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Original Article

Synthesis and release studies of shikonin-containing microcapsules prepared by the solvent evaporation method

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Pages 581-596 | Received 17 Sep 2002, Accepted 20 Feb 2003, Published online: 02 Jul 2010

References

  • Arshady R. Microspheres, Microcapsules and Liposomes. Citus Books, London 1999; Vol. 1
  • Bakan J., Anderson J. L. Microencapsulation. The theory and practice of industrial Pharmacy, L. Lachman, H. Lieberman, J. Kanig. Lea & Fobiger, Philadelphia 1986; 412
  • Chen F. A., Cheng H. W., Wu A. B., Hsu H. C., Chen C. Y. Kinetic studies of the photochemical decomposition of alkannin/shikonin enantiomers. Chemical Pharmaceutical Bulletin 1996; 44: 249–251
  • Cheng H. W., Chen F. A., Hsu H. C., Chen C. Y. Photochemical decomposition of alkannin/shikonin enantiomers. International Journal of Pharmaceutics 1995; 120: 137–144
  • Deasy P. B. Microencapsulation and Related Drug Processes. Marcel Dekker Inc., New York 1984
  • Driscoll J. S., Hazard G. F., Wood H. B., Goldin A. Structure-antitumor activity relationