Chitosan aerosol inhalation alleviates lipopolysaccharide- induced pulmonary fibrosis in rats

REFERENCES

• Chakraborty S, Chopra P, Hak A, Dastidar SG, Ray A: Hepatocyte growth factor is an attractive target for the treatment of pulmonary fibrosis. Expert Opin Investig Drugs. 2013;22(4):499–515.
   PubMed Web of Science ®Google Scholar
• Thannickal VJ, Toews GB, White ES, Lynch Iii JP, Martinez FJ: Mechanisms of pulmonary fibrosis. Annu Rev Med. 2004;55:395–417.
   PubMed Web of Science ®Google Scholar
• Hauber H-P, Blaukovitsch M: Current and future treatment options in idiopathic pulmonary fibrosis. Inflammation & Allergy-Drug Targets. 2010;9(3):158–172.
   Google Scholar
• Fulmer J, Elson N, Von Gal E, McLees B, MeMets D, Weinberger S, Kelman J, Crystal R: Treatment of idiopathic pulmonary fibrosis. Clin Res. 1978;26:538A.
   Google Scholar
• Behr J, Maier K, Degenkolb B, Krombach F, Vogelmeier C: Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis: adjunctive therapy to maintenance immunosuppression. Am J Respir Crit Care Med. 1997;156(6):1897–901.
   PubMed Web of Science ®Google Scholar
• Azuma A: Pirfenidone: antifibrotic agent for idiopathic pulmonary fibrosis. Expert Rev Respir Med. 2010;4(3):301–310.
   PubMedGoogle Scholar
• Azuma A, Taguchi Y, Ogura T, Ebina M, Taniguchi H, Kondoh Y, Suga M, Takahashi H, Nakata K, Sato A: Exploratory analysis of a phase III trial of pirfenidone identifies a subpopulation of patients with idiopathic pulmonary fibrosis as benefiting from treatment. Respir Res. 2011;12:143.
   PubMed Web of Science ®Google Scholar
• Thabut G, Mal H, Castier Y, Groussard O, Brugière O, Marrash-Chahla R, Lesèche G, Fournier M: Survival benefit of lung transplantation for patients with idiopathic pulmonary fibrosis. J Thorac Cardiovasc Surg. 2003;126(2):469–475.
   PubMed Web of Science ®Google Scholar
• Qiao Y, Bai X-F, Du Y-G: Chitosan oligosaccharides protect mice from LPS challenge by attenuation of inflammation and oxidative stress. Int Immunopharmacol. 2011;11(1):121–127.
   PubMed Web of Science ®Google Scholar
• Wu H, Yao Z, Bai X, Du Y, Lin B: Anti-angiogenic activities of chitooligosaccharides. Carbohydr Polym. 2008;73(1):105–110.
   Web of Science ®Google Scholar
• Shen K-T, Chen M-H, Chan H-Y, Jeng J-H, Wang Y-J: Inhibitory effects of chitooligosaccharides on tumor growth and metastasis. Food Chem Toxicol. 2009;47(8):1864–1871.
   PubMed Web of Science ®Google Scholar
• No H, Park N, Lee S, Hwang H, Meyers S: Antibacterial activities of chitosans and chitosan oligomers with different molecular weights on spoilage bacteria isolated from tofu. J Food Sci. 2002;67(4):1511–1514.
   Web of Science ®Google Scholar
• Xu J, Zhao X, Han X, Du Y: Antifungal activity of oligochitosan against Phytophthora capsici and other plant pathogenic fungi in vitro. Pestic Biochem Physiol. 2007;87(3):220–228.
   Web of Science ®Google Scholar
• Muzzarelli RA: Chitins and chitosans for the repair of wounded skin, nerve, cartilage and bone. Carbohydr Polym. 2009;76(2):167–182.
   Web of Science ®Google Scholar
• Minagawa T, Okamura Y, Shigemasa Y, Minami S, Okamoto Y: Effects of molecular weight and deacetylation degree of chitin/chitosan on wound healing. Carbohydr Polym. 2007;67(4):640–644.
   Web of Science ®Google Scholar
• Park P-J, Je J-Y, Kim S-K: Free radical scavenging activity of chitooligosaccharides by electron spin resonance spectrometry. J Agric Food Chem. 2003;51(16):4624–4627.
   PubMed Web of Science ®Google Scholar
• Liu H-T, Li W-M, Xu G, Li X-Y, Bai X-F, Wei P, Yu C, Du Y-G: Chitosan oligosaccharides attenuate hydrogen peroxide-induced stress injury in human umbilical vein endothelial cells. Pharmacol Res. 2009;59(3):167–175.
   PubMed Web of Science ®Google Scholar
• Yoon HJ, Moon ME, Park HS, Im SY, Kim YH: Chitosan oligosaccharide (COS) inhibits LPS-induced inflammatory effects in RAW 264.7 macrophage cells. Biochem Biophys Res Commun. 2007;358(3):954–959.
