Caerulein-induced acute pancreatitis results in mild lung inflammation and altered respiratory mechanics

REFERENCES

• Toouli J, Brooke-Smith M, Bassi C, Carr-Locke D, Telford J, Freeny P, Imrie C, Tandon R: Guidelines for the management of acute pancreatitis. J Gastroenterol Hepatol. 2002;17(S1):S15–S30.
   PubMedGoogle Scholar
• Bhatia M, Wong FL, Cao Y, Lau HY, Huang J, Puneet P, Chevali L: Pathophysiology of acute pancreatitis. Pancreatology. 2005;5:132–144.
   PubMed Web of Science ®Google Scholar
• Muhs BE, Patel S, Yee H, Marcus S, Shamamian P: Increased matrix metalloproteinase expression and activation following experimental acute pancreatitis. J Surg Res. 2001;101:21–28.
   PubMed Web of Science ®Google Scholar
• O'Brien G, Shields CJ, Winter DC, Dillon JP, Kirwan WO, Redmond HP: Cyclooxygenase-2 plays a central role in the genesis of pancreatitis and associated lung injury. Hepatobiliary Pancreat Dis Int. 2005;4;1:126–129.
   PubMedGoogle Scholar
• Severgnini M, Takahashi S, Tu P, Perides G, Homer RJ, Jhung JW, Bhavsar D, Cochran BH, Simon AR: Inhibition of the Src and Jak kinases protects against lipopolysaccharide-induced acute lung injury. Am J Respir Crit Care Med. 2005;171:858–867.
   PubMed Web of Science ®Google Scholar
• Nathens AB, Bitar R, Davreux C, Bujard M, Marshall JC, Dackiw APB, Watson RWG, Rotstein OD: Pyrrolidine dithiocarbamate attenuates endotoxin-induced acute lung injury. Am J Respir Cell Mol Biol. 1997;17:608–616.
   PubMed Web of Science ®Google Scholar
• Inoue S, Nakao A, Kishimoto W, Murakami H, Itoh K, Itoh T, Harada A, Nonami T, Takagi H: Anti-neutrophil antibody attenuates the severity of acute lung injury in rats with experimental acute pancreatitis. Arch Surg. 1995;130:93–98.
   PubMed Web of Science ®Google Scholar
• Bhatia M, Brady M, Zagorski J, Christmas SE, Campbell F, Neoptolemos JP, Slavin J: Treatment with neutralising antibody against cytokine induced neutrophil chemoattractant (CINC) protects rats against acute pancreatitis associated lung injury. Gut. 2000;47:838–844.
   PubMed Web of Science ®Google Scholar
• Ware LB, Matthay MA: The acute respiratory distress syndrome. N Engl J Med. 2000;342:1334–1349.
   PubMed Web of Science ®Google Scholar
• Bhatia M, Moochhala S: Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome. J Pathol. 2004;202:145–156.
   PubMed Web of Science ®Google Scholar
• Chaib E, Saldiva PH, Criado PM, Sakae RS, Machado MC: Evaluation of pulmonary elastance and resistance in acute pancreatitis. Experimental study in rats. Rev Hosp Clin Fac Med Sao Paulo. 1993;48:289–292.
   PubMedGoogle Scholar
• Lichtenstein A, Milani R, Fernezlian SM, Leme AS, Capelozzi VL, Martins MA: Acute lung injury in two experimental models of acute pancreatitis: infusion of saline or sodium taurocholate into the pancreatic duct. Crit Care Med. 2000;28:1497–1502.
   PubMed Web of Science ®Google Scholar
• Milani R, Pereira PM, Dolhnikoff M, Saldiva PH, Martins MA: Respiratory mechanics and lung morphometry in severe pancreatitis-associated acute lung injury in rats. Crit Care Med. 1995;23:1882–1889.
   PubMed Web of Science ®Google Scholar
• Berry AR, Taylor TV: Effect of drugs on the pulmonary changes in experimental acute pancreatitis in the rat. Gut. 1982;23:481–484.
