a growing family. Life Sci. 2004;74:1445–1463.
  • Brunelleschi S, Vanni L, Ledda F, Giotti A, Maggi CA, Fantozzi R: Tachykinins activate guinea-pig alveolar macrophages: involvement of NK2 and NK1 receptors. Br J Pharmacol. 1990;100:417–420.
  • Brylla E, Aust G, Geyer M, Uckermann O, Loffler S, Spanel-Borowski K: Coexpression of preprotachykinin A and B transcripts in the bovine corpus luteum and evidence for functional neurokinin receptor activity in luteal endothelial cells and ovarian macrophages. Regul Pept. 2005;125:125–133.
  • Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Trafton J, Petersen-Zeitz KR, Koltzenburg M, Basbaum AI, Julius D: Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science. 2000;288:306–313.
  • Jancso G, Kiraly E, Jancso-Gabor A: Pharmacologically induced selective degeneration of chemosensitive primary sensory neurones. Nature. 1977;270:741–743.
  • Xu F, Zhuang J, Wang R, Seagrave JC, March TH: Blunted ventilatory response to hypoxia/hypercapnia in mice with cigarette smoke-induced emphysema. Respir Physiol Neurobiol. 2007;158:5–13.
  • Matsunaga K, Klein TW, Friedman H, Yamamoto Y: Epigallocatechin gallate, a potential immunomodulatory agent of tea components, diminishes cigarette smoke condensate-induced suppression of anti-Legionella pneumophila activity and cytokine responses of alveolar macrophages. Clin Diagn Lab Immunol. 2002;9:864–871.
  • Inoue M, Kobayashi M, Kozaki S, Zimmer A, Ueda H: Nociceptin/orphanin FQ-induced nociceptive responses through substance P release from peripheral nerve endings in mice. Proc Natl Acad Sci U S A. 1998;95:10949–10953.
  • Killeen ME, Englert JA, Stolz DB, Song M, Han Y, Delude RL, Kellum JA, Fink MP: The phase 2 enzyme inducers ethacrynic acid, dl-sulforaphane, and oltipraz inhibit lipopolysaccharide-induced high-mobility group box 1 secretion by RAW 264.7 cells. J Pharmacol Exp Ther. 2006;316:1070–1079.
  • Narayan S, Jaiswal AS, Kang D, Srivastava P, Das GM, Gairola CG: Cigarette smoke condensate-induced transformation of normal human breast epithelial cells in vitro. Oncogene. 2004;23:5880–5889.
  • Hickstein DD, Baker DM, Gollahon KA, Back AL: Identification of the promoter of the myelomonocytic leukocyte integrin CD11b. Proc Natl Acad Sci U S A. 1992;89:2105–2109.
  • Gallicchio M, Rosa AC, Benetti E, Collino M, Dianzani C, Fantozzi R: Substance P-induced cyclooxygenase-2 expression in human umbilical vein endothelial cells. Br J Pharmacol. 2006;147:681–689.
  • Lee BS, Kim YM, Kang HS, Kim HM, Pyun KH, Choi I: Octamer binding protein-1 is involved in inhibition of inducible nitric oxide synthase expression by exogenous nitric oxide in murine liver cells. J Biochem. 2001;129:77–86.
  • Bai TR, Zhou D, Weir T, Walker B, Hegele R, Hayashi S, McKay K, Bondy GP, Fong T: Substance P (NK1)- and neurokinin A (NK2)-receptor gene expression in inflammatory airway diseases. Am J Physiol. 1995;269:L309–L317.
  • Mapp CE, Miotto D, Braccioni F, Saetta M, Turato G, Maestrelli P, Krause JE, Karpitskiy V, Boyd N, Geppetti P, : The distribution of neurokinin-1 and neurokinin-2 receptors in human central airways. Am J Respir Crit Care Med. 2000;161:207–215.
  • Hodge G, Nairn J, Holmes M, Reynolds PN, Hodge S: Increased intracellular T helper 1 proinflammatory cytokine production in peripheral blood, bronchoalveolar lavage and intraepithelial T cells of COPD subjects. Clin Exp Immunol. 2007;150:22–29.
  • Basyigit I, Yildiz F, Ozkara SK, Boyaci H, Ilgazli A: Inhaled corticosteroid effects both eosinophilic and non-eosinophilic inflammation in asthmatic patients. Mediators Inflamm. 2004;13:285–291.
  • Hu CP, Feng JT, Tang YL, Zhu JQ, Lin MJ, Yu ME: LIF upregulates expression of NK-1R in NHBE cells. Mediators Inflamm. 2006;2006:1–8.
  • Papavlassopoulos M, Stamme C, Thon L, Adam D, Hillemann D, Seydel U, Schromm AB: MaxiK blockade selectively inhibits the lipopolysaccharide-induced I kappa B-alpha /NF-kappa B signaling pathway in macrophages. J Immunol. 2006;177:4086–4093.
  • Persson-Sjogren S, Lejon K, Holmberg D, Forsgren S: Expression of the NK-1 receptor on islet cells and invading immune cells in the non-obese diabetic mouse. J Autoimmun. 2005;24:269–279.
  • Kaltreider HB, Ichikawa S, Byrd PK, Ingram DA, Kishiyama JL, Sreedharan SP, Warnock ML, Beck JM, Goetzl EJ: Upregulation of neuropeptides and neuropeptide receptors in a murine model of immune inflammation in lung parenchyma. Am J Respir Cell Mol Biol. 1997;16:133–144.
  • Bost KL, Breeding SA, Pascual DW: Modulation of the mRNAs encoding substance P and its receptor in rat macrophages by LPS. Regional Immunol. 1992;4:105–112.
  • Marriott I, Bost KL: IL-4 and IFN-gamma up-regulate substance P receptor expression in murine peritoneal macrophages. J Immunol. 2000;165:182–191.
  • Liu LY, Bates ME, Jarjour NN, Busse WW, Bertics PJ, Kelly EA: Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha. J Immunol. 2007;179:4840–4848.

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