396
Views
58
CrossRef citations to date
0
Altmetric
Original Article

Alginate encapsulation of genetically engineered mammalian cells: Comparison of production devices, methods and microcapsule characteristics

, , , &
Pages 303-316 | Received 15 May 2002, Accepted 07 Oct 2002, Published online: 02 Jul 2010

References

  • Berens M. E., Giese A., Shapiro J. R., Coons S. W. Allogeneic astrocytoma in immune competent dogs. Neoplasia 1999; 1: 107–112
  • Chang T. M., Prakash S. Therapeutic uses of microencapsulated genetically engineered cells. Molecular Medicine Today 1998; 4: 221–227
  • De Vos P., De Haan B., Pater J., Van Schilfgaarde R. Association between capsule diameter, adequacy of encapsulation, and survival of microencapsulated rat islet allografts. Transplantation 1996; 62: 893–899
  • Gaumann A., Laudes M., Jacob B., Pommersheim R., Laue C., Vogt W., Schrezenmeir J. Xenotransplantation of parathyroids in rats using bariumalginate and polyacrylic acid multilayer microcapsules. Experimental and Toxicologic Pathology 2001; 53: 35–43
  • Geng Y. J., Wu Q., Muszynski M., Hansson G. K., Libby P. Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with interferon-γ, tumour necrosis factor-α, and interleucin-1β. Arteriosclerosis, Thrombosis, and Vascular Biology 1996; 16: 19–27
  • Ghosal S. K., Talukdar P., Pal T. K. Standarddization of a newly designed vibration capillary apparatus for the preparation of microcapsules. Chemical Engineering and Technology 1993; 16: 395–398
  • Joki T., Machluf M., Atala A., Zhu J., Seyfried N. T., Dunn I. F., Abe T., Carroll R. S., Black P. M. Continuous release of endostatin from microencapsulated engineered cells for tumour therapy. Nature Biotechnology 2001; 19: 35–39
  • Klock G., Pfeermann A., Ryser C., Grohn P., Kuttler B., Hahn H. J., Zimmermann U. Biocompatibility of mannuronic acid-rich alginates. Biomaterials 1997; 18: 707–713
  • Kulseng B., Skjak-Braek G., Ryan L., Andersson A., King A., Faxvaag A., Espevik T. Transplantation of alginate microcapsules: generation of antibodies against alginates and encapsulated porcine islet-like cell clusters. Transplantation 1999; 67: 978–984
  • Lim F., Sun A. M. Microencapsulated islets as a bioartificial pancreas. Science 1980; 210: 908–910
  • Lohr M., Hoffmeyer A., Kroger J., Freund M., Hain J., Holle A., Karle P., Knofel W. T., Liebe S., Muller P., Nizze H., Renner M., Saller R. M., Wagner T., Hauenstein K., Gunzburg W. H., Salmons B. Microencapsulated cell-mediated treatment of inoperable pancreatic carcinoma. Lancet 2001; 357: 1591–1592
  • Peirone M., Ross C. J., Hortelano G., Brash J. L., Chang P. L. Encapsulation of various recombinant mammalian cell types in different alginate microcapsules. Journal of Biomedical Materials Research 1998; 42: 587–596
  • Rainov N. G., Zimmer C., Chase M., Kramm C. M., Chiocca E. A., Weissleder R., Breakefield X. O. Selektive uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms. Human Gene Therapy 1995; 6: 1543–1552
  • Ram Z., Culver K. W., Oshiro E. M., Viola J. J., De Vroom H. L., Otto E., Long Z., Chiang Y., McGarrity G. J., Muul L. M., Katz D., Blaese R. M., Oldfield E. H. Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nature Medicine 1997; 3: 1354–1361
  • Rigler R. Acridine orange in nucleic acid analysis. Annals of the New York Acadamy of Sciences 1969; 157: 211–224
  • Robttaille R., Pariseau J. F., Leblond F. A., Lamoureux M., Lepage Y., Halle J. P. Studies on small (<350μm) alginate-poly-L-lysine microcapsules. III. Biocompatibility of smaller versus standard microcapsules. Journal of Biomedical Materials Research 1999; 44: 116–120
  • Sakai S., Ono T., Ijima H., Kawakami K. Control of molecular weight cut-off for immunoisolation by multilayering glycol chitosan-alginate polyion complex on alginate-based microcapsules. Journal of Microencapsulation 2000; 17: 691–699
  • Schwinger C., Koch S., Jahnz U., Wittlich P., Rainov N. G., Kressler J. High throughput encapsulation of mouse fibroblasts in alginate using the JetCutter technology. Journal of Microencapsulation 2002; 19: 273–280
  • Seifert D. B., Phillips J. A. Production of small, monodispersed alginate beads for cell immobilization. Biotechnology Progress 1997; 13: 562–568
  • Serp D., Catana E., Heinzen C., von Stockar U., Marison I. W. Characterization of an encapsulation device for the production of monodisperse alginate beads for cell immobilization. Biotechnology and Bioengineering 2000; 70: 41–53
  • Shimi S. M., Newman E. L., Hopwood D., Cushieri A. Semi-permeable microcapsules for cell culture: ultra-structural characterization. Journal of Microencapsulation 1991; 8: 307–316
  • Thu B., Bruheim P., Espevik T., Smidsrod O., Soon-Shiong P., Skjak-Braek G. Alginate polycation microcapsules. I. Interaction between alginate and polycation. Biomaterials 1996a; 17: 1031–1040
  • Thu B., Bruheim P., Espevik T., Smidsrod O., Soon-Shiong P., Skjak-Braek G. Alginate polycation microcapsules. II. Some functional properties. Biomaterials 1996b; 17: 1069–1079
  • Uludag H., De Vos P., Tresco P. A. Technology of mammalian cell encapsulation. Advanced Drug Delivery Reviews 2000; 42: 29–64
  • Vallbacka J. J., Nobrega J. N., Sefton M. V. Tissue engineering as a platform for controlled release of therapeutic agents: implantation of microencapsulated dopamine producing cells in the brains of rats. Journal of Controlled Release 2001; 72: 93–100
  • Xue Y., Gao J., Xi Z., Wang Z., Li X., Cui X., Luo Y., Li C., Wang L., Zhou D., Sun R., Sun A. M. Microencapsulated bovine chromaffin cell xenografts into hemiparkinsonian rats: a drug-induced rotational behavior and histological changes analysis. Artificial Organs 2001; 25: 131–135
  • Zurn A. D., Baetge E. E., Hammang J. P., Tan S. A., Aebischer P. Glial cell line-derived neurotrophic factor (GDNF), a new neurotrophic factor for motoneurones. NeuroReport 1994; 6: 113–118

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.