In Vitro Effects of Hyperoxia on Alveolar Type II Pneumocytes: Inhibition of Glutathione Synthesis Increases Hyperoxic Cell Injury

References

• Crapo JD, Barry BE, Foscue HA, Shelburne J. Structural and biochemical changes in rat lungs occurring during exposures to lethal and adaptive doses of oxygen. Am Rev Respir Dis 1980; 122: 123–143
   PubMed Web of Science ®Google Scholar
• Freeman BA, Mason RJ, Williams MC, Crapo JD. Antioxidant enzyme activity in alveolar type II cells after exposure of rats to hyperoxia. Exp Lung Res 1986; 10: 203–222
   PubMed Web of Science ®Google Scholar
• Holm BA, Matalon S, Finkelstein JN, Notter RH. Type II pneumocyte change during hyperoxic lung injury and recovery. J Appl Physiol 1988; 65: 2672–2678
   PubMed Web of Science ®Google Scholar
• Gross NJ, Smith DM. Impaired surfactant phospholipid metabolism in hyperoxic mouse lungs. J Appl Physiol 1981; 51: 1198–1203
   PubMed Web of Science ®Google Scholar
• Simon LM, Raffin TA, Douglas W HJ. Effects of high oxygen exposure on bioenergetics in isolated type II pneumocytes. J Appl Physiol Respir Environ Physiol 1979; 47: 98–103
   PubMed Web of Science ®Google Scholar
• Haagsman HP, Schuurmans EA, Batenburg JJ, Van Golde LM. Phospholipid synthesis in isolated alveolar type II cells exposed in vitro to paraquat and hyperoxia. Biochem J 1987; 245: 119–126
   PubMed Web of Science ®Google Scholar
• Forman HJ, Fisher AB. Antioxidant enzymes of rat granular pneumocytes: constitutive levels and effect of hyperoxia. Lab Invest 1981; 45: 1–6
   PubMed Web of Science ®Google Scholar
• Panus PC, Matalon S, Freeman BA. Responses of type II pneumocyte antioxidant enzymes to normoxic and hyperoxic culture. In vitro Cell Dev Biol 1989; 25: 821–829
   PubMed Web of Science ®Google Scholar
• Aerts C, Voisin C, Wallaert B. Type II alveolar epithelial cell in vitro culture in aerobiosis. Eur Respir J 1988; 1: 738–747
   PubMed Web of Science ®Google Scholar
• White CW, Repine JE. Pulmonary antioxidant defense mechanisms. Exp Lung Res 1985; 8: 81–96
   PubMed Web of Science ®Google Scholar
• Sun JD, Pickrell JA, Harkema JR, McLaughlin SI, Hahn FF, Henderson RF. Effects of buthionine sulfoximine on the development of ozone-induced pulmonary fibrosis. Exp Mol Pathol 1988; 49: 254–266
   PubMed Web of Science ®Google Scholar
• Deneke SM, Lynch BA, Fanburg BL. Effects of low protein diets or feed restriction on rat lung glutathione and oxygen toxicity. J Nutr 1985; 115: 726–732
   PubMed Web of Science ®Google Scholar
• Deneke SM, Lynch BA, Fanburg BL. Transient depletion of lung glutathione by diethylmaleate enhances oxygen toxicity. J Appl Physiol 1985; 58: 571–574
   PubMed Web of Science ®Google Scholar
• Griffith OW, Meister A. Potent and specific inhibitors of glutathione synthesis by buthionine sulfoximine (S-N-butyl homocystein sulfiximine). J Biol Chem 1979; 254: 7558–7560
   PubMed Web of Science ®Google Scholar
• Kikkawa V, Yoneda K. The type II epithelial cell of the lung, I: method of isolation. Lab Invest 1974; 30: 76–84
   PubMed Web of Science ®Google Scholar
• Koss LG. The Papanicolaou stain. Diagnostic Cytology and Its Histopathologic Basis, LG Koss. Lippincott, Philadelphia 1979; 1211–1222
   Google Scholar
• Voisin C, Aerts C, Jakubczak E, Tonnel AB. La culture cellulaire en phase gazeuse: un nouveau modele experimental d'etude in vitro des activites des macrophages. Bull Eur Physiopathol Respir 1977; 13: 69–82
   PubMedGoogle Scholar
• McElroy WD, Seliger HH. The chemistry of light emission. Adv Enzymol 1969; 25: 119–123
   Google Scholar
• Jakubczak E, Leclerc H. Etude critique des methodes d'extraction de l'ATP bactérien en vue de son dosage par la methode de bioluminescence. Regard Biochim 1978; 2: 14–19
   Google Scholar
• Bergmeyer HU, Garvehn K. Methods of Enzymatic Analysis, Vol 2, 3d ed. Academic, New York 1978; 233
   Google Scholar
