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Original Article

Bimodal Effect of Platelet-Activating Factor (PAF) on Airways Responsiveness in the Rabbit

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Pages 559-577 | Received 11 Jan 1993, Accepted 01 Mar 1994, Published online: 02 Jul 2009

References

  • Austen KF, Orange RP. Bronchial asthma: the possible role of chemical mediators of immediate hypersensitivity in the pathogenesis of subacute chronic disease. Am Rev Respir Dis. 1975; 112: 423–436
  • Nadel JA. Inflammation and asthma. J Allergy Clin Immunol. 1984; 73: 651–653
  • Smith HR, Henson PM. Mediators of asthma. Semin Respir Med. 1987; 8: 287–301
  • Morley J, Sanjar S, Page CP. The platelet in asthma. Lancet. 1984; 11: 1142–1144
  • Halonen M, Palmer JD, Lohman IC, McManus LM, Pinckard RN. Respiratory and circulatory alterations induced by acetyl glyceryl ether phosphorylcholine a mediator of IgE anaphylaxis in the rabbit. Am Rev Respir Dis. 1980; 122: 915–924
  • Vargaftig BB, Lefort J, Chignard M, Benveniste J. Platelet-activating factor induces a platelet-dependent bronchoconstriction unrelated to the formation of prostaglandin derivates. Eur J Pharmacol. 1980; 65: 185–192
  • Gateau O, Arnoux B, Deriz H, Viars P, Benveniste J. Acute effects of intratracheal administration of PAF-acether (platelet-activating factor) in humans. Am Rev Respir Dis. 1984; 129: A3
  • Cuss FM, Dixon C MS, Barnes PJ. Effects of inhaled platelet activating factor on pulmonary function and bronchial responsiveness in man. Lancet 1986; 11: 189–192
  • Smith LJ, Rubin AE, Patterson R. Mechanism of platelet activating factor-induced bronchoconstriction in humans. Am Rev Respir Dis. 1988; 137: 1015–1019
  • Nieminen MM, Moilanen E, Nyholm J-E. Platelet-activating factor impairs tracheobronchial transport and increases plasma leukotriene B4 in man. Eur Respir J. 1991; 4: 561–570
  • Nieminen MM, Moilanen E, Koskinen M. Inhaled budesonide fails to inhibit the PAF-induced increase in plasma leukotriene B4 in man. Br J Clin Pharmacol. 1992; 33: 645–652
  • Patterson R, Bernstein PR, Harris KE, Krell RD. Airway responses to sequential challenges with platelet activating factor and leukotriene D4 in rhesus monkeys. J Lab Clin Med. 1984; 104: 340–345
  • Chung KF, Aizawa H, Leikauf GD, Ueki IF, Evans TW, Nadel JA. Airway hyperresponsiveness induced by platelet-activating factor: role of thromboxane generation. J Pharmacol Exp Ther. 1986; 236: 580–584
  • Christman BW, Lefferts PL, Snapper JA. Effect of platelet-activating factor on aerosol histamine responsiveness in awake sleep. Am Rev Respir Dis. 1987; 135: 1267–1270
  • Anderson GP, White HL, Fennesy MR. Increased airways responsiveness to histamine induced by platelet activating factor in the guinea pig: possible role of lipoxygenase metabolites. Agents Actions 1988; 24: 1–7
  • Nieminen MM, Hill M, Irvin CG. Body temperature modulates the effect of platelet-activating factor (PAF) on airways responsiveness in the rabbit. Agents Actions 1991; 32: 173–181
  • Heffner JE, Shoemaker SA, Canham EM. Acetyl glyceryl ether phosphorylcholine-stimulated human platelets cause pulmonary hypertension and edema in isolated rabbit lungs: role of thromboxane A2. J Clin Invest. 1983; 71: 351–357
  • Mojarad M, Hamasaki Y, Said SI. Platelet activating factor increases pulmonary microvascular permeability and induces pulmonary edema. Bull Eur Physiopathol Respir. 1983; 19: 253–256
  • O'Flaherty JT, Wykle RL, Miller CH. 1-0-Alkyl-sn-glyceryl-3-phosphorylcholines: a novel class of neutrophil stimulants. Am J Pathol. 1981; 103: 70–78
  • Wardlaw AJ, Moqbel R, Cromwell O, Kay AB. Platelet-activating factor: a potent chemotactic and chemokinetic factor for human eosinophils. J Clin Invest. 1986; 78: 1701–1706
  • Voelkel NF, Worthen S, Reeves JT, Henson PM, Murphy RC. Nonimmunological production of leukotrienes induced by platelet-activating factor. Science 1982; 218: 286–289
  • O'Flaherty JT. Neutrophil degranulation: evidence pertaining to its mediation by the combined effects of leukotriene B4, platelet-activating factor, and 5-HETE. J Cell Physiol. 1985; 122: 229–239
  • Fauler J, Sielhorst G, Frohlich JC. Platelet-activating factor induces the production of leukotrienes by human monocytes. Biochim Biophys Acta. 1989; 1013: 80–85
  • Page CP, Guerreiro D, Sanjar S, Morley J. Platelet activating factor (PAF-acether) may account for late-onset reactions to allergen inhalation. Agents Actions 1985; 16: 30–32
