Comparison of CT-derived ventilation maps with deposition patterns of inhaled microspheres in rats

REFERENCES

• Rostami AA: Computational modeling of aerosol deposition in respiratory tract: a review. Inhal Toxicol. [Review]. 2009;21(4):262–290.
   PubMed Web of Science ®Google Scholar
• Yin Y, Choi J, Hoffman EA, Tawhai MH, Lin CL: Simulation of pulmonary air flow with a subject-specific boundary condition. J Biomech. [Research Support, N.I.H., Extramural]. 2010;43(11):2159–2163.
   PubMed Web of Science ®Google Scholar
• Wall WA, Wiechert L, Comerford A, Rausch S: Towards a comprehensive computational model for the respiratory system. Int J Numer Meth Bio. 2010;26(7):807–827.
   Web of Science ®Google Scholar
• Corley RA, Kabilan S, Kuprat AP, Carson JP, Minard KR, Jacob RE, et al.: Comparative computational modeling of airflows and vapor dosimetry in the respiratory tracts of rat, monkey, and human. Toxicol Sci. [Comparative Study Research Support, N.I.H., Intramural]. 2012;128(2):500–516.
   PubMed Web of Science ®Google Scholar
• Asgharian B, Price O, McClellan G, Corley R, Einstein DR, Jacob RE, et al.: Development of a rhesus monkey lung geometry model and application to particle deposition in comparison to humans. Inhal Toxicol. [Comparative Study Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.]. 2012;24(13):869–899.
   PubMed Web of Science ®Google Scholar
• Schroeter JD, Asgharian B, Price OT, McClellan GE: Computational fluid dynamics simulations of inhaled nano- and microparticle deposition in the rhesus monkey nasal passages. Inhal Toxicol. [Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.]. 2013;25(12):691–701.
   PubMed Web of Science ®Google Scholar
• Schroeter JD, Garcia GJ, Kimbell JS: A computational fluid dynamics approach to assess interhuman variability in hydrogen sulfide nasal dosimetry. Inhal Toxicol. [Research Support, Non-U.S. Gov't]. 2010 Mar;22(4):277–286.
   PubMed Web of Science ®Google Scholar
• Castillo R, Castillo E, McCurdy M, Gomez DR, Block AM, Bergsma D, et al.: Spatial correspondence of 4D CT ventilation and SPECT pulmonary perfusion defects in patients with malignant airway stenosis. Phys Med Biol. [Research Support, N.I.H., Extramural]. 2012;57(7):1855–1871.
   PubMed Web of Science ®Google Scholar
• Fuld MK, Easley RB, Saba OI, Chon D, Reinhardt JM, Hoffman EA, et al.: CT-measured regional specific volume change reflects regional ventilation in supine sheep. J Appl Physiol. (1985). [Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.]. 2008;104(4):1177–1184.
   PubMed Web of Science ®Google Scholar
• Guerrero T, Castillo R, Sanders K, Price R, Komaki R, Cody D: Novel method to calculate pulmonary compliance images in rodents from computed tomography acquired at constant pressures. Phys Med Biol. [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]. 2006;51(5):1101–1112.
   PubMed Web of Science ®Google Scholar
• Mathew L, Wheatley A, Castillo R, Castillo E, Rodrigues G, Guerrero T, et al.: Hyperpolarized (3)He magnetic resonance imaging: comparison with four-dimensional x-ray computed tomography imaging in lung cancer. Acad Radiol. [Comparative Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]. 2012;19(12):1546–1553.
   PubMed Web of Science ®Google Scholar
• Ding K, Cao K, Fuld MK, Du K, Christensen GE, Hoffman EA, et al.: Comparison of image registration based measures of regional lung ventilation from dynamic spiral CT with Xe-CT. Med Phys. [Research Support, N.I.H., Extramural]. 2012;39(8):5084–5098.
   PubMed Web of Science ®Google Scholar
• Du K, Bayouth JE, Cao K, Christensen GE, Ding K, Reinhardt JM: Reproducibility of registration-based measures of lung tissue expansion. Med Phys. [Research Support, N.I.H., Extramural]. 2012;39(3):1595–1608.