• McCord J, Fridovich I. Superoxide dismutase: an enzymatic function for erythrocuprein (hemocuprein). J Biol Chem 1969; 244: 6049–6052
   PubMed Web of Science ®Google Scholar
• Crapo JD, McCord JM. Oxygen-induced changes in pulmonary superoxide dismutase assayed by antibody titrations. Am J Physiol 1976; 231: 1196–1203
   PubMed Web of Science ®Google Scholar
• Beers RP, Sizer IW. Spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J Biol Chem 1952; 196: 133–140
   Google Scholar
• Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967; 70: 158–169
   PubMed Web of Science ®Google Scholar
• Holmes B, Park BH, Malawista SE, Quie PG, Nelson DL, Good RA. Chronic granulomatous disease in females: a deficiency of leukocyte in glutathione peroxidase. N Engl J Med 1970; 283: 217–221
   PubMed Web of Science ®Google Scholar
• Griffith OW. Determination of glutathione and glutathione disulfide using glutathione reductase and 2 vinylpyridine. Anal Biochem 1980; 106: 207–212
   PubMed Web of Science ®Google Scholar
• Gremy F, Salmon D. Bases statistiques pour la recherche medical et biologique. Dunod, Paris 1969
   Google Scholar
• Crapo JD, Tierney DF. Superoxide dismutase and pulmonary oxygen toxicity. Am J Physiol 1974; 226: 1401–1407
   PubMed Web of Science ®Google Scholar
• Frank L, Bucher JR, Roberts RJ. Oxygen toxicity in neonatal and adult animals of various species. J Appl Physiol 1978; 45: 699–704
   PubMed Web of Science ®Google Scholar
• Slade R, Stead AG, Graham JA, Hatch GE. Comparison of lung antioxidant levels in human and laboratory animals. Am Rev Respir Dis 1985; 131: 742–746
   PubMed Web of Science ®Google Scholar
• Bryant CL, Jenkinson SG. Species variations in lung antioxidant enzyme activities. J Appl Physiol 1987; 63: 597–602
   PubMed Web of Science ®Google Scholar
• Baker RR, Holm BA, Panus PC, Matalons S. Development of O2 tolerance in rabbits with no increase in antioxidant enzymes. J Appl Physiol 1989; 66: 1679–1684
   PubMed Web of Science ®Google Scholar
• Tanswell AK, Freeman BA. Differentiation - arrested rat fetal lung in primary monolayer cell culture, III: antioxidant enzyme activity. Exp Lung Res 1984; 6: 149–158
   PubMed Web of Science ®Google Scholar
• Kinnula VL, Chang L, Everitt JI, Crapo JD. Oxidants and antioxidants in alveolar epithelial type II cells: in situ, freshly isolated and culture cells. Am J Physiol (Lung Cell Mol Physiol 6) 1982; 262: L69–L77
   Google Scholar
• Michiels C, Remacle J. Use of the inhibition of enzymatic antioxidant systems in order to evaluate their physiological importance. Eur J Biochem 1988; 177: 435–444
   PubMedGoogle Scholar
• Shan X, Aw TY, Jones DP. Glutathione-dependent protection against oxidative injury. Pharmacol Ther 1990; 47: 61–71
   PubMed Web of Science ®Google Scholar
• Griffith OW, Meister A. Glutathione: interorgan translocation, turnover and metabolism. Proc Natl Acad Sci USA 1979; 76: 5606–5616
   PubMed Web of Science ®Google Scholar
• Meister A, Anderson ME. Glutathione. Am Rev Biochem 1983; 52: 711–760
   PubMed Web of Science ®Google Scholar
• Deneke SM, Fanburg BL. Regulation of cellular glutathione. Am J Physiol (Lung Cell Mol Physiol) 1989; LL163–L173
   Google Scholar
• Kimball RE, Reddy K, Peirce TH, Schwartz W, Mustafa MG, Cross CE. Oxygen toxicity: augmentation of antioxidant defense mechanism on rat lung. Am J Physiol 1976; 230: 1425–1431
   PubMed Web of Science ®Google Scholar
• Jenkinson SG, Black RD, Lawrence RA. Glutathione concentration in rat lung bronchoalveolar lavage fluid: effects of hyperoxia. J Lab Clin Med 1988; 112: 345–351
   PubMed Web of Science ®Google Scholar
• Deneke SM, Steiger V, Fanburg BL. Effects of hyperoxia on glutathione levels and glutamic acid uptake in endothelial cells. J Appl Physiol 1987; 63: 1966–1971
   PubMed Web of Science ®Google Scholar
• Rister M, Wustrow C. Effect of hyperoxia on reduced glutathione in alveolar macrophages and polymorphonuclear leukocytes. Res Exp Med 1985; 185: 445–450
