1
Views
2
CrossRef citations to date
0
Altmetric
Original Article

Resistance of Hamster Bronchiolar Epithelium to Neutrophil Elastase: Investigation by Cell Surface Lectin Cytochemistry

, , , , &
Pages 115-129 | Received 05 Mar 1991, Accepted 31 May 1991, Published online: 02 Jul 2009

References

  • Snider G L, Lucey E C, Christensen T G, Stone P J, Calore J D, Catanese A, Franzblau C. Emphysema and bronchial secretory cell metaplasia induced in hamsters by human neutrophil products. Am Rev Respir Dis 1984; 129: 155–160
  • Breuer R, Christensen T G, Lucey E C, Stone P J, Snider G L. Quantitative study of secretory cell metaplasia induced by human neutrophil elastase in the large bronchi of hamsters. J Lab Clin Med 1985; 105: 635–640
  • Breuer R, Christensen T G, Lucey E C, Stone P J, Snider G L. An ultrastructural morphometric analysis of elastase‐treated hamster bronchi shows discharge followed by progressive accumulation of secretory granules. Am Rev Respir Dis 1987; 136: 698–703
  • Christensen T G, Breuer R, Hornstra L J, Lucey E C, Stone P J, Snider G L. An ultrastructural study of the response of hamster bronchial epithelium to human neutrophil elastase. Exp Lung Res 1987; 13: 279–297
  • Christensen T G, Breuer R, Lucey E C, Stone P J, Snider G L. Regional difference in airway epithelial response to neutrophil elastase: tracheal secretory cells discharge and recover in hamsters that develop bronchial secretory cell metaplasia. Exp Lung Res 1989; 15: 943–959
  • Christensen T G, Breuer R, Lucey E C, Hornstra L J, Stone P J, Snider G L. Lectin cytochemistry reveals differences between hamster trachea and bronchus in the composition of epithelial surface glycoconjugates and in the response of secretory cells to neutrophil elastase. Am J Respir Cell Mol Biol 1990; 3: 61–69
  • McDowell E M, Trump B F. Histologic fixatives suitable for diagnostic light and electron microscopy. Arch Pathol Lab Med 1976; 100: 405–414
  • Christensen T G, Breuer R, Hornstra L J, Lucey E C, Snider G L. The ultrastructure of hamster bronchial epithelium. Exp Lung Res 1987; 13: 253–277
  • Zar J H. Biostatistical Analysis. Prentice‐Hall, Englewood Cliffs, NJ 1984
  • Damjanov I. Lectin cytochemistry and histochemistry. Lab Invest 1987; 57: 5–20
  • Geleff S, Bock P, Stockinger L. Lectin‐binding affinities of the epithelium in the respiratory tract: a light microscopical study of ciliated epithelium in rat, guinea pig, and hamster. Acta Histochem 1986; 78: 83–95
  • Schulte B A, Spicer S S. Light microscopic histochemical detection of sugar residues in secretory glycoproteins of rodent and human tracheal glands with lectin‐horseradish peroxidase conjugates and the galactose oxidase‐Schiff sequence. J Histochem Cytochem 1983; 31: 391–403
  • Spicer S S, Schulte B A, Thomopoulos G N. Histochemical properties of the respiratory tract epithelium in different species. Am Rev Respir Dis 1983; 128: s20–s26
  • Ito T, Nagahara N, Ogawa T, Inayama Y, Kanisawa M. Lectin binding to the luminal surface of distal airway epithelial cells of rodents. J Electron Microsc 1985; 34: 381–388
  • Watanabe M, Muramatsu T, Shirane H, Ugai K. Discrete distribution of binding sites for Dolichos biflorus agglutinin (DBA) and for peanut agglutinin (PNA) in mouse organ tissues. J Histochem Cytochem 1981; 29: 779–790
  • Castells M T, Ballesta J, Pastor L M, Madrid J F, Marin J A. Histochemical characterization of glycoconjugates in the epithelium of the extrapulmonary airways of several vertebrates. Histochemical J 1990; 22: 24–35
  • Mariassy A T, Plopper C G, St. George J A, Wilson D W. Tracheobronchial epithelium of the sheep, IV: lectin histochemical characterization of secretory epithelial cells. Anat Rec 1988; 222: 49–59
  • Lhermitte M, Lamblin G, Degand P, Roussel P, Mazzuca M. Affinity of bronchial secretion glycoproteins and cells of human bronchial mucosa for Ricinus communis lectins. Biochimie 1977; 59: 611–620
  • Mazzuca M, Lhermitte M, Lafitte J ‐J, Roussel P. Use of lectins for detection of glycoconjugates in the glandular cells of the human bronchial mucosa. J Histochem Cytochem 1982; 30: 956–966
  • Huet C, Herzberg M. Effects of enzymes and EDTA on ruthenium red and concanavalin A labeling of the cell surface. J Ultrastruct Res 1973; 42: 186–199
  • Gasic G, Gasic T. Removal and regeneration of the cell coating in tumour cells. Nature 1962; 196: 170–175