  • Chignard M, Le Couedic JP, Tence M, Vargaftig BB, Benveniste J. The role of platelet-activating factor in platelet aggregation. Nature 1979; 179: 799–800
  • Clark PO, Hanahan DJ, Pinckard RN. Physical and chemical properties of platelet-activating factor obtained from human neutrophils and monocytes and rabbit neutrophils and basophils. Biochim Biophys Acta. 1980; 628: 69–75
  • Lee TC, Lenihan DJ, Malone B, Roddy LL, Wasserman SI. Increased biosynthesis of platelet activating factor in activated human eosinophils. J Biol Chem 1984; 259: 5526–5530
  • Henson PM. Extracellular and intracellular activities of platelet activating factor. New Horizons in Platelet Activating Factor Research, CM Winslow, ML Lee. Wiley, New York 1987
  • Kravis TC, Henson PM. IgE-induced release of a platelet-activating factor from rabbit lung. J Immunol. 1975; 115: 1677–1681
  • Arnoux B, Duval D, Benveniste J. Release of platelet-activating factor (PAF-acether) from alveolar macrophages by the calcium ionophore A 23187 and phagocytosis. Eur J Clin Invest. 1980; 10: 437–441
  • Chesney CM, Pifer DD, Huch KM. Desensitization of human platelets by platelet activating factor. Biochem Biophys Res Commun. 1985; 127: 24–30
  • Stimler NP, Bloor CM, Hugli TE, Wykle RL, McCall CE, O'Flaherty JT. Anaphylactic actions of platelet activating factor. Am J Pathol. 1981; 105: 64–69
  • Maridonneau-Parini I, Lagente V, Lefort J, Randon J, Russo-Marie F, Vargaftig BB. Desensitization of PAF-induced bronchoconstriction and to activation of alveolar macrophages by repeated inhalation of PAF in the guinea pig. Biochem Biophys Res Commun. 1985; 131: 42–49
  • McMurtry IF, Morris KG. Platelet-activating factor causes pulmonary vasodilatation in the rat. Am Rev Respir Dis. 1986; 134: 757–762
  • Mehta K, Wargovich T, Nichols WW. Biphasic effects of platelet-activating factor on coronary blood flow in anesthetized dog. Prostaglandins Leukotrienes Med. 1986; 21: 87–95
  • Irvin CG, Dempsey JA. Role of H1 and H2 receptors in increased small airways resistance in the dog. Respir. Physiol. 1978; 35: 161–176
  • Vargaftig BB, Lefort J, Rotilio D. Route-dependent interactions between PAF-acether and guinea pig bronchopulmonary smooth muscle: relevance of cyclooxygenase mechanisms. Platelet Activating Factor and Structurally Related Ether-Lipids, INSERM Symposium 23, J Benveniste, B Arnoux. Elsevier Science, New York 1983
  • Irvin CG, Berend N, Henson PM. Airways hyperreactivity and inflammation produced by aerosolization of human C5a des arg. Am Rev Respir Dis. 1986; 134: 777–783
  • March WR, Irvin CG, Murphy KR, Behrens S BL, Larsen GL. Increases in airway reactivity to histamine and inflammatory cells in bronchoalveolar lavage after the late asthmatic response in an animal model. Am Rev Respir Dis. 1985; 131: 875–879
  • Mazzoni I, Morley J, Page CP, Sanjar S. Induction of airway hyperreactivity by platelet-activating factor in the guinea pig. J Physiol. 1985; 365: 107
  • Hopp RJ, Bewtra AK, Agrawal DK, Townley RG. Effect of platelet-activating factor inhalation on nonspecific bronchial reactivity in man. Chest 1989; 96: 1070–1072
  • Lai C KW, Jenkins JR, Polosa R, Holgate ST. Inhaled PAF fails to induce airway hyperresponsiveness to methacholine in normal human subjects. J Appl Physiol. 1990; 68: 919–926
  • Knauer KA, Lichtenstein LM, Adkinson NF, Jr, Fish JE. Platelet activation during antigen-induced airway reactions in asthmatic subjects. N Engl J Med. 1981; 304: 1404–1407
  • Behren S BL, Clark R AF, Feldsein DL. Comparison of the histopathology of the immediate and late asthmatic and cutaneous responses in a rabbit model. Chest 1985; 87: 1539–1559
  • Camussi G, Pawlowski L, Tetta C. Acute lung inflammation induced in the rabbit by local instillation of 1-0-octadecyl-2-acetyl-sn-glyceryl-3-phos-phorylcholine or of native platelet activating factor. Am J Pathol. 1983; 112: 78–88
  • Blank ML, Cress EA, Whittle T, Snyder F. In vivo metabolism of a new class of biologically active phospholipids: 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine a platelet activating-hypotensive phospholipid. Life Sci. 1981; 29: 769–775
  • Haroldsen PE, Voelkel NF, Henson JE, Henson PM, Murphy RC. Metabolism of platelet activating factor in isolated perfused late lung. J Clin Invest. 1987; 79: 1860–1867
  • Kumar R, King R LJ, Martin HM, Hanahan DJ. Metabolism of platelet activating factor (alkylacetylphosphocholine) by type II epithelial cells and fibroblasts from rat lungs. Biochim Biophys Acta. 1987; 917: 33–41

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