Lipoxygenase Inhibitors Prevent Lung Carcinogenesis and Inhibit Non-Small Cell Lung Cancer Growth

References

• Moody T W, Cuttitta F. Growth factors and receptors in lung cancer. Life Sci. 1993; 52: 1161–1173
   PubMed Web of Science ®Google Scholar
• Moody T W. Peptides and growth factors in non-small cell lung cancer. Peptides. 1996; 17: 545–555
   PubMed Web of Science ®Google Scholar
• Moody T W, Murphy A, Mahmoud S, Fiskum G. Bombesin-like peptides elevate cytosolic calcium in small cell lung cancer cells. Biochem Biophys Res Commun. 1987; 147: 189–195
   PubMed Web of Science ®Google Scholar
• Trepel J, Moyer J, Cuttitta F, et al. A novel bombesin receptor antagonist inhibits autocrine signals in a small cell lung carcinoma cell line. Biochem Biophys Res Commun 1988; 156: 1383–1389
   PubMed Web of Science ®Google Scholar
• Nakanishi Y, Mulshine J, Kasprzyk P, et al. Insulin-like growth factor-1 can stimulate the proliferation of human small cell lung cancer lines. J Clin Invest. 1988; 82: 354–359
   PubMed Web of Science ®Google Scholar
• Zia F, Jacobs S, Kull F, Jr, Cuttitta F, Mulshine J, Moody T W. Monoclonal antibody αIR-3 inhibits non-small cell lung cancer growth in vitro and in vivo. J Cell Biochem. 1996; 24s: 269–275
   Google Scholar
• Rechler M W, Nissley S P. The nature and regulation of the receptor for insulin-like growth factors. Annu Rev Physiol. 1994; 47: 425–442
   Google Scholar
• Moody T W, Zia F, Venugopal R, Fagarasan M, Oie H, Hu V. GRP receptors are present on non-small cell lung cancer cell lines. J Cell Biochem. 1996; 24s: 247–256
   Google Scholar
• Millar J, Rozengurt E. Arachidonic acid release by bombesin. J Biol Chem. 1990; 265: 19973–19979
   PubMed Web of Science ®Google Scholar
• Dewitt D L. Prostaglandin endoperoxide synthase: regulation of enzyme expression. Biochim Biophys Acta. 1991; 1083: 121–134
   PubMed Web of Science ®Google Scholar
• Hubbard W C, Alley M C, Gray G N, Green K C, McLemore T L, Boyd M R. Evidence for prostanoid biosynthesis as a biochemical feature of certain subclasses of non-small cell carcinomas of the lung as determined in established cell lines derived from human lung tumors. Cancer Res. 1989; 49: 826–832
   PubMed Web of Science ®Google Scholar
• Duperron C, Castonguay A. Inhibition of lung tunorigenesis by aspirin in A/J mice. Cancer Res Proc. 1996; 36: 592
   Google Scholar
• Samuelsson B, Dahlen S E, Lindren J A, Rouzer C A, Serhan C N. Leukotrienes and lipoxins: structures, biosynthesis and biological effects. Science 1987; 237: 1171–1176
   PubMed Web of Science ®Google Scholar
• Avis I M, Jett M, Boyle T, et al. Growth control of lung cancer by interruption of 5-lipoxygenase-mediated growth factor signalling. J Clin Invest. 1996; 97: 806–813
   PubMed Web of Science ®Google Scholar
• Carney D N, Gazdar A F, Bepler G, et al. Establishment and identification of small cell lung cancer cell lines having classic and variant features. Cancer Res. 1985; 45: 2913–2923
   PubMed Web of Science ®Google Scholar
• Chirgwin J M, Przybyla A E, MacDonald R J, Rutter W J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 1979; 18: 5294–5299
   PubMed Web of Science ®Google Scholar
• Davis L, Dibner M, Battey J F. Basic Methods in Molecular Biology. Elsevier, New York 1986
   Google Scholar
• Mahmoud S, Staley J, Taylor J, et al. (Psi13,14) Bombesin analogues inhibit the growth of small cell lung cancer in vitro and in vivo. Cancer Res. 1991; 51: 1798–1802
   PubMed Web of Science ®Google Scholar
• Malkinson A M. Primary lung tumors in mice: an experimentally manipulable model of human adenocarcinoma. Cancer Res. 1992; 52: 2670s–2676s
   PubMed Web of Science ®Google Scholar
• Dixon R AF, Diehl R E, Opas E, et al. Requirement of a 5-lipoxygenase-activating protein for leuko-triene synthesis. Nature 1990; 343: 282–284
   PubMed Web of Science ®Google Scholar
• Matsumoto T, Funk C D, Radmark O, Hoog J O, Jornvall H, Samuelsson B. Molecular cloning and amino acid sequence of human 5-lipoxygenase. Proc Natl Acad Sci USA. 1988; 85: 26–30
   PubMed Web of Science ®Google Scholar
• Rouzer C A, Ford-Hutchinson A W, Morton H, Gillard J. MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes. J Biol Chem. 1990; 265: 1436–1442
   PubMed Web of Science ®Google Scholar
• Rozengurt E, Sinett-Smith J. Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cells. Proc Natl Acad Sci USA. 1993; 80: 2936–2940
   Google Scholar
• Marquez C, Treston A, You L, et al. Chemoprevention of lung adenomas by BW2258U89. Cancer Res Proc. 1996; 37: 270
   Google Scholar
• Lee M, Draoui M, Zia F, et al. Epidermal growth factor receptor monoclonal antibodies inhibit the growth of lung cancer cell lines. JNCI Monogr. 1992; 13: 117–123
   Google Scholar
• Moody T W, Zia F, Draoui M, et al. A novel VIP antagonist inhibits non-small cell lung cancer growth. Proc Natl Acad Sci USA. 1993; 90: 4345–4349
   PubMed Web of Science ®Google Scholar
• Rioux N, Castonguay A. A new class of cancer chemopreventive agents: 5-lipoxygenase inhibitors. Cancer Res Proc. 1997; 38: 262
   Google Scholar
• Hubbard W C, Litterist C L, Liu M C, et al. Profiling of prostaglandin biosynthesis in biopsy fragments of human lung carcinomas and normal human lung by capillary gas chromatography-negative ion chemical ionization mass spectrometry. Prostaglandins. 1986; 32: 889–906
   PubMedGoogle Scholar
• Moody T W, Hida T, Mulshine J, et al. Cyclooxygenase inhibitors reduce prostaglandin E2 and the growth of non-small cell lung cancer cells. Cancer Res Proc. 1995; 36: 601
   Google Scholar