   PubMed Web of Science ®Google Scholar
• Reinhardt JM, Ding K, Cao K, Christensen GE, Hoffman EA, Bodas SV: Registration-based estimates of local lung tissue expansion compared to xenon CT measures of specific ventilation. Med Image Anal. [Comparative Study Research Support, N.I.H., Extramural]. 2008;12(6):752–763.
   PubMed Web of Science ®Google Scholar
• Yamamoto T, Kabus S, Lorenz C, Johnston E, Maxim PG, Diehn M, et al.: 4D CT lung ventilation images are affected by the 4D CT sorting method. Med Phys. [Research Support, N.I.H., Extramural]. 2013;40(10):101907.
   PubMed Web of Science ®Google Scholar
• Yin Y: MDCT-Based Dynamic, Subject-Specific Lung Models via Image Registraion for CFD-based Interrogation of Regional Lung Function. Iowa City, IA: University of Iowa; 2011.
   Google Scholar
• Jacob RE, Carson JP, Thomas M, Einstein DR: Dynamic multiscale boundary conditions for 4D CT of healthy and emphysematous rats. PloS One. 2013;8(6):e65874.
   PubMed Web of Science ®Google Scholar
• Kipritidis J, Siva S, Hofman MS, Callahan J, Hicks RJ, Keall PJ: Validating and improving CT ventilation imaging by correlating with ventilation 4D-PET/CT using 68Ga-labeled nanoparticles. Med Phys. [Research Support, Non-U.S. Gov't]. 2014;41(1):011910.
   Web of Science ®Google Scholar
• Castillo R, Castillo E, Martinez J, Guerrero T: Ventilation from four-dimensional computed tomography: density versus Jacobian methods. Phys Med Biol. [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]. 2010;55(16):4661–4685.
   PubMed Web of Science ®Google Scholar
• Minard KR, Kuprat AP, Kabilan S, Jacob RE, Einstein DR, Carson JP, et al.: Phase-contrast MRI and CFD modeling of apparent (3)He gas flow in rat pulmonary airways. J Magn Reson. [Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.]. 2012;221:129–138.
   PubMed Web of Science ®Google Scholar
• Yang W, Peters JI, Williams RO, 3rd: Inhaled nanoparticles—a current review. Int J Pharm. [Review]. 2008;356(1–2):239–247.
   PubMed Web of Science ®Google Scholar
• Jacob RE, Carson JP: Automated measurement of heterogeneity in CT images of healthy and diseased rat lungs using variogram analysis of an octree decomposition. BMC Med Imag. 2014;14(1):1.
   PubMed Web of Science ®Google Scholar
• Jacob RE, Lamm WJ: Stable small animal ventilation for dynamic lung imaging to support computational fluid dynamics models. PloS One. 2011;6(11):e27577.
   PubMed Web of Science ®Google Scholar
• Jacob RE, Murphy MK, Creim JA, Carson JP: Detecting radiation-induced injury using rapid 3D variogram analysis of CT images of rat lungs. Acad Radiol. 2013;20(10):1264–1271.
   PubMed Web of Science ®Google Scholar
• Robertson HT, Krueger MA, Lamm WJ, Glenny RW: High-resolution spatial measurements of ventilation-perfusion heterogeneity in rats. J Appl Physiol (1985). [Research Support, N.I.H., Extramural Validation Studies]. 2010;108(5): 1395–1401.
   PubMed Web of Science ®Google Scholar
• Henning A, Schneider M, Nafee N, Muijs L, Rytting E, Wang X, et al.: Influence of particle size and material properties on mucociliary clearance from the airways. J Aerosol Med Pulm Drug Deliv. [Research Support, Non-U.S. Gov't Review]. 2010;23(4):233–241.
