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Original Article

Physical Properties of Purified Human Respiratory Mucus Glycoproteins: Effects of Sodium Chloride Concentration on the Aggregation Properties and Shape

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Pages 721-737 | Received 15 Nov 1986, Accepted 15 Mar 1989, Published online: 02 Jul 2009

References

  • Allen A, Cunliffe W J, Pearson J P, Sellers L A, Ward R. Studies on gastrointestinal mucus. Scand J Gastroenterol 19 Supp 1984; 93: 101–113
  • Sturgess J M. Mucous secretions in the respiratory tract. Pediatr Clin North Am 1979; 26: 481–501
  • Gurwitz D, Corey M, Francis P WJ, Crozier D, Levison H. Perspectives, in cystic fibrosis. Pediatr Clin North Am 1979; 26: 603–615
  • Yeager H. Tracheobronchial secretions. Am J Med 1971; 50: 493–509
  • Litt M, Khan M A, Chakrin L W, Wardell J R, Christian P. The viscoelasticity of fractionated canine tracheal mucus. Biorheology 1974; 11: 111–117
  • Chen T M, Dulfano M J. Mucus viscoelasticity and mucociliary transport rate. J Lab Clin Med, 91: 423–431
  • Gelman R A, Meyer F A. Mucociliary transference rate and mucus viscoelasticity. Dependence on dynamic storage and loss modules. Am Rev Respir Dis 1979; 120: 53–557
  • Giordano A M, Holsclaw D, Litt M. Mucus rheology and mucociliary clearance: normal physiological state. Am Rev Respir Dis 1978; 118: 245–250
  • Dearborn D G. Water and electrolytes of exocrine secretions, J A Mangus, R C Talamo. Intercontinental Medical Book, Cystic Fibrosis, New York 1976; 179–191, Projections into the Future
  • Izutsu K, Johnson D, Schubert M, Wang E, Ramsey B, Tamarin A, Truelov E, Ensign W, Young M. Electron microprobe analysis of human labial gland secretory granules in cystic fibrosis. J Clin Invest 1985; 75: 1951–1956
  • Sachdev G P, Fox O F, Wen G, Schroeder T, Elkins R C, Carubelli R. Isolation and characterization of glycoproteins from canine tracheal mucus. Biochim Biophys Acta 1978; 536: 184–196
  • Sachdev G P, Zodrow J M, Carubelli R. Hydrophobic interaction of fluorescent probes with fetuin, ovine submaxillary mucin, and canine tracheal mucins. Biochim Biophys Acta 1979; 580: 85–90
  • Sachdev G P, Meyers F J, Horton F O, Wen G, Rogers R M, Carubelli R. Isolation chemical composition, and properties of the major mucin component of normal human tracheobronchial secretions. Biochem Med 1980; 24: 82–94
  • Chace K V, Leahy D S, Martin R, Carubelli R, Flux M, Sachdev G P. Respiratory mucous secretions in patients with cystic fibrosis: relationship between levels of highly sulfated mucin component and severity of the disease. Clin Chim Acta 1983; 132: 143–155
  • Chace K V, Flux M, Sachdev G P. Comparison of physicochemical properties of purified mucus glycoproteins isolated from respiratory secretions of cystic fibrosis and asthmatic patients. Biochemistry 1985; 24: 7334–7341
  • Khan M A, Wolf D P, Litt M. Effect of mucolytic agents on the rheological properties of tracheal mucus. Biochim Biophys Acta 1976; 444: 369–376
  • Brown D T, Marriott C, Beeson M F, Barrett-Bee K. Isolation and partial characterization of rheologically active fraction from pooled human sputum. Am Rev Respir Dis 1981; 124: 285–291
  • Holden K G, Yim N CF, Griggs L J, Weisbach J D. Gel electrophoresis of mucous glycoproteins I. Effect of gel porosity. Biochemistry 1971; 10: 3105–3109
  • Segrest J P, Jackson R L. Molecular weight determination of glycoproteins by polyacrylamide gel electrophoresis in sodium dodecyl sulfate. Methods Enzymol 1972; 28: 54–63
  • Slomiany A, Slomiany B L, Witas H, Aono M, Newman L J. Isolation of fatty acids covalently bound to the gastric mucus glycoprotein of normal and cystic fibrosis patients. Biochem Biophys Res Commun 1983; 113: 286–293
