Enhanced Production of an Egf-Like Growth Factor by Parenchymal Macrophages Following Bleomycin-Induced Pulmonary Injury

References

• Kumar R K, Lykke A WJ. Messages and handshakes: cellular interactions in pulmonary fibrosis. Pathology 1995; 27: 18–26
   PubMed Web of Science ®Google Scholar
• Mornex J F, Leroux C, Greenland T, Ecochard D. From granuloma to fibrosis in interstitial lung diseases: molecular and cellular interactions. Eur Respir J 1994; 7: 779–785
   PubMed Web of Science ®Google Scholar
• Vanhee D, Gosset P, Wallaert B, Voisin C, Tonnel AB. Mechanisms of fibrosis in coal workers' pneumoconiosis: increased production of platelet-derived growth factor, insulin-like growth factor type I, and transforming growth factor β and relationship to disease severity. Am J Respir Crit Care Med 1994; 150: 1049–1055
   PubMed Web of Science ®Google Scholar
• Adamson I YR, Bowden DH. Pulmonary reaction to long and short asbestos fibers is independent of fibroblast growth factor production by alveolar macrophages. Am J Pathol 1990; 137: 523–529
   PubMed Web of Science ®Google Scholar
• Vignaud J M, Allam M, Martinet N, Pech M, Plenat F, Martinet Y. Presence of platelet-derived growth factor in normal and fibrotic lung is specifically associated with interstitial macrophages, while both interstitial macrophages and alveolar epithelial cells express the c-sis proto-oncogene. Am J Respir Cell Mol Biol 1991; 5: 531–538
   PubMed Web of Science ®Google Scholar
• Phan S H, Kunkel SL. Lung cytokine production in bleomycin-induced pulmonary fibrosis. Exp Lung Res 1992; 18: 29–43
   PubMed Web of Science ®Google Scholar
• Adamson I YR. Radiation enhances silica translocation to the pulmonary interstitium and increases fibrosis. Environ Health Perspect 1992; 97: 233–238
   PubMed Web of Science ®Google Scholar
• Velan G M, Kumar R K, Cohen DD. Pulmonary inflammation and fibrosis following subacute inha-lational exposure to silica: determinants of progression. Pathology 1993; 25: 282–290
   PubMed Web of Science ®Google Scholar
• Brody A R, Bonner J C, Overby L H, et al. Interstitial pulmonary macrophages produce platelet-derived growth factor that stimulates rat lung fibroblast proliferation in vitro. J Leuk Biol 1992; 51: 640–648
   PubMed Web of Science ®Google Scholar
• Madtes D K, Raines E W, Sakariassen K S, et al. Induction of transforming growth factor-α in activated human alveolar macrophages. Cell 1988; 53: 285–293
   PubMed Web of Science ®Google Scholar
• Rappolee D A, Mark D, Banda M J, Werb Z. Wound macrophages express TGF-α and other growth factors in vivo: analysis by mRNA phenotyping. Science 1988; 241: 708–712
   PubMed Web of Science ®Google Scholar
• Madtes D K, Busby H K, Strandjord T P, Clark JG. Expression of transforming growth factor-a and epidermal growth factor receptor is increased following bleomycin-induced lung injury in rats. Am J Respir Cell Mol Biol 1994; 11: 540–551
   PubMed Web of Science ®Google Scholar
• Korfhagen T H, Swantz R J, Wert S E, et al. Respiratory epithelial cell expression of human transforming growth factor-a induces lung fibrosis in transgenic mice. J Clin Invest 1994; 93: 1691–1699
   PubMed Web of Science ®Google Scholar
• Hardie W D, Kerlakian C B, Bruno M D, et al. Reversal of lung lesions in transgenic transforming growth factor-α mice by expression of mutant epidermal growth factor receptor. Am J Respir Cell Mol Biol 1996; 15: 499–508
   PubMed Web of Science ®Google Scholar