  • Cook G MW, Heard D H, Seaman G VF. A sialomucopeptide liberated by trypsin from the human erythrocyte. Nature 1960; 188: 1011–1012
  • Kornfeld S, Kornfeld R. Solubilization and partial characterization of a phytohemagglutinin receptor site from human erythrocytes. Proc Natl Acad Sci USA 1969; 63: 1439–1446
  • Kim K C, Wasano K, Niles R M, Schuster J E, Stone P J, Brody J S. Human neutrophil elastase releases cell surface mucins from primary cultures of hamster tracheal epithelial cells. Proc Natl Acad Sci USA 1987; 84: 9304–9308
  • Varsano S, Basbaum C B, Forsberg L S, Borson D B, Caughey G, Nadel J A. Dog tracheal epithelial cells in culture synthesize sulfated macromolecular glycoconjugates and release them from the cell surface upon exposure to extracellular proteinases. Exp Lung Res 1987; 13: 157–184
  • Breuer R, Christensen T G, Niles R M, Stone P J, Snider G L. Human neutrophil elastase causes glycoconjugate release from the epithelial cell surface of hamster trachea in organ culture. Am Rev Respir Dis 1989; 139: 779–782
  • Christensen T G, Korthy A L, Snider G L, Hayes J A. Irreversible bronchial goblet cell metaplasia in hamsters with elastase‐induced panacinar emphysema. J Clin Invest 1977; 59: 397–404
  • Breuer R, Lucey E C, Stone P J, Christensen T G, Snider G L. Proteolytic activity of human neutrophil elastase and porcine pancreatic trypsin causes bronchial secretory cell metaplasia in hamsters. Exp Lung Res 1985; 9: 167–175
  • Lucey E C, Stone P J, Breuer R, Christensen T G, Calore J D, Catanese A, Franzblau C, Snider G L. Effect of combined human neutrophil cathepsin G and elastase on induction of secretory cell metaplasia and emphysema in hamsters, with in vitro observations on elastolysis by these enzymes. Am Rev Respir Dis 1985; 132: 362–366
  • Christensen T G, Lucey E C, Breuer R, Snider G L. Acid‐induced secretory cell metaplasia in hamster bronchi. Environ Res 1988; 45: 78–90
  • Asmundsson T, Kilburn K H, McKenzie W N. Injury and metaplasia of airway cells due to SO2. Lab Invest 1973; 29: 41–53
  • McDowell E M, DeSanti A M, Newkirk C, Strum J M. Effects of vitamin A‐deficiency and inflammation on the conducting airway epithelium of Syrian golden hamsters. Virchows Archiv B Cell Pathol 1990; 59: 231–242
  • Reid L. An experimental study of hypersecretion of mucus in the bronchial tree. Br J Exp Pathol 1963; 44: 437–445
  • Lamb D, Reid L. Mitotic rates, goblet cell increase and histochemical changes in mucus in rat bronchial epithelium during exposure to sulphur dioxide. J Pathol Bacteriol 1968; 96: 97–111
  • Chakrin L W, Saunders L Z. Experimental chronic bronchitis: pathology in the dog. Lab Invest 1974; 30: 145–154
  • Spicer S S, Chakrin L W, Wardell J R. Effect of chronic sulfur dioxide inhalation on the carbohydrate histochemistry and histology of the canine respiratory tract. Am Rev Respir Dis 1974; 110: 13–24
  • Schlesinger R B, Naumann B D, Chen L C. Physiological and histological alterations in the bronchial mucociliary clearance system of rabbits following intermittent oral or nasal inhalation of sulfuric acid mist. J Toxicol Environ Health 1983; 12: 441–465
  • Kim K C, Opaskar‐Hincman H, Bhaskar K R. Secretions from primary hamster tracheal surface epithelial cells in culture: mucin‐like glycoproteins, proteoglycans, and lipids. Exp Lung Res 1989; 15: 299–314
  • Rao N V, Kennedy T P, Rao G, Ky N, Hoidal J R. Sulfated polysaccharides prevent human leukocyte elastase‐induced acute lung injury and emphysema in hamsters. Am Rev Respir Dis 1990; 142: 407–412
  • Ebert R V, Terracio M J. The bronchiolar epithelium in cigarette smokers: observations with the scanning electron microscope. Am Rev Respir Dis 1975; 111: 4–11
  • Cosio M G, Hale K A, Niewoehner D E. Morphologic and morphometric effects of prolonged cigarette smoking on the small airways. Am Rev Respir Dis 1980; 122: 265–271
  • Wright J L, Lawson L M, Pare P D, Wiggs B J, Kennedy S, Hogg J C. Morphology of peripheral airways in current smokers and ex‐smokers. Am Rev Respir Dis 1983; 127: 474–477
  • Thompson A B, Daughton D, Robbins R A, Ghafouri M A, Oehlerking M, Rennard S I. Intraluminal airway inflammation in chronic bronchitis: characterization and correlation with clinical parameters. Am Rev Respir Dis 1989; 140: 1527–1537
  • Ohlsson K, Ohlsson I. The extracellular release of granulocyte collagenase and elastase during phagocytosis and inflammatory processes. Scand J Haematol 1977; 19: 145–152

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.