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Original Article

Oxprenolol-loaded bioadhesive microspheres: Preparation and in vitro/in vivo characterization

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Pages 777-789 | Received 17 Feb 2003, Accepted 20 Jun 2003, Published online: 02 Jul 2010

References

  • Akijama Y., Nagahara N., Nara E., Kitano M., Iwasa S., Yamamoto J., Ogawa Y. Evaluation of oral mucoadhesive microspheres in man on the basis of the pharmacokinetics of furosemide and riboflavin, compounds with limited gastrointestinal absorption site. Journal of Pharmaceutics and Pharmacology 1988; 50: 159–166
  • Ching H. S., Park H., Kelly P., Robinson J. R. Bioadhesive polymers as platforms for oral controlled drug delivery. II. Synthesis and evaluation of some swelling water insoluble bioadhesive polymers. Journal of Pharmaceutical Sciences 1985; 74: 399–405
  • Chemtob C., Assimacopoulos T., Chaumeil J. C. Preparation and characteristics of gelatin microspheres. Drug Development and Industrial Pharmacology 1993; 14: 1359–1374
  • Duchene D., Touchard F., Peppas N. A. Pharmaceutical and medical aspects of bioadhesive systems for drug administration. Drug Development and Industrial Pharmacy 1988; 14: 283–318
  • Gibaldi M., Perrier D. Pharmacokinetics. M. Dekker, New York 1975
  • Goto S., Komatso M., Tagawa K., Kawata M. Preparation and evaluation of gelatin microcapsules of sulfonamides. Chemical and Pharmacological Bulletin (Tokyo) 1993; 31: 256–318
  • Jimenez-Castellanos M. R., Zia H., Rhodes C. T. Mucoadhesive drug delivery systems. Drug Development and Industrial Pharmacology 1993; 19: 143–194
  • Leucuta S. E., Ponchel G., Duchene D. Dynamic swelling behaviour of gelatin/poly (acrylic acid) bioadhesive microspheres loaded with oxprenolol. Journal of Microencapsulation 1997a; 14: 501–510
  • Leucuta S. E., Ponchel G., Duchene D. Oxprenolol release from bioadhesive gelatin/poly(acrylic acid) microspheres. Journal of Microencapsulation 1997b; 14: 511–522
  • Leucuta S. E., Pop R. D. Farmacocinetica. Dacia, Cluj-Napoca 1981
  • Peppas N. A., Sahlin J. J. A simple equation for the description of solute release. III. Coupling of diffusion and relaxation. International Journal of Pharmacology 1989; 57: 169–172
  • Preda M., Leucuta S. E., Ponchel G., Duchene D. Preparation and characterization of oxprenolol loaded bioadhesive microspheres. Proceedings of the 13th Pharmaceutical Technology Conference, Strasbourg. Solid Dosage Research Unit, Liverpool 1994; vol. 1: 379–391
  • Ranga K. Rao V., Buri P. A novel in situ method to test polymers and coated microparticles for bioadhesion. International Journal of Pharmacology 1989; 52: 265–270
  • Sioufi A., Colusssi D., Mangoni P. Gas chromatographic determination of oxprenolol in human plasma. Journal of Chromatography 1983; 278: 185–188
  • Vandelli M. A., Forni F., Coppi G., Cameroni R. The effect of the cross-linked time period upon the drug release and the dynamic swelling of gelatin microspheres. Pharmazie 1991; 46: 866–869

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