• Kumar R K, O'Grady R, Li W, Rajkovic I. Secretion of epidermal growth factor-like molecular species by lung parenchymal macrophages: induction by interferon-gamma. Growth Factors 1993; 9: 223–230
   PubMed Web of Science ®Google Scholar
• Kumar R K, Velan G M, O'Grady R. Epidermal growth factor-like activity in bronchoalveolar lavage fluid in experimental silicosis. Growth Factors 1994; 10: 163–170
   PubMed Web of Science ®Google Scholar
• Schrier D J, Kunkel R G, Phan SH. The role of strain variation in murine bleomycin-induced pulmonary fibrosis. Am Rev Respir Dis 1983; 127: 63–66
   PubMed Web of Science ®Google Scholar
• Mishell B B, Shiigi SM. Selected Methods in Cellular Immunology. Freeman, San Francisco 1980
   Google Scholar
• Bilyk N, Holt PG. The surface phenotypic characterization of lung macrophages in C3H/HeJ mice. Immunology 1991; 74: 645–651
   PubMed Web of Science ®Google Scholar
• Holt P G, Warner L A, Papadimitriou JM. Alveolar macrophages: functional heterogeneity within macrophage populations from rat lung. Aust J Exp Biol Med Sci 1982; 60: 607–618
   PubMedGoogle Scholar
• Kumar R K, O'Grady R, Li W, Smith L W, Rhodes GC. Primary culture of adult mouse lung Fibroblasts in serum-free medium: responses to growth factors. Exp Cell Res 1991; 193: 398–404
   PubMed Web of Science ®Google Scholar
• Hollander M, Wolfe DA. Nonparametric Statistical Methods. Wiley, New York 1973
   Google Scholar
• Janick-Buckner D, Ranges G E, Hacker MP. Alteration of bronchoalveolar lavage cell populations following bleomycin treatment in mice. Toxicol Appl Pharmacol 1989; 100: 465–473
   PubMed Web of Science ®Google Scholar
• Lavnikova N, Prokhorova S, Helyar I, Laskin DL. Isolation and partial characterization of subpopulations of alveolar macrophages, granulocytes, and highly enriched interstitial macrophages from rat lung. Am J Respir Cell Mol Biol 1993; 8: 384–392
   PubMed Web of Science ®Google Scholar
• Hermann F, De Vos S, Brach M, Riedel D, Lindemann A, Mertelsmann R. Secretion of granulocyte-macrophage colony-stimulating factor by human blood monocytes is stimulated by engagement of Fcγ receptors type I by solid-phase immunoglobulins requiring high-affinity Fc-Fcγ receptor type I interactions. Eur J Immunol 1992; 22: 1681–1685
   PubMed Web of Science ®Google Scholar
• Brach M A, Sott C, Kiehntopf M, Herrmann F. Expression of the transforming growth factor-α gene by human eosinophils is regulated by interleukin-3, interleukin-5, and granulocyte-macrophage colony-stimulating factor. Eur J Immunol 1994; 24: 646–650
   PubMed Web of Science ®Google Scholar
• Higashiyama S, Abraham J A, Miller J, Fiddes J C, Klagsbrun M. A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science 1991; 251: 936–939
   PubMed Web of Science ®Google Scholar
• Mroczkowski B, Reich M. Identification of biologically active epidermal growth factor precursor in human fluids and secretions. Endocrinology 1993; 132: 417–425
   PubMed Web of Science ®Google Scholar
• O'Sullivan C, Lewis C E, Harris A L, McGee JO. Secretion of epidermal growth factor by macrophages associated with breast carcinoma. Lancet 1993; 342: 148–149
   PubMed Web of Science ®Google Scholar
• Sannes P L, Burch K K, Khosla J. Immunohistochemical localization of epidermal growth factor and acidic and basic fibroblast growth factor in postnatal developing and adult rat lungs. Am J Respir Cell Mol Biol 1992; 7: 230–237
   PubMed Web of Science ®Google Scholar
• Kumar R K, O' Grady R, Di Girolamo N. Epidermal growth factor-like molecular species in normal bronchoalveolar lavage fluid. Lung 1996; 174: 171–179
   PubMed Web of Science ®Google Scholar