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Original Article

Transforming Growth Factor-Beta Expression in Mouse Lung Carcinogenesis

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Pages 579-593 | Received 10 Feb 1998, Accepted 10 Feb 1998, Published online: 02 Jul 2009

References

  • Cancer Facts and Figures, 1996. American Cancer Society, Atlanta, GA 1996; 10
  • Ginsberg R J. Multimodality therapy for stage IIIA (N2) lung cancer: an overview. Chest. 1993; 103: 356s–359s
  • Malkinson A M. Primary lung tumors in mice: an experimentally manipulable model of human adenocarcinoma. Cancer Res (Suppl). 1992; 52: 2670s–2676s
  • You M, Candrian U, Maronpot R R, Stoner G D, Anderson M W. Activation of the K-ras protoonocogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse. Proc Natl Acad Sci USA. 1989; 86: 3070–3074
  • Festing M FW, Yang A, Malkinson A M. At least four genes and sex are associated with susceptibility to urethane-induced pulmonary adenomas in mice. Genet Res. 1994; 64: 99–106
  • Horio Y, Chen A, Rice P, Roth J A, Malkinson A M, Schrump D S. Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice. Mol Carcinog. 1996; 17: 217–223
  • Roberts A B, Sporn M B. The transforming growth factor-βs. Handbook of Experimental Pharmacology, M B Sporn, A B Roberts. Springer, Berlin 1990; 419–472
  • Massagure J, Cheifetz S, Laiho M, Ralph D A. Transforming growth factor-beta. Cancer Surv. 1992; 12: 81–103
  • Chiefetz S, Weatherbee J A, Tsang M L-S, et al. The transforming growth factor-beta system, a complex pattern of cross reactive ligands and receptors. Cell. 1987; 48: 409–415
  • Damstrup L, Rygaard K, Spang-Thomsen M, Poulson H S. Expression of transforming growth factor beta (TGF beta) receptors and expression of TGF beta 1, TGF beta 2, TGF-beta 3 in human small cell lung cancer cell lines. Br J Cancer. 1993; 1015–1021
  • Norgaard P, Damstrup L, Rygaard K, Spang-Thomsen M, Skovgaard H P. Growth suppression by transforming growth factor beta 1 of human small-cell lung cancer cell lines is associated with expression of the type II receptor. Br J Cancer. 1994; 69: 802–808
  • Reiss M, Sartorelli A. Regulation of growth and differentiation of human keratinocytes by type β transforming growth factor and epidermal growth factor. Cancer Res. 1987; 47: 6705–6709
  • Geiser A, Burmester J, Webbink R, Roberts A, Sporn M. Inhibition of growth by transforming growth factor-β following fusion of two non-responsive human carcinoma cell lines. J Biol Chem. 1992; 267: 2588–2593
  • Park J, Kim S -J, Bang Y -J, Park J -G, Kim N K, Roberts A B, Sporn M B. Genetic changes in the transforming growth factor β (TGF-β) type II receptor gene in human gastric carcinoma cells: correlation, with sensitivity to growth inhibition by TGF-β. Proc Natl Acad Sci USA. 1994; 91: 8772–8776
  • Markowitz S, Myerhoff L, Cooper M, Vogelstein B. A benign cultured colon adenoma bears three genetically altered colon cancer oncogenes, but progresses to tumorigeneicity and transforming growth factor-beta independence without inactivating the p53 tumor suppressor gene. J Clin Invest. 1994; 93: 1005–1013
  • Manning A, Williams A, Game S, Paraskeva C. Differential sensitivity of human colonic adenoma and carcinoma cells to transforming growth factor β (TGF β): conversion of an adenoma cell line to a tumorigenic phenotype is accompanied by a reduced response to the inhibitory effects of TGF-β. Oncogene. 1991; 6: 1471–1476
  • Jakowlew S B, Mathias A, Chung P, Moody T W. Expression of transforming growth factor fi ligand and receptor messenger RNAs in lung cancer cell lines. Cell Growth Differ. 1995; 6: 465–476
  • Chirgwin J M, Przybyla A E, MacDonald R J, Rutter W J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 1979; 18: 5294–5299
  • Church G M, Gilbert W. Genomic sequencing. Proc Natl Acad Sci USA. 1984; 80: 1991–1995
  • Qian S W, Kondaiah P, Roberts A B, Sporn M B. cDNA cloning by PCR of rat transforming growth factor-β1. Nucleic Acids Res. 1990; 8: 3059
  • Miller D A, Lee A, Pelton R W, Chen E Y, Moses H L, Derynck R. Murine transforming growth factor-β2 cDNA sequence and expression in adult tissues and embryos. Mol Endocrinol. 1989; 3: 1108–1114
  • Denhez F, Lafyatis R, Kondaiah P, Roberts A B, Sporn M B. Cloning by polymerase chain reaction of a new mouse TGF-β, TGF-β3. Growth Factors. 1990; 3: 1325–1345
