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Original Article

Genetics of Quantitative and Qualitative Aspects of Lung Tumorigenesis in the Mouse: Multiple Interacting Susceptibility to lung cancer (Sluc) Genes with Large Effects

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Pages 419-436 | Received 11 Mar 1998, Accepted 11 Mar 1998, Published online: 02 Jul 2009

References

  • Eng C, Ponder B A. The role of gene mutations in the genesis of familial cancers. FASEB J. 1993; 7: 910–919
  • Peto J. Genetic predisposition to cancer. Cancer Incidence in Defined Populations, J Cairns, J L Lyon, M Skolnick. CSH. 1980; 203–213, Banbury report
  • Heston W E. Genetic analysis of susceptibility to induced pulmonary tumors in mice. J Natl Cancer Inst. 1942; 3: 69–78
  • Heston W E. Inheritance of susceptibility to spontaneous pulmonary tumors in mice. J Natl Cancer Inst. 1942; 3: 79–82
  • Diwan B A, Meier H. Strain- and age-dependent transplacental carcinogenesis by l-ethyl-l-nitrosourea in inbred strains of mice. Cancer Res. 1974; 34: 764–767
  • van der Valk M A. Survival, tumor incidence and gross pathology in 33 mouse strains. Mammary Tumors in the Mouse, J Hilgers, M Sluyser. Elsevier/North-Holland Biomedical, Amsterdam 1981; 46–115
  • Parkin D M, Pisani P, Ferlay J. Estimates of the worldwide incidence of eighteen major cancers in 1985. Int J Cancer 1993; 54: 594–606
  • Pisani P, Parkin D M, Ferlay J. Estimates of the worldwide mortality from eighteen major cancers in 1985. Implications for prevention and projections of future burden. Int J Cancer 1993; 55: 891–903
  • Ryan J, Barker P E, Nesbitt M N, Ruddle F H. KRAS2 as a genetic marker for lung tumor susceptibility in inbred mice. J Natl Cancer Inst. 1987; 79: 1351–1357
  • Gariboldi M, Manenti G, Canzian F, et al. A major lung tumor susceptibility locus to murine lung carcinogenesis maps on chromosome 6. Nature Genet. 1993; 3: 132–136
  • Devereux T R, Wiseman R W, Kaplan N, et al. Assignment of a locus for mouse lung tumor susceptibility to proximal chromosome 19. Mammalian Genome. 1994; 5: 749–755
  • Festing M FW, Yang A, Malkinson A M. At least four genes and sex are associated with susceptibility to urethane-induced pulmonary adenomas in mice. Genet Res Camb. 1994; 64: 99–106
  • Manenti G, Gariboldi M, Elango R, et al. Genetic mapping of a pulmonary adenoma resistance locus (Par 1) in mouse. Nature Genet. 1996; 12: 455–457
  • You M, Yang Y, Stoner G, et al. Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids. Proc Natl Acad Sci USA. 1992; 89: 5804–5808
  • Fijneman R JA, Ophoff R A, Hart A AM, Demant P. K-ras-2 alleles, mutations, and lung tumor susceptibility in the mouse: an evaluation. Oncogene. 1994; 9: 1417–1421
  • Chen B, Johanson L, Wiest J S, Anderson M W, You M. The second intron of the K-ras gene contains regulatory elements associated with mouse lung tumor susceptibility. Proc Natl Acad Sci USA. 1994; 91: 1589–1593
  • Demant P, Hart A AM. Recombinant congenic strains: a novel tool for analyzing genetic traits determined by more than one gene. Immunogenetics. 1986; 24: 416–422
  • Jansen R C. Complex plant traits: time for polygenic analysis. Trends Plant Sci. 1996; 1: 89–94
  • Fijneman R JA, de Vries S S, Jansen R C, Demant P. Complex interactions of new quantitative trait loci, Sluc1, Sluc2, Sluc3 and Sluc4, that influence the susceptibility to lung cancer in the mouse. Nature Genet. 1996; 14: 465–467
  • Moen C JA, van der Valk M A, Snoek M, et al. The recombinant congenic strains: a novel genetic tool applied to the study of colon tumor development in the mouse. Mammalian Genome. 1991; 1: 217–227
