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Original Article

Lymphokine-Induced Phenotypic Changes in Cells of a Type 2 Pneumocyte-Related Strain: Characterization of Activity in Mitogen-Stimulated Spleen Cell Supernatants

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Pages 127-140 | Received 19 May 1986, Accepted 09 Nov 1986, Published online: 02 Jul 2009

References

  • Evans M J, Cabral L J, Stephens R J, Freeman G. Renewal of alveolar epithelium in the rat following exposure to NO2. Am J Pathol 1973; 70: 175–198
  • Adamson I YR, Bowden D H. The Type II cell as progenitor of alveolar epithelial regeneration: A cytodynamic study in mice after exposure to oxygen. Lab Invest 1974; 30: 35–42
  • Chretien J, Basset F, Jaubert F, Soler P, Danel C. Cellular biology and pathology of Type II pneumocytes. Int Archs Allergy Appl Immunol 1985; 76(Supp 1)49–61
  • Wahl S M, Wahl L M. Modulation of fibroblast growth and function by monokines and lymphokines. Lymphokines 1981; 2: 179–201
  • Hunninghake G W, Garrett K C, Richerson H B, Fantone J C, Ward P A, Rennard S I, Bitterman P B, Crystal R G. Pathogenesis of the granulomatous lung diseases. Am Rev Resp Dis 1984; 130: 476–496
  • Kumar R K, Truscott J Y, Hristoforidis C P, Smith G J, Lykke A WJ. Altered morphology, growth and biosynthetic activity of a Type II pneumocyte-related cell strain induced by lymphokine-enriched supernatants of mitogen-stimulated spleen cells. Exp Lung Res 1986; 11: 129–144
  • Smith G J, Le Mesurier S M, de Montfort M L, Lykke A WJ. Establishment of epithelial cell strains from normal adult mouse lung resembling a urethane-induced lung adenoma cell strain and a metastasizing mouse lung carcinoma cell line. Cell Biol Internat Rep 1984; 8: 161–169
  • Smith G J, Le Mesurier S M, de Montfort M L, Lykke A WJ. Development and characterization of Type II pneumocyte-related cell lines from normal adult mouse lung. Pathology 1984; 16: 401–405
  • Chen T R. In situ detection of mycoplasma contamination of cell cultures by fluorescent Hoescht 33258. Exp Cell Res 1977; 104: 255–262
  • Smith G J, Kumar R K, Hristoforidis C P, Lykke A WJ. Expression of a Type II pneumocyte-specific antigen by a cell strain from normal adult mouse lung. Cell Biol Internat Rep 1985; 9: 1115–1122
  • Friedrich W, Lazary S, Geczy C L, de Weck A L. Lymphokines. I. Use of insoluble concanavalin A for the production of migration inhibitory factor in guinea pig lymphocyte cultures. Int Arch Allergy Appl Immunol 1975; 49: 504–518
  • Kumar R K. Separation and characterization of lymphocytes from rat lung parenchyma. Exp Lung Res 1984; 7: 113–122
  • Yam L T, Li C Y, Crosby W H. Cytochemical identification of monocytes and granulocytes. Am J Clin Pathol 1971; 55: 283–290
  • Rosenberg S A, Grimm E A, McGrogan M, Doyle M, Kawasaki E, Koths K, Mark D F. Biological activity of recombinant interleukin-2 produced in Escherichia coli. Science 1984; 223: 1412–1415
  • Gillis S, Mochizuki D Y, Conlon P J, Hefeneider S H, Ramthuin C A, Gillis A E, Frank M B, Henney C S, Watson J D. Molecular characterization of interleukin 2. Immunol Rev 1982; 63: 167–209
  • Paetkau V, Bleackley R C, Riendau D, Harnish D G, Holowachuk E W. Toward the molecular biology of IL-2. Contemp Top Mol Immunol 1985; 10: 35–61
  • Brouty-Boye D. Inhibitory effects of interferons on cell multiplication. Lymphokine Rep 1980; 1: 99–1111
  • Trinchieri G, Perussia B. Immune interferon: A pleiotropic lymphokine with multiple effects. Immunol Today 1985; 6: 131–136
  • Wietzerbin J, Stefanos S, Falcoff R, Lucero M, Catinot L, Falcoff E. Immune interferon induced by phytohemagglutinin in nude mouse spleen cells. Infect Immun 1978; 111: 966–9711
  • Youngner J S, Salvin S B. Production and properties of migration inhibitory factor and interferon in the circulation of mice with delayed hypersensitivity. J Immunol 1973; 111: 1914–1922
  • Wietzerbin J, Stefanos S, Lucero M, Falcoff E, O'Malley J A, Sulkowski E. Physico-chemical characterization and partial purification of mouse immune interferon. J Gen Virol 1979; 44: 773–781
  • Robb R J. Interleukin 2: The molecule and its function. Immunol Today 1984; 5: 203–209
  • Cohen M C, Mecley M, Antonia S J, Picciano P T. Adherence of tumor cells to endothelial monolayers: Inhibition by lymphokines. Cell Immunol 1985; 95: 247–257
  • Malek T R, Robb R J, Shevach E M. Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex. Proc Natl Acad Sci USA 1983; 80: 5694–5698
  • Pinkston P, Bitterman P B, Crystal R G. Spontaneous release of interleukin-2 by lung T-lymphocytes in active pulmonary sarcoidosis. N Engl J Med 1983; 308: 793–800
  • Robinson B WS, McLemore T L, Crystal R G. Gamma interferon is spontaneously produced by lung T-lymphocytes and alveolar macrophages in patients with pulmonary sarcoidosis. J Clin Invest 1985; 75: 1488–1495
  • Leslie C C, McCormick-Shannon K, Cook J L, Mason R J. Macrophages stimulate DNA synthesis in rat alveolar Type II cells. Am Rev Resp Dis 1985; 132: 1246–1252
  • Kovacs E J, Kelley J. Lymphokine regulation of macrophage derived growth factor secretion following pulmonary injury. Am J Pathol 1985; 121: 261–268

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