An Image Analysis Workstation Designed for Multiple Users: Application of Quantitative Digital Imaging Techniques to Electron Microscopy

References

• Hall T L, Fu Y S. Applications of quantitative microscopy in tumor pathology. Lab Invest. 1985; 53: 5–21
   PubMedGoogle Scholar
• Marchevsky A M, Gil J. Applications of computerized interactive morphometry in pathology. II. A model for computer generated diagnosis. Lab Invest. 1986; 54: 708–716
   PubMedGoogle Scholar
• Baak J PA. The principles and advances of quantitative pathology. Anal Quant Cytol His-tol. 1987; 9: 89–95
   PubMed Web of Science ®Google Scholar
• Collan Y, Torkkeli T, Pesonen E, Jantunen E, Kosma V-M. Application of morphometry in tumor pathology. Anal Quant Cytol Histol. 1987; 9: 79–88
   PubMedGoogle Scholar
• Loud A V. Electron microscopic morphometry. Anal Quant Cytol Histol. 1987; 9: 7–12
   PubMedGoogle Scholar
• Pesce C M. Defining and interpreting diseases through morphometry. Lab Invest. 1987; 56: 568–575
   PubMedGoogle Scholar
• Payne C M, Ray C G, Yolken R H. The 30- to 54-nm rotavirus-like particles in gastroenteritis: incidence and antigenic relationship to rotavirus. J Med Virol. 1981; 7: 299–313
   PubMedGoogle Scholar
• Payne C M, Ray C G, Borduin V, Minnich L L, Lebowitz M D. An eight-year study of the viral agents of acute gastroenteritis in humans: ultrastructural observations and seasonal distribution with a major emphasis on coronavirus-like particles. Diagn Microbiol Infect Dis. 1986; 5: 39–54
   PubMed Web of Science ®Google Scholar
• Payne C M, Nagle R B, Borduin V. An ultrastructural cytochemical stain specific for neuroendocrine neoplasms. Lab Invest. 1984; 51: 350–365
   PubMed Web of Science ®Google Scholar
• Payne C M, Nagle R B, Paplanus S H, Graham A R. Fibrolamellar carcinoma of liver: a primary malignant oncocytic carcinoid. Ultrastruct Pathol. 1986; 10: 539–552
   PubMed Web of Science ®Google Scholar
• Payne C M, Cromey D W. Ultrastructural similarities between Chlorohydra viridissima and human neurosecretory granules: a cytochemical study using the uranaffin reaction. Cytobios. 1987; 50: 191–203
   PubMedGoogle Scholar
• Payne C M, Stern L Z, Curless R G, Hannapel L K. Ultrastructural fiber typing in normal and diseased human muscle. J Neurol Sci. 1975; 25: 99–108
   PubMedGoogle Scholar
• Payne C M, Curless R G. Concentric laminated bodies. Ultrastructural demonstration of muscle fiber type specificity. J Neurol Sci. 1976; 29: 311–322
   PubMedGoogle Scholar
• Payne C M, Curless R G. Fingerprint inclusions. Ultrastructural demonstration of muscle fiber type specificity. J Neurol Sci. 1977; 31: 379–386
   PubMedGoogle Scholar
• Payne C M, Nagle R B, Lynch P J. Quantitative electron microscopy in the diagnosis of mycosis fungoides. A simple analysis of lymphocytic nuclear convolutions. Arch Dermatol. 1984; 120: 63–75
   PubMed Web of Science ®Google Scholar
• Payne C M, Grogan T M, Lynch P J. An ultrastructural morphometric and immunohisto-chemical analysis of cutaneous lymphomas and benign lymphocytic infiltrates of skin. Useful criteria for diagnosis. Arch Dermatol. 1986; 122: 1139–1154
   PubMedGoogle Scholar
• Payne C M, Glasser L. Ultrastructural morphometry in the diagnosis of Sézary syndrome. Arch Pathol Lab Med 1990; 114: 661–671
   PubMedGoogle Scholar
• Payne C M, Glasser L. An ultrastructural morphometric analysis of platelet giant and fusion granules. Blood. 1986; 67: 299–309
   PubMedGoogle Scholar
• Payne C M. Quantitative electron microscopy and ultrastructural cytochemistry in the diagnosis of hematologic disorders. J Med Technol. 1984; 1: 206–215
   Google Scholar
• Arndt-Jovin D J, Robert-Nicoud M, Kaufman S J, Jovin T M. Fluorescence digital imaging microscopy in cell biology. Science 1985; 230: 247–256
   PubMed Web of Science ®Google Scholar
• Tsunoda Y, Todozawa S, Tashiro Y. Heterogeneous distribution of free calcium and propagation of calcium transient in gastric parietal cells revealed by digital imaging microscopy. J Histochem Cytochem. 1989; 37: 999–1005
   PubMed Web of Science ®Google Scholar
• McEachron D L. Image processing for the rest of us: the potential utility of inexpensive computerized image analysis in clinical pathology and radiology. Comput Med Imaging Graphics 1989; 13: 3–30