   PubMed Web of Science ®Google Scholar
• Bernard SL, Ewen JR, Barlow CH, Kelly JJ, McKinney S, Frazer DA, et al.: High spatial resolution measurements of organ blood flow in small laboratory animals. Am J Physiol Heart Circ Physiol. [Validation Studies]. 2000;279(5):H2043–H2052.
   PubMed Web of Science ®Google Scholar
• Glenny RW, Bauer C, Hofmanninger J, Lamm WJ, Krueger MA, Beichel RR: Heterogeneity and matching of ventilation and perfusion within anatomical lung units in rats. Respir Physiol Neurobiol. [Research Support, N.I.H., Extramural]. 2013;189(3):594–606.
   PubMed Web of Science ®Google Scholar
• Tustison NJ, Avants BB: Explicit B-spline regularization in diffeomorphic image registration. Front Neuroinform. 2013;7(39).
   Google Scholar
• Avants BB, Epstein CL, Grossman M, Gee JC: Symmetric diffeomorphic image registration with cross-correlation: evaluating automated labeling of elderly and neurodegenerative brain. Med Image Anal. 2008;12(1):26–41.
   PubMed Web of Science ®Google Scholar
• Avants BB, Tustison NJ, Song G, Cook PA, Klein A, Gee JC: A reproducible evaluation of ANTs similarity metric performance in brain image registration. NeuroImage. 2011;54(3):2033–2044.
   PubMed Web of Science ®Google Scholar
• Zhang R, Zhou W, Li Y, Yu S, Xie Y: Nonrigid registration of lung CT images based on tissue features. Comp Math Methods Med. [Research Support, Non-U.S. Gov't]. 2013;2013: 834192.
   PubMedGoogle Scholar
• Wright JL, Cosio M, Churg A: Animal models of chronic obstructive pulmonary disease. Am J Physiol Lung Cell Mol Physiol. [Research Support, Non-U.S. Gov't Review]. 2008;295(1):L1–L15.
   PubMed Web of Science ®Google Scholar
• Kadlecek SJ, Emami K, Fischer MC, Ishii M, Yu JS, Woodburn JM, et al.: Imaging physiological parameters with hyperpolarized gas MRI. Prog Nucl Mag Res Sp. 2005;47(3–4):187–212.
   Web of Science ®Google Scholar
• Swift AJ, Wild JM, Fichele S, Woodhouse N, Fleming S, Waterhouse J, et al.: Emphysematous changes and normal variation in smokers and COPD patients using diffusion 3He MRI. Eur J Radiol. 2005;54(3):352–358.
   PubMed Web of Science ®Google Scholar
• Kyriazis A, Rodriguez I, Nin N, Izquierdo-Garcia JL, Lorente JA, Perez-Sanchez JM, et al.: Dynamic ventilation 3He MRI for the quantification of disease in the rat lung. IEEE Trans Biomed Eng. [Research Support, Non-U.S. Gov't]. 2012;59(3):777–786.
   PubMed Web of Science ®Google Scholar
• Sweeney TD, Brain JD, Leavitt SA, Godleski JJ: Emphysema alters the deposition pattern of inhaled particles in hamsters. Am J Pathol. [Research Support, U.S. Gov't, P.H.S.]. 1987;128(1):19–28.
   PubMed Web of Science ®Google Scholar
• Oakes JM, Breen EC, Scadeng M, Tchantchou GS, Darquenne C: Mri-based measurements of aerosol deposition in the lung of healthy and elastase-treated rats. J Appl Physiol. (1985);2014. doi:10.1152/japplphysiol.01165.2013.
   Web of Science ®Google Scholar
• Geiser M, Schurch S, Gehr P: Influence of surface chemistry and topography of particles on their immersion into the lung's surface-lining layer. J Appl Physiol. (1985). [Research Support, Non-U.S. Gov't]. 2003;94(5):1793–1801.
   Web of Science ®Google Scholar
• Tsuda A, Rogers RA, Hydon PE, Butler JP: Chaotic mixing deep in the lung. Proc Natl Acad Sci U S A. [In Vitro Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.]. 2002;99(15):10173–10178.
   PubMed Web of Science ®Google Scholar