   PubMed Web of Science ®Google Scholar
• Pirisi M, Scott CA, Fabris C, Cavarape A, Federico E, Falleti E, Beltrami CA: Endotoxin priming and liver damage by experimental duodenal obstruction in the rat. Pathol Int. 2000;50:34–40.
   PubMed Web of Science ®Google Scholar
• Bilchik AJ, Leach SD, Zucker KA, Modlin IM: Experimental models of acute pancreatitis. J Surg Res. 1990;48:639–647.
   PubMed Web of Science ®Google Scholar
• Sharma A, Tao X, Gopal A, Ligon B, Andrade-Gordon P, Steer ML, Perides G: Protection against acute pancreatitis by activation of protease-activated receptor-2. Am J Physiol Gastrointest Liver Physiol. 2004;288:388–395.
   Google Scholar
• Yamagiwa T, Shimosegawa T, Satoh A, Kimura K, Sakai Y, Masamune A: Inosine Alleviates rat caerulein pancreatitis and pancreatitis-associated lung injury. J Gastroenterol. 2004;39:41–49.
   PubMed Web of Science ®Google Scholar
• Elder ASF, Saccone GTP, Bersten AD, Dixon DL: l-Arginine-induced acute pancreatitis results in mild lung inflammation without altered respiratory mechanics. Exp Lung Res. 2010. Online ahead of print doi 10.3109/01902148.2010.495822
   Web of Science ®Google Scholar
• Davidson KG, Bersten AD, Barr HA, Dowling KD, Nicholas TE, Doyle IR: Endotoxin induces respiratory failure and increases surfactant turnover and respiration independent of alveolocapillary injury in rats. Am J Respir Crit Care Med. 2002;165:1516–1525.
   PubMed Web of Science ®Google Scholar
• Rifai Y, Elder ASF, Carati CJ, Hussey DJ, Li X, Woods CM, Schloithe AC, Thomas AC, Mathison RD, Davison JS, Toouli J, Saccone GTP: The tripeptide analog feG ameliorates severity of acute pancreatitis in a caerulein mouse model. Am J Physiol Gastrointest Liver Physiol. 2008;294: G1094–G1099.
   PubMed Web of Science ®Google Scholar
• Shields CJ, Winter DC, Sookhai S, Ryan L, Kirwan WO, Redmond HP: Hypertonic saline attenuates end-organ damage in an experimental model of acute pancreatitis. Br J Surg. 2000;87:1336–1340.
   PubMed Web of Science ®Google Scholar
• Dixon D-L, De Smet HR, Bersten AD: Lung mechanics are both dose and tidal volume dependant in LPS-induced lung injury. Respir Physiol Neurobiol. 2009;167:333–340.
   PubMed Web of Science ®Google Scholar
• Davidson KG, Bersten AD, Barr HA, Dowling KD, Nicholas TE, Doyle IR: Lung function, permeability, and surfactant composition in oleic acid-induced acute lung injury in rats. Am J Physiol Lung Cell Mol Physiol. 2000;297:L1091–L1102.
   Google Scholar
• Dixon DL, De Pasquale CG, De Smet HR, Klebe S, Orgeig S, Bersten AD: Reduced surface tension normalizes static lung mechanics in a rodent chronic heart failure model. Am J Respir Crit Care Med. 2009;180:181–187.
   PubMed Web of Science ®Google Scholar
• Sakai H, Ingenito EP, Mora R, Abbay S, Cavalcante FS, Lutchen KR, Suki B: Hysteresivity of the lung and tissue strip in the normal rat: effects of heterogeneities. J Appl Physiol. 2001;91:737–747.
   PubMed Web of Science ®Google Scholar
• Sly PD, Collins RA, Thamrin C, Turner DJ, Hantos Z: Volume dependence of airway and tissue impedances in mice. J Appl Physiol. 2003;94:1460–1466.
