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Journal of Microencapsulation
Micro and Nano Carriers
Volume 20, 2003 - Issue 3
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Original Article

Formation of alginate microspheres produced using emulsification technique

P. W. S. Heng Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore, 117543Correspondence[email protected]
,
L. W. Chan Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore, 117543
&
T. W. Wong Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore, 117543
Pages 401-413 | Received 08 Jul 2002, Accepted 20 Jan 2003, Published online: 02 Jul 2010

References

  • Chan L. W., Heng P. W. S., Wan L. S. C. Effect of cellulose derivatives on alginate microspheres prepared by emulsification. Journal of Microencapsulation 1997; 14: 545–555
  • Cussler E. L. Diffusion: mass transfer in fluid systems. Cambridge University Press, Cambridge 1997
  • Fundueanu G., Esposito E., Mihai D., Carpor A., Desbrieres J., Rinaudo M., Nastruzzi C. Preparation and characterization of Ca-alginate microspheres by a new emulsification method. International Journal of Pharmaceutics 1998; 170: 11–21
  • Gombotz W. R., Wee S. F. Protein release from alginate matrices. Advanced Drug Delivery Reviews 1998; 31: 267–285
  • Thu B., Skjak-Br/ek G., Micali F., Vittur F., Rizzo R. The spatial distribution of calcium in alginate gel beads analysed by synchroton-radiation induced X-ray emission (SRIXE). Carbohydrate Research 1997; 297: 101–105
  • Wan L. S. C., Heng P. W. S., Chan L. W. Influence of hydrophile-lipophile balance on alginate microspheres. International Journal of Pharmaceutics 1993; 95: 77–83
  • Wan L. S. C., Heng P. W. S., Chan L. W. Surfactant effects on alginate microspheres. International Journal of Pharmaceutics 1994; 103: 267–275
  • Wang X., Spencer H. G. Calcium alginate gels: formation and stability in the presence of inert electrolyte. Polymer 1998; 139: 2759–2764
  • Wong T. W., Lee H. Y., Chan L. W., Heng P. W. S. Release characteristics of pectinate microspheres prepared by an emulsification technique. Journal of Microencapsulation 2002; 19: 511–522
  • Wong T. W., Wan L. S. C., Heng P. W. S. Effects of physical properties of PEG 6000 on pellets produced by melt pelletization. Pharmaceutical Development and Technology 1999; 4: 449–456

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