  • Mori N, Okumoto M, van der Valk M A, et al. Genetic dissection of susceptibility to radiation-induced apoptosis of thymocytes and mapping of Rapopl, a novel susceptibility gene. Genomics. 1995; 25: 609–614
  • Lipoldova M, Kosarova M, Zajicova A, et al. Separation of multiple genes controlling the T-cell proliferative response to IL-2 and anti-CD3 using recombinant congenic strains. Immunogenetics. 1995; 41: 301–311
  • Moen C JA, Snoek M, Hart A AM, Demant P. Scc-1, a novel colon cancer susceptibility gene in the mouse: linkage to CD44 (Ly-24, Pgp-1) on chromosome 2. Oncogene. 1992; 7: 563–566
  • Moen C JA, Groot P C, Hart A AM, Snoek M, Demant P. Fine mapping of colon tumor susceptibility (Sec) genes in the mouse, different from the genes known to be somatically mutated in colon cancer. Proc Natl Acad Sci USA. 1996; 93: 1082–1086
  • van Wezel T, Stassen A PM, Moen C JA, Hart A AM, van der Valk M A, Demant P. Gene interaction and single gene effects in colon tumor susceptibility in mice. Nature Genet. 1996; 14: 468–470
  • Mori N, Okumoto M, Hart A AM, Demant P. Apoptosis susceptibility genes on mouse chromosome 9 (Rapop2) and chromosome 3 (Rapop3). Genomics. 1995; 30: 553–557
  • Krulova M, Havelkova H, Kosarova M, et al. IL-2-induced proliferative response is controlled by loci Cinda1 and Cinda2 on mouse chromosomes 11 and 12: a distinct control of the response induced by different IL-2 concentrations. Genomics. 1997; 42: 11–15
  • Havelkova H, Krulova M, Kosarova M, et al. Genetic control of T-cell proliferative response in mice linked to chromosomes 11 and 15. Immunogenetics. 1996; 44: 475–477
  • Fijneman R JA, Jansen R C, van der Valk M A, Demant P. Dissection of a complex quantitative genetic trait: multiple interactions and ten new lung cancer susceptibility loci, Sluc5 to Sluc14, Submitted
  • Oomen L CJM, van der Valk M A, Demant P. MHC and non-MHC genes in lung tumor susceptibility in the mouse: implications for the study of the different lung tumor types and their cell of origin. Exp Lung Res. 1991; 17: 283–304
  • Obata M, Nishimori H, Katsuhiro O, Lee G -H. Identification of the Par2 (pulmonary adenoma resistance) locus on mouse chromosome 18, a major genetic determinant for lung carcinogen resistance in BALB/cByJ mice. Oncogene. 1996; 13: 1599–1604
  • Kauffman S L, Alexander L, Sass L. Histologic and ultrastructural features of the Clara cell adenoma of the mouse lung. Lab Invest. 1979; 40: 708–716
  • den Engelse L, Oomen L CJM, van der Valk M A, Hart A AM, Dux A. Studies on lung tumours, V: susceptibility of mice to dimethylnitrosamine-induced tumour formation in relation to H-2 haplotype. Int J Cancer. 1981; 28: 199–208
  • Oomen L CJM, Demant P, Hart A AM, Emmelot P. Multiple genes in the H-2 complex affect differently the number and growth rate of transplacentally induced lung tumours in mice. Int J Cancer. 1983; 31: 447–454
  • Beer D G, Malkinson A M. Genetic influence on type 2 or Clara cell origin of pulmonary adenomas in urethan-treated mice. J Natl Cancer Inst. 1985; 75: 963–969
  • Heston W E, Dunn T B. Tumor development in susceptible strain A and resistant strain L lung transplants in LAF1 hosts. J Natl Cancer Inst. 1951; 11: 1057–1071
  • Shapiro J R, Kirschbaum A. Intrinsic tissue response to induction of lung transplants. Cancer Res. 1951; 11: 644–647
  • Mintz B, Custer R P, Donnelly A J. Genetic diseases and developmental defects analyzed in allophenic mice. International Review of Experimental Pathology, G W Richter, M A Epstein. Academic, New York 1971; Vol 10: 143–179
  • Heston W E. Genetics in neoplasia. Methodology in Mammalian Genetics, W J Burdette. Holden-Day, San Francisco 1963; 247–268
  • Murphy E D. Characteristic tumors. Biology of the Laboratory Mouse, E L Green. McGraw-Hill, New York 1966; 521–570