   PubMed Web of Science ®Google Scholar
• Diegelmann RF, Dunn JD, Lindblad WJ, Cohen IK: Analysis of the effects of chitosan on inflammation, angiogenesis, fibroplasia, and collagen deposition in polyvinyl alcohol sponge implants in rat wounds. Wound Repair Regen. 1996;4(1):48–52.
   PubMedGoogle Scholar
• Ishihara M, Ono K, Sato M, Nakanishi K, Saito Y, Yura H, Matsui T, Hattori H, Fujita M, Kikuchi M: Acceleration of wound contraction and healing with a photocrosslinkable chitosan hydrogel. Wound Repair Regen. 2001;9(6):513–521.
   PubMed Web of Science ®Google Scholar
• Hamano T, Teramoto A, Iizuka E, Abe K: Effects of polyelectrolyte complex (PEC) on human periodontal ligament fibroblast (HPLF) function. II. Enhancement of HPLF differentiation and aggregation on PEC by L-ascorbic acid and dexamethasone. J Biomed Mater Res. 1998;41(2):270–277.
   PubMed Web of Science ®Google Scholar
• Chatelet C, Damour O, Domard A: Influence of the degree of acetylation on some biological properties of chitosan films. Biomaterials. 2001;22(3):261–268.
   PubMed Web of Science ®Google Scholar
• Okamoto Y, Shibazaki K, Minami S, Matsuhashi A, Tanioka S, Shigemasa Y: Evaluation of chitin and chitosan on open would healing in dogs. J Vet Med Sci. 1995;57(5):851–854.
   PubMed Web of Science ®Google Scholar
• Wang B-L, Tu Y-Y, Fu J-F, Zhong Y-X, Fu G-Q, Tian X-X, Wang L-H, Gong L, Ren Q-Y: Unbalanced MMP/TIMP-1 expression during the development of experimental pulmonary fibrosis with acute paraquat poisoning. Mol Med Rep. 2011;4(2):243–248.
   Web of Science ®Google Scholar
• Yamashita CM, Dolgonos L, Zemans RL, Young SK, Robertson J, Briones N, Suzuki T, Campbell MN, Gauldie J, Radisky DC: Matrix metalloproteinase 3 is a mediator of pulmonary fibrosis. Am J Pathol. 2011;179(4):1733–1745.
   PubMed Web of Science ®Google Scholar
• Institute of Laboratory Animal Resources (US). Guide for the Care and Used of Laboratory Animals. Washington, DC: National Academies Press; 1996.
   Google Scholar
• Mohammadi Z, Dorkoosh F, Hosseinkhani S, Gilani K, Amini T, Najafabadi AR, Tehrani MR: In vivo transfection study of chitosan-DNA-FAP-B nanoparticles as a new non viral vector for gene delivery to the lung. Int J Pharm. 2011;421(1):183–188.
   PubMed Web of Science ®Google Scholar
• Ashcroft T, Simpson JM, Timbrell V: Simple method of estimating severity of pulmonary fibrosis on a numerical scale. J Clin Pathol. 1988;41(4):467–470.
   PubMed Web of Science ®Google Scholar
• Page-McCaw A, Ewald AJ, Werb Z: Matrix metalloproteinases and the regulation of tissue remodelling. Nat Rev Mol Cell Biol. 2007;8(3):221–233.
   PubMed Web of Science ®Google Scholar
• Radisky DC, Levy DD, Littlepage LE, Liu H, Nelson CM, Fata JE, Leake D, Godden EL, Albertson DG, Nieto MA: Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability. Nature. 2005;436(7047):123–127.
   PubMed Web of Science ®Google Scholar
• Selman M, Pardo A, Kaminski N: Idiopathic pulmonary fibrosis: aberrant recapitulation of developmental programs? PLoS Med. 2008;5(3):373–380.
   Web of Science ®Google Scholar
• Handsley MM, Edwards DR: Metalloproteinases and their inhibitors in tumor angiogenesis. Int J Cancer. 2005;115(6):849–860.
   PubMed Web of Science ®Google Scholar
• Jumper C, Cobos E, Lox C: Determination of the serum matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in patients with either advanced small-cell lung cancer or non-small-cell lung cancer prior to treatment. Respi Med. 2004;98(2):173–177.
   PubMed Web of Science ®Google Scholar
• Ohbayashi H: Matrix metalloproteinases in lung diseases. Curr Protein Pept Sci. 2002;3(4):409–421.
   PubMed Web of Science ®Google Scholar
• de Jesus Valle M, Dinis-Oliveira R, Carvalho F, Bastos M, Navarro AS: Toxicological evaluation of lactose and chitosan delivered by inhalation. J Biomater Sci Polym Ed. 2008;19(3):387–397.
   PubMed Web of Science ®Google Scholar