   PubMed Web of Science ®Google Scholar
• Silage D A, Gil J. Digital reversal and enhancement of negatives in video-based interactive morphometry. Lab Invest. 1984; 51: 112–116
   PubMedGoogle Scholar
• Bartels P H, Wied G L. Automated image analysis in clinical pathology. Am J Clin Pathol. 1981; 75: 489–493
   PubMedGoogle Scholar
• Bartels P H, Olson G B, Lockart R, Wied G L. Cytophotometric studies of cell populations. Cell Biophys. 1980; 2: 339–351
   PubMedGoogle Scholar
• Russell J H, Masakowski V R, Dobos C B. Mechanisms of immune lysis. I. Physiological distinction between target cell death mediated by cytotoxic T lymphocytes and antibody plus complement. J Immunol. 1980; 124: 1100–1105
   PubMedGoogle Scholar
• Wyllie A H. Cell death: A new classification separating apoptosis from necrosis. Cell Death in Biology and Pathology, I D Bowen, R A Lockshin. Chapman and Hall, New York 1981; 9–34
   Google Scholar
• Searle J, Kerr J FR, Bishop C J. Necrosis and apoptosis: distinct modes of cell death with fundamentally different significance. Pathol Annu. 1982; 17: 229–259
   PubMed Web of Science ®Google Scholar
• Bishop C J, Rzepczyk C M, Stenzel D, Anderson K. The role of reactive oxygen metabolites in lymphocyte-mediated cytolysis. J Cell Sci. 1987; 87: 473–481
   PubMedGoogle Scholar
• Walker N I, Harmon B V, Gobe G C, Kerr J FR. Patterns of cell death. Method Achiev Exp Pathol. 1988; 13: 18–54
   PubMedGoogle Scholar
• Afanasev V N, Korol' B A, Mantsygin Y A, Neli-Povich P A, Pechatnikov V A, Umansky S R. Flow cytometry and biochemical analysis of DNA degradation characteristic of two types of cell death. FEBS Lett. 1986; 194: 347–350
   PubMed Web of Science ®Google Scholar
• Duvall E, Wyllie A H. Death and the cell. Immunol Today. 1986; 7: 115–119
   PubMedGoogle Scholar
• Kerr J FR. Shrinkage necrosis: a distinct mode of cellular death. J Pathol. 1971; 105: 13–20
   PubMed Web of Science ®Google Scholar
• Cooper E H, Bedford A J, Kenny T E. Cell death in normal and malignant tissues. Adv Cancer Res. 1975; 21: 59–120
   PubMedGoogle Scholar
• Wyllie A H, Kerr J FR, Currie A R. Cell death: the significance of apoptosis. Int Rev Cytol. 1980; 68: 251–306
   PubMedGoogle Scholar
• Lockshin R A, Beaulaton J. Cell death: questions for histochemists concerning the causes of the various cytological changes. Histochem J. 1981; 13: 659–666
   PubMedGoogle Scholar
• Wyllie A H, Beattie G J, Hargreaves A D. Chromatin changes in apoptosis. Histochem J. 1981; 13: 681–692
   PubMedGoogle Scholar
• Wyllie A H, Morris R G, Smith A L, Dunlop D. Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis. J Pathol. 1984; 142: 67–77
   PubMed Web of Science ®Google Scholar
• Ucker D S. Cytotoxic T lymphocytes and glucocorticoids activate an endogenous suicide process in target cells. Nature (London). 1987; 327: 62–64
   PubMed Web of Science ®Google Scholar
• McConkey D J, Nicotera P, Hartzell P, Bellomo G, Wyllie A H, Orrenius S. Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration. Arch Biochem Biophys. 1989; 269: 365–370
   PubMed Web of Science ®Google Scholar
• Wyllie A H. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous en-donuclease activation. Nature (London). 1980; 284: 555–556
   PubMed Web of Science ®Google Scholar
• Duke R C, Chervenak R, Cohen J J. Endoge-neous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis. Proc Natl Acad Sci USA 1983; 80: 6361–6365
   PubMed Web of Science ®Google Scholar
• Cohen J J, Duke R C. Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. J Immunol. 1984; 132: 38–42
   PubMed Web of Science ®Google Scholar
• McConkey D J, Hartzell P, Duddy S K, Hakans-Son H., Orrenius S. 2,3,7,8-Tetrachlorodibenzo-p-dioxin kills immature thymocytes by Ca2+ -mediated endonuclease activation. Science 1988; 242: 256–259
   PubMed Web of Science ®Google Scholar
• Yamada T, Ohyama H. Radiation-induced interphase death of rat thymocytes is internally programmed (apoptosis). Int J Radiat Biol. 1988; 53: 65–75
   Web of Science ®Google Scholar
• Duke R C, Cohen J J. The role of nuclear damage in lysis of target cells by cytotoxic T lymphocytes. Cytolytic Lymphocytes and Complement: Effectors of the Immune System, E R Podack. CRC Press, Boca Raton, FL 1988; Volume II: 35–57
   Google Scholar