   PubMed Web of Science ®Google Scholar
• O'Donovan DA, Kelly CJ, Abdih H, Bouchier-Hayes D, Watson RWG, Redmond HP, Burke PE, Bouchier-Hayes DA: Role of nitric oxide in lung injury associated with experimental acute pancreatitis. Br J Surg. 1995;82:1122–1126.
   PubMed Web of Science ®Google Scholar
• Bellows CF, Brain JD: Role of Fibronectin in pancreatitis-associated lung injury. Digest Dis Sci. 2003;48:1445–1452.
   PubMed Web of Science ®Google Scholar
• Norkina O, Graf R, Appenzeller P, De Lisle RC: Caerulein-induced acute pancreatitis in mice that constitutively overexpress Reg/PAP genes. BMC Gastroenterol. 2006;6: 1–11.
   PubMedGoogle Scholar
• Esrefoglu M, Gul M, Ates B, Batcioglu K, Selimoglu MA: Antioxidative effect of melatonin, ascorbic acid and N-acetylcysteine on caerulein-induced pancreatitis and associated liver injury in rats. World J Gastroenterol. 2006;12:259–264.
   PubMed Web of Science ®Google Scholar
• Bhatia M, Wong FL, Fu D, Lau HY, Moochhala SM, Moore PK: Role of hydrogen sulfide in acute pancreatitis and associated lung injury. FASEB J. 2005;19:623–625.
   PubMed Web of Science ®Google Scholar
• Yan Q, Yao X, Dai LC, Zhang GL, Ping JL, He JF, Han CF: Effect of early administration of exogenous basic fibroblast growth factor on acute edematous pancreatitis in rats. World J Gastroenterol. 2006;12:3060–3064.
   PubMed Web of Science ®Google Scholar
• Gomez-Cambronero L, Camps B, de La Asuncion JG, Cerda M, Pellin A, Pallardo FV, Calvete J, Sweiry JH, Mann GE, Vina J, Sastre J: Pentoxifylline ameliorates cerulein-induced pancreatitis in rats: role of glutathione and nitric oxide. J Pharmacol Exp Ther. 2000;293:670–676.
   PubMed Web of Science ®Google Scholar
• Jo YJ, Choi HS, Jun DW, Lee OY, Kang JS, Park G, Jung KH, Hahm JS: The effects of a new human leukocyte elastase inhibitor (recombinant guamerin) on cerulein-induced pancreatitis in rats. Int Immunopharmacol. 2008;8:959–966.
   PubMed Web of Science ®Google Scholar
• Sugita H, Yamaguchi Y, Ikei S, Ogawa M: Effects of propentofylline on tumor necrosis factor-alpha and cytokine-induced neutrophil chemoattractant production in rats with cerulein-induced pancreatitis and endotoxemia. Pancreas. 1997;14:267–275.
   PubMed Web of Science ®Google Scholar
• Ishibashi T, Zhao H, Kawabe K, Oono T, Egashira K, suzuki K, Nawata H, Takayanagi R, Ito T: Blocking of monocyte chemoattractant protein-1 (MCP-1) activity attenuates the severity of acute pancreatitis in rats. J Gastroenterol. 2008;43: 79–85.
   PubMed Web of Science ®Google Scholar
• Gomez JA, Molero X, Vaquero E, Alonso A, Salas A, Malagelada JR: Vitamin E attenuates biochemical and morphological features associated with development of chronic pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2004;287:G162–G169.
   PubMed Web of Science ®Google Scholar
• Fremont RD, Kallet RH, Matthay MA, Ware LB: Postobstructive pulmonary edema: a case for hydrostatic mechanisms. Chest. 2007;131:1742–1746.
   PubMed Web of Science ®Google Scholar
• Su X, Lee JW, Matthay ZA, Mednick G, Uchida T, Fang X, Gupta N, Matthay MA: Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats. Am J Respir Cell Mol Biol. 2007;37:186–192.
   PubMed Web of Science ®Google Scholar