7
Views
10
CrossRef citations to date
0
Altmetric
Original Article

Effect of a Synthetic Leukocyte Elastase Inhibitor on Thrombin-Induced Pulmonary Edema in the Rat

, , &
Pages 125-135 | Received 28 Oct 1991, Accepted 22 Jul 1992, Published online: 02 Jul 2009

References

  • Weiland JE, Davis WB, Holter JF, Mohammed JR., Dorinsky PM, Gadek JE. Lung neutrophils in the adult respiratory distress syndrome. Am Rev Respir Dis 1986; 133: 218–225
  • Janoff A. Elastase in tissue injury. Annu Rev Med 1985; 36: 207–216
  • Spragg RG, Cochrane CG. Human neutrophil elastase and acute lung injury. Acute Respiratory Failure, WM Zapol, KJ Falke. Dekker, New York 1985; 379–405
  • Tate RM, Repine JE. Neutrophils and the adult respiratory distress syndrome. Am Rev Respir Dis 1983; 128: 552–559
  • Suter S, Schaad UB, Morgenthaler JJ, Chevallier I, Schnebli HP. Fibronectin-cleaving activity in bronchial secretions of patients with cystic fibrosis. J Infect Dis 1988; 158: 89–100
  • Pison U, Seeger W, Buchhorn R, Joka T, Brand M, Obertacke U, Neuhof H, Schmit-Neuerburg K-P. Surfactant abnormalities in patients with respiratory failure after multiple trauma. Am Rev Respir Dis 1989; 140: 1033–1039
  • Ohlsson K. Granulocyte protease and their inhibitors in inflammation. Basic concept and clinical implication. Inflammation: Basis Mechanisms, Tissue Injury Principles, and Clinical Models, P Venge, A Lindborn. Almqvist & Wiksell International, Stockholm 1985; 379–392
  • Baird BR, Cheronis JC, Sandhaus RA, Berger EM, White CW, Repine JE. O2metabolites and neutrophil elastase synergistically cause edematous injury in isolated rat lungs. J Appl Physiol 1986; 61: 2224–2229
  • Cochrane CG, Spragg RG, Revak SD, Cohen AB, McGuire WW. The presence of neutrophil elastase and evidence of oxidation activity in bronchoalveolar lavage fluid of patients with adult respiratory distress syndrome. Am Rev Respir Dis 1983; 127: S25–S27
  • Idell S, Kucich U, Fein A, Kueppers F, James HL, Walsh PN, Weinbaum G, Colman RW, Cohen AB. Neutrophil elastase-releasing factors in bronchoalveolar lavage from patients with adult respiratory distress syndrome. Am Rev Respir Dis 1985; 132: 1098–1105
  • Lee CT, Fein AM, Lippman M, Holtzman H, Kimbel P, Weinbaum G. Elasto-lytic activity in pulmonary lavage fluid from patients with adult respiratory distress syndrome. N Engl J Med 1981; 304: 192–196
  • McGuire WW, Spragg RG, Cohen AB, Cochrane CG. Studies on the pathogenesis of the adult respiratory distress syndrome. J Clin Invest 1982; 69: 543–553
  • Morgan L, Kucich U, Dershaw B, Lippman M, Rosenbloom J, Weinbaum G, Fein A. Elastin degradation in the adult respiratory distress syndrome. Am Rev Respir Dis 1981; 123: 93, suppl
  • Ognibene FP, Martin SE, Parker MM, Schlesinger T, Roach P, Burch C, Shelha-Mer JH, Parrillo JE. Adult respiratory distress syndrome in patients with severe neutropenia. N Engl J Med 1986; 315: 547–551
  • Sommerhoff CP, Krell RD, Williams JL, Gomes BC, Strimpler AM, Nadel JA. Inhibition of human neutrophil elastase by ICI 200,355. Eur J Pharm 1991; 193: 153–158
  • Diffang C, Saldeen T. Effect of brinase (protease I from Aspergillus oryzae) on the elimination of fibrin from the lungs and pulmonary damage in rats with induced intravascular coagulation and inhibited fibrinolysis. Thromb Res 1976; 9: 611–622
  • Gerdin B, Diffang S, Saldeen T. Pulmonary insufficiency in the rat after intravascular coagulation and inhibition of fibrinolysis: studies on some pathogenic mechanisms. Eur Surg Res 1981; 13: 402–413
  • Arfors K-E, Busch C, Jakobson S, Lindquist O, Malmberg P, Rammer L, Saldeen T. Pulmonary insufficiency following intravenous infusion of thrombin and aminomethyl-cyclohexane-carboxylic acid (tranexamic acid) in the dog. Acta Chir Scand 1972; 138: 445–452
  • Lundberg C, Arfors K-E. Polymorphonuclear leukocyte accumulation in inflammatory dermal sites as measured by 51Cr-labelled cells and myeloperoxidase. Inflammation 1983; 7: 247–255
  • Wallin R, Saldeen T. A specific radioimmunoassay for determination of peptides derived from elastase degradation of human fibrin(ogen). Acta Univ Upsaliensis 1987; 102: 1–26
  • Crapo JD. Morphologic changes in pulmonary oxygen toxicity. Annu Rev Physiol 1986; 48: 721–731
  • Wallin R, Saldeen K, Belew M, Ohlsson K, Saldeen T. Purification and characteristics of a vasoactive peptide derived from elastase degradation of human fibrin(ogen). Fibrinogen-Structural Variants and Interactions 1985; 3: 289–300
  • Dinerman JL, Mehta JL, Saldeen T GP, Emerson S, Wallin R, Davda R, Davidson A. Increased neutrophil elastase release in unstable angina pectoris and acute myocardial infarction. J Am Coll Cardiol 1990; 15: 1559–1563
  • Sandler H, Gerdin B. Pulmonary insufficiency in the rat after intravascular coagulation and inhibition of fibrinolysis, 2: studies on the role of polymorphonuclear leukocytes. Acta Univ Upsaliensis 1985; 17: VII 1–VII 12
  • Hatherill JR, Raffin TA. Diagnosis and management of the adult respiratory distress syndrome. Compr Ther 1989; 15: 21–27
  • Gerdin B, Shadier H, Saldeen T. Pulmonary insufficiency in the rat after intravascular coagulation and inhibition of fibrinolysis, 2: investigations on edema formation and morphology. Eur Surg Res 1982; 14: 252–261
  • Miyamoto K, Hishinuma I, Nagakawa J, Nagoka N, Yamanaka T, Wakabayashi T. Effects of E-3123, a new protease inhibitor, on several protease activities and on experimental acute pancreatitis. Nippon Yakurigaku Zasshi 1988; 91(5): 285–293
  • Zaslow MC, Clark RA, Stone PJ, Calore JD, Snider GL, Franzblau C. Human neutrophil elastase does not bind to alpha 1-protease inhibitor that has been exposed to activated human neutrophils. Am Rev Respir Dis 1983; 128L: 434–439

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.