  • Dux A, Demant P. MHC-controlled susceptibility to C3H-MTV-induced mouse mammary tumors is predominantly systemic rather than local. Int J Cancer. 1987; 40: 372–377
  • Loll P J, Picot D, Garavito R M. The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase. Nature Structural Biol. 1995; 2: 637–643
  • Rosenberg L, Palmer J R, Zauber A G, Warshauer E M, Stolley P D, Shapiro S. A hypothesis: nonsteroidal anti-inflammatory drugs reduce the incidence of large-bowel cancer. J Natl Cancer Inst. 1991; 83: 355–358
  • Giardiello F M, Hamilton S R, Krush A J, et al. Treatment of colonic and rectal adenomas with sulin-dac in familial adenomatous polyposis. N Engl J Med. 1993; 328: 1313–1316
  • Jacoby R F, Marshall D J, Newton M A, et al. Chemoprevention of spontaneous intestinal adenomas in the ApcMis mouse model by the nonsteroidal anti-inflammatory drug piroxicam. Cancer Res. 1996; 56: 710–714
  • Jalbert G, Castonguay A. Effects of NSAIDs on NNK-induced pulmonary and gastric tumorigenesis in A/J mice. Cancer Lett. 1992; 66: 21–28
  • Potter M, Wax J S, Anderson A O, Nordan R P. Inhibition of plasmacytoma development in BALB/c mice by indomethacin. J Exp Med. 1985; 161: 996–1012
  • Oshima M, Dinchuk J E, Kargman S L, et al. Suppression of intestinal polyps in ApcΔ716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell. 1996; 87: 803–809
  • MacPhee M, Chepenik K P, Liddell R A, Nelson K K, Siracusa L D, Buchberg A M. The secretory phosphpolipase A2 gene is a candidate for the Mom1 locus, a major modifier of the ApcMin-induced intestinal neoplasia. Cell. 1995; 81: 957–966
  • Mock B A, Krall M M, Dosik J K. Genetic mapping of tumor susceptibility genes involved in mouse plasmacytomagenesis. Proc Natl Acad Sci USA. 1993; 90: 9499–9503
  • Poole T M, Drinkwater N R. Two genes abrogate the inhibition of murine hepatocarcinogenesis by ovarian hormones. Proc Natl Acad Sci USA. 1996; 93: 5848–5853
  • Drinkwater N P. Genetic control of hepatocarcinogenesis in C3H mice. Drug Metab Rev. 1994; 26: 201–218
  • Manenti G, Binelli G, Gariboldi M, et al. Multiple loci affect genetic predisposition to hepatocarcinogenesis in mice. Genomics. 1994; 23: 118–124
  • Shisa H, Yamada Y, Kawarai A, et al. Genetic and epigenetic resistance of SL/Ni mice to lymphomas. Jpn J Cancer Res. 1996; 87: 258–262
  • Lee G H, Bennett L M, Carabeo R A, Drinkwater N R. Identification of hepatocarcinogen-resistance genes in DBA/2 mice. Genetics. 1995; 139: 387–395
  • Fijneman R JA, Demant P. A gene for susceptibility to small intestinal cancer, ssic1 maps to the distal part of mouse chromosome 4. Cancer Res. 1995; 55: 3179–3182
  • Dietrich W, Lander E S, Smith J S, et al. Genetic identification of Mom-1 a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell. 1993; 75: 631–639
  • Nagase H, Bryson S, Cordell H, Kemp C J, Fee F, Balmain A. Distinct genetic loci control development of benign and malignant skin tumours in mice. Nature Genet. 1995; 10: 424–429
  • Gariboldi M, Manenti G, Canzian F, et al. Chromosome mapping of murine susceptibility loci to liver carcinogenesis. Cancer Res. 1993; 53: 209–211
  • Yamada Y, Shisa H, Matsushiro H, et al. T lymphomagenesis is determined by a dominant gene thymic lymphoma susceptible mouse-1 (TLSM-1) in mouse models. J Exp Med. 1994; 180: 2155–2162
  • Jacoby R F, Hohman C, Marshall D J, et al. Genetic analysis of colon cancer susceptibility in mice. Genomics. 1994; 22: 381–387
  • Pataer A, Kamoto T, Lu L -M, Yamada Y, Hiai H. Two dominant host resistance genes to pre-B lymphoma in wild-derived inbred mouse strain MSM/Ms. Cancer Res. 1996; 56: 3716–3720

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