  • Derynck R, Goeddel D V, Ullrich A, et al. Synthesis of messenger mRNAs for transforming growth factors alpha and β and the epidermal growth factor receptor by human tumors. Cancer Res. 1987; 47: 707–712
  • Yoshida K, Yokozaki H, Niimoto M, Ito H, Tahara E. Expression of TGF-β and procollagen type I and type III in human gastric carcinomas. Int J Cancer. 1989; 44: 394–398
  • Gomella L G, Sargent E R, Wade T P, Anglard P, Linehan W M, Kasid A. Expression of transforming growth factor alpha in normal human adult kidney and enhanced expression of transforming growth factor alpha and β1 in renal cell carcinoma. Cancer Res. 1989; 49: 6972–6975
  • Barrett P, Travers M, Luqmani Y, Coombes R C. Transforming growth factors in human breast cancer: clinical correlates. Br J Cancer. 1990; 61: 612–617
  • La Rocca R V, Park J G, Danesi R, Tacca M D, Steinberg S M, Gazdar A F. Pattern of growth factor, proto-oncogene and carcinoembryonic antigen gene expression in human colorectal carcinoma cell lines. Oncology. 1992; 49: 209–214
  • Knabbe C, Klein H, Zugmaier G, Voigt K D. Hormonal regulation of transforming growth factor β-2 expression in human prostate cancer. J Steroid Biochem Mol. Biol. 1993; 47: 137–142
  • Gold L I, Korc M. Expression of transforming growth factor-β1, 2, and 3 mRNA in human cancers. Dig Surg. 1994; 11: 150–156
  • Wrann M, Bodmer S, de Martin R, Siepl C, Hofer-Warbinek R. T cell suppressor factor from human glioblastoma cells is a 12.5 kd protein closely related to transforming growth factor-β. EMBO J. 1987; 6: 1633–1636
  • Jakowlew S B, Kondaiah P K, Flanders K C, et al. Increased coordinate expression of growth factor mRNAs accompanies viral transformation of rodent cells. Oncogene Res. 1988; 2: 135–148
  • Anzano M A, Roberts A B, DeLarco J E, et al. Increased secretion of type beta transformation growth factor accompanies viral transformation. Mol Cell Biol. 1985; 5: 242–247
  • Roberts A B, Sporn M B. Physiological actions and clinical applications of transforming growth factor-β (TGF-β). Growth Factors. 1993; 8: 1–9
  • Raghow R, Postlethwait A E, Keski-Oja J, Moses H L, Kang A H. Transforming growth factor-β increases steady state levels of type I collagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts. J Clin Invest. 1987; 79: 1285–1288
  • Ignotz R A, Massague J. Cell adhesion protein receptors as targets for transforming growth factor-β action. Cell. 1987; 51: 189–197
  • Sato Y, Tsuboi R, Lyons R, Moses H, Rifkin D B. Characterization of the activation of latent TGF-β by co-cultures of endothelial cells, and pericytes and smooth muscle cells: a self-regulating system. J. Cell Biol. 1990; 111: 757–763
  • Jennings M T, Maciunas R J, Carver R, et al. TGF β1 and TGF β2 are potent growth regulators for low grade and malignant gliomas in vitro:evidence in support of an autocrine hypothesis. Int J Cancer. 1991; 49: 129–139
  • Haddow S, Fowlis D J, Parkinson K, Akhurst R J, Balmain A. Loss of growth control by TGF-β occurs at a late stage of mouse skin carcinogenesis and is independent of ras gene inactivation. Oncogene. 1991; 6: 165–170
  • Massague J, Attisano L, Wranna J. The TGF-β family and its composite receptors. Trends Cell Biol. 1994; 4: 172–178
  • Markowitz S, Wang J, Myerhoff L, et al. Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science 1995; 268: 1336–1338
  • Myerhoff L L, Parsons R, Kim S -J, et al. A transforming growth factor β receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability. Cancer Res. 1995; 55: 5545–5547
  • Parsons R, Myerhoff L L, Liu B, et al. Microsatellite instability and mutations of the TGF-β type II receptor gene in colorectal cancer. Cancer Res. 1995; 55: 5548–5550
  • Garrigue-Antar L, Munoz-Antonia T, Antonia S, Gesmonde J, Vellucci V, Reiss M. Mis-sense mutations of the transforming growth factor β type II receptor in head and neck squamous carcinoma cells. Cancer Res. 1995; 55: 3982–3987
  • Baldwin R L, Friess H, Yokoyama M, et al. Attenuated ALK5 receptor expression in human pancreatic cancer: correlation with resistance to growth inhibition. Int J Cancer. 1996; 67: 283–288
  • DeCoteau J F, Knaus P I, Yankelev H, et al. Loss of functional cell surface transforming growth factor β (TGF-β) type I receptor correlates with insensitivity to TGF-β in chronic lymphocytic leukemia. Proc. Natl Acad Sci USA. 1997; 94: 5877–5881

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