   PubMedGoogle Scholar
• Phelps DT, Deneke SM, Baxter DF, Fanburg BL. Erythrocytes fail to induce glutathione in response to diethyl maleate or hyperoxia. Am J Physiol (Lung Cell Mol Physiol) 1989; 257: L272–L276
   PubMed Web of Science ®Google Scholar
• Gershman R, Gilber DL, Cacamise D. Effects of various substances on survival times of mice exposed to different high oxygen tensions. Am J Physiol 1958; 192: 563–571
   PubMed Web of Science ®Google Scholar
• Bulter JA, Patterson CE, Rhodes RA. Protective effect of cysteinamine on nor-mobaric hyperoxia in rats. Am Rev Respir Dis 1979; 119: 2961
   Google Scholar
• Dunbar JR, Delucia AJ, Bryant LR. Glutathione status of isolated rat lungs: effects of nitrofurantion and paraquat perfusion with normoxic and hyperoxic ventilation. Biochem Pharmacol 1984; 33: 1343–1348
   PubMed Web of Science ®Google Scholar
• Patterson CE, Bulter JA, Byrne FD, Rhodes ML. Oxidant lung injury: intervention with sulfhydryl reagents. Lung 1985; 163: 23–32
   PubMed Web of Science ®Google Scholar
• Patterson CE, Rhodes RA. Protective role of sulfhydryl reagents in oxidant lung injury. Exp Lung Res 1988; 14: 1005–1019
   PubMed Web of Science ®Google Scholar
• Van asbeck BS, Hoidal J, Vercelloti GM, Schwartz BA, Moldow CF, Jacob HS. Protective against lethal hyperoxia by tracheal insufflation of erythrocytes role of red cell glutathione. Science 1985; 227: 756–759
   PubMed Web of Science ®Google Scholar
• Smith J, Anderson J, Shamsuddin M, Hsueh W. Effect of fasting on hyperoxic lung injury in mice: the role of glutathione. Am Rev Respir Dis 1990; 141: 141–149
   PubMed Web of Science ®Google Scholar
• Reed DJ, Fariss MW. Glutathione depletion and susceptibility. Pharmacol Rev 1984; 36: 25S–33S
   PubMedGoogle Scholar
• Deneke SM, Gersshoff SN, Fanfurg BL. Potentiation of oxygen toxicity in rats by dietary protein or amino acid deficiency. J Appl Physiol 1983; 54: 147–151
   PubMed Web of Science ®Google Scholar
• Weber CA, Duncan CA, Lyons MJ, Jenkinson SG. Depletion of tissue glutathione with diethyl maleate enhances hyperbaric oxygen toxicity. Am J Physiol (Lung Cell Mol Physiol) 1990; 2: L308–L312
   Google Scholar
• Crapo JD, Douglas M, Sjostrom DK, Hasler GR, Drewr RT. The failure of aerosolized dismutase to modify pulmonary oxygen toxicity. Am Rev Respir Dis 1977; 115: 1027–1033
   PubMed Web of Science ®Google Scholar
• Padmanabhan RV, Guidapaty R, Llieneri E, Schwartz BA, Hoidal JR. Protection against pulmonary oxygen toxicity in rats by the intratracheal administration of liposome-encapsulated superoxide dismutase or catalase. Am Rev Respir Dis 1985; 132: 164–167
   PubMed Web of Science ®Google Scholar
• Buckley BJ, Tanswell AK, Freeman BA. Liposome-mediated augmentation of catalase in alveolar type II cells protects against H2O2 injury. J Appl Physiol 1987; 63: 359–367
   PubMed Web of Science ®Google Scholar
• Hagent TM, Brown LA, Jones DP. Protection against paraquat-induced injury by exogenous GSH in pulmonary alveolar type II cells. Biochem Pharmacol 1986; 35: 4537–4542
   PubMed Web of Science ®Google Scholar
• Lash LH, Hagent TM, Jones DP. Exogenous glutathione protect epithelial cells from oxidative injury. Proc Natl Acad Sci USA 1986; 83: 4641–4645
   PubMed Web of Science ®Google Scholar
• Hagent TM, Awt Y, Jones DP. Glutathione uptake and protection against oxidative injury in isolated kidney cells. Kidney Int 1988; 34: 74–81
   PubMed Web of Science ®Google Scholar
• Sies H, Graf P. Hepatic thiol and glutathione efflux under the influence of vasopressin phenylephrine and adrenaline. Biochem J 1985; 226: 545–549
   PubMed Web of Science ®Google Scholar
• Berggren M, Dawson J, Molpeus P. Glutathione biosynthesis in the isolated perfused rat lung: utilization of extracellular glutathione. FEBS Lett 1984; 176: 189–192
   PubMed Web of Science ®Google Scholar