  • Wang C S, Weiser D, Alaupovic P, Mc Conathy W J. Studies on the degradation of human very low density lipoproteins by human milk lipase. Arch Biochem Biophys 1982; 214: 26–34
  • Kuksis A, Myher J J, Marai L, Geher K. Determination of plasma rapid profiles by automated gas chromatography and computerized data anlysis. J Chromatogr Sci 1975; 18: 423–430
  • Mc Conathy W J, Blackett P R, Kling O R. Studies on serum apolipoproteins and lipids in amniotic fluid and neonatal urine. Clin Chim Acta 1981; 111: 153–162
  • Carubelli R, Ryan R C, Trucco R E, Caputto R. Neuramin-lactose sulfate, a new compound isolated from the mammary gland of rats. J. Biol Chem 1961; 236: 2381–2388
  • Svennerholm L. Quantitative estimation of sialic acids II. A colorimetric resorcinol hydrochloric acid method. Biochim Biophys Acta 1975; 24: 604–611
  • Wang C S, Burns R K, Alaupovic P. Isolation and composition of oligosaccharide cores from endotoxins of two Serratia marcescens strains. J. Bacteriol 1974; 120: 990–993
  • Thomas P S, Farquhar M N. Specific measurement of DNA in nuclei and nucleic acids using diaminobenzoic acid. Anal Biochem 1978; 89: 35–44
  • Terho T T, Hartiala K. Method for determination of the sulfate content of glyco-saminoglycans. Anal Biochem 1971; 41: 471–476
  • Spackman D H. Accelerated methods. Methods Enzymol 1967; 11: 3–15
  • Tanford C. Physical Chemistry of Macromolecules. John Wiley, New York 1961; 275–316
  • Zimm B H. Apparatus and methods for measurement and interpretation of the angular variation of light scattering: Preliminary results in polystyrene solutions. J Chem Phys 1948; 16: 1099–1116
  • Mantle M, Forstner J F. The effects of delipidation on the major antigenic determinants of purified human intestinal mucin. Biochem Cell Biol 1986; 64: 223–228
  • Slomiany B L, Galicki N I, Kojima K, Slomiany A. Glyceroglucolipids of the mucous barrier of dog stomach. Biochim Biophys Acta 1981; 665: 88–91
  • Slomiany A, Witas F, Aono M, Slomiany B L. Covalently linked fatty acids in gastric mucus glycoprotein of cystic fibrosis patients. J Biol Chem 1983; 258: 8535–8538
  • Woodward H, Horsey B, Bhavanandan V P, Davidson E A. Isolation purification and properties of respiratory mucus glycoproteins. Biochemistry 1982; 21: 694–701
  • Sheehan J K, Carlstedt I. The effect of guanidinium chloride on the behavior of human cervical mucus glycoproteins. Evidence for unfolding regions of ordered structure in 6 M guanidinium chloride. Biochem J 1984; 221: 499–504
  • Carlstedt I, Lingren H, Sheehan J K. The macromolecular structure of human cervial mucus glycoproteins. Biochem J 1983; 213: 427–435
  • Roussel P. Glycoproteins of CF mucus. Cystic Fibrosis: Horizons, D. Lawson. John Wiley, Chichester 1984; 69–83
  • Bloomfield V A. Hydrodynamic properties of mucous glycoproteins. Biopolymers 1983; 22: 2141–2154
  • Mikkelsen A, Stokke B T, Christensen B E, Edgewater A. Flexibility and length of human bronchial mucin studied using low-shear viscometry, birefringence relaxation analysis and electron microscopy. Biopolymers 1985; 24: 1683–1704
  • Shalhamer J H, Marom Z, Logun C, Kaliner M. Human respiratory mucous glycoproteins. Exp Lung Res 1984; 7: 149–162
  • Geiduschek E P, Holtzer H. Application of light scattering to biological systems. Adv Biol Med Phys 1958; 6: 431
  • Rose M C, Voter W A, Brown C F, Kaufman B. Structural features of human tracheobronchial mucus glycoprotein. Biochem J 1984; 222: 371–377
  • Slayter H S, Lamblin G, Le Treit A, Galabert C, Houdret N, Degand P, Roussel P. Complex structure of human bronchial mucus glycoproteins. Eur J Biochem 1984; 142: 209–218
  • Harding S E, Rose A J, Creeth J M. Further evidence for a flexible and highly expanded spheroidal model for mucus glycoproteins in solution. Biochem J 1983; 209: 893–896

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