Elastase Causes Secretory Discharge in Bronchi of Hamsters with Elastase-Induced Secretory Cell Metaplasia

References

• Breuer R, Christensen TG, Lucey EC, Stone PJ, Snider GL. A quantitative study of secretory cell metaplasia induced by human neutrophil elastase in the large bronchi of hamsters. J Lab Clin Med 1985; 105: 635–640
   PubMed Web of Science ®Google Scholar
• Breuer R, Christensen TG, Lucey EC, Stone PJ, Snider GL. An ultrastructural morphometric analysis of elastase treated hamster bronchi shows discharge followed by progressive accumulation of secretory granules. Am Rev Respir Dis 1987; 136: 698–703
   PubMed Web of Science ®Google Scholar
• Christensen TG, Breuer R, Hornstra LJ, Lucey EC, Stone PJ, Snider GL. An ultrastructural study of the response of hamster bronchial epithelium to human neutrophil elastase. Exp Lung Res 1987; 13: 279–297
   PubMed Web of Science ®Google Scholar
• Lucey EC, Stone PJ, Christensen TG, Breuer R, Snider GL. An 18 month study of the effects of hamster lungs on intratracheally administered human neutrophil elastase. Exp Lung Res 1988; 14: 671–686
   PubMed Web of Science ®Google Scholar
• Martodam RR, Baugh RJ, Twumasi DY, Liener IE. A rapid procedure for the large scale purification of elastase and cathepsin G from human sputum. Prep Biochem 1979; 9: 15–31
   PubMed Web of Science ®Google Scholar
• Lucey EC, Stone PJ, Breuer R, Christensen TG, Calore JD, Catanese A, Franzblau C, Snider GL. Effect of combined human neutrophil cathepsin G and elastase on induction of secretory cell metaplasia and emphysema in hamsters, with in vitro observations on elastrolysis by these enzymes. Am Rev Respir Dis 1985; 132: 362–366
   PubMed Web of Science ®Google Scholar
• McDowell EM, Trump BF. Histologic fixatives suitable for diagnostic light and electron microscopy. Arch Pathol Lab Med 1976; 100: 405–414
   PubMed Web of Science ®Google Scholar
• Breuer R, Zajicek G, Christensen TG, Lucey EC, Snider GL. Cell kinetics of normal adult hamster bronchial epithelium in the steady state. Am J Respir Cell Mol Biol 1990; 2: 51–58
   PubMed Web of Science ®Google Scholar
• Brownlee KA. Statistical Theory and Methodology, 2d ed. Wiley, New York 1967; 300–301
   Google Scholar
• Snedecor GW, Cochran WG. Statistical Methods, 6th ed. Iowa State University Press, Ames, IA 1967; 258–298
   Google Scholar
• Christensen TG, Korthy AL, Snider GL, Hayes JA. Irreversible bronchial goblet cell metaplasia in hamster with elastase induced panacinar emphysema. J Clin Invest 1977; 59: 397–404
   PubMed Web of Science ®Google Scholar
• Christensen TG, Lucey EC, Breuer R, Snider GL. Acid induced secretory cell metaplasia in hamster bronchi. Environ Res 1988; 45: 78–90
   PubMed Web of Science ®Google Scholar
• McDowell EM, DeSanti AM, Newkirk C, Strum JM. Effects of vit A deficiency and inflammation of the conducting airway epithelium of Syrian golden hamsters. Virchows Archiv B Cell Pathol 1990; 59: 231–242
   Google Scholar
• Hayes JA, Christensen TG. Bronchial mucus hypersecretion induced by elastase in hamsters: ultrastructural appearances. J Pathol 1978; 125: 25–31
   PubMed Web of Science ®Google Scholar
• Wells AB. The kinetics of cell proliferation in the tracheobronchial epithelium of rats with and without chronic respiratory disease. Cell Tissue Kinet 1970; 3: 186–206
   Google Scholar
• Boren HG, Paradise LJ. Cytokinetics of lung. Pathogenesis and Theory of Lung Cancer, C Harris. Dekker, New York 1978; 369–418
   Google Scholar
• Breuer R, Christensen TG, Niles RM, Stone PJ, Snider GL. Human neutrophil elastase causes glycoconjugate release from the epithelial cell surface of hamster trachea in organ culture. Am Rev Respir Dis 1989; 139: 779–782
   PubMed Web of Science ®Google Scholar
• Kim RC, Wasano K, Niles RM, Schuster JE, Stone PJ, Brody JS. Human neutrophil elastase releases cell surface mucins from primary cultures of hamster tracheal epithelial cells. Proc Natl Acad Sci USA 1987; 84: 9304–9308
   PubMed Web of Science ®Google Scholar
• Varsano S, Basbaum CB, Forsberg LS, Borson DB, Caughey G, Nadel JA. Dog tracheal epithelial cells in culture synthesize sulfated macromolecular glycocon-jugates and release them from the ceil surface upon exposure to extracellular proteinases. Exp Lung Res 1987; 13: 157–184
   PubMed Web of Science ®Google Scholar
• Klinger JD, Tandler B, Liedtke CM, Boat TF. Proteinases of Pseudomonas aeruginosa evoke mucin release by tracheal epithelium. J Clin Invest 1984; 74: 1669–1678
   PubMed Web of Science ®Google Scholar
• Sommerhoff CP, Nadel JA, Basbaum CB, Caughey GH. Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells. J Clin Invest 1990; 85: 682–689
   PubMed Web of Science ®Google Scholar
• Thompson AB, Daughton D, Robbins RA, Ghafouri MA, Oehlerking M, Rennard SI. Intraluminal airway inflammation in chronic bronchitis: characterization and correlation with clinical parameters. Am Rev Respir Dis 1989; 140: 1527–1537
   PubMed Web of Science ®Google Scholar
• Piccioni PD, Peona V, Kramps JA, Rudolphus A, Bulgheroni A, Luisetti M. Antileukoprotease plays a major role in the proteinase activity of sputum sol-phases from chronic bronchitic patients. Am Rev Respir Dis 1991; 143: A322
   Google Scholar
• Wright J, Lawson L, Pare P, Wiggs B, Kennedy S, Hogg J. Morphology of peripheral airways in current smokers and ex-smokers. Am Rev Respir Dis 1983; 127: 474–477
   PubMed Web of Science ®Google Scholar
• DeWater R, Williams L NA, Van Maijen G NP, Franken C, Fransen J AM, Dijkman JH, Kramps JA. Ultrastructural localization of bronchial antileukopro-tease in central and peripheral human airways by a gold labeling technique using monoclonal antibodies. Am Rev Respir Dis 1986; 133: 882–890
   PubMed Web of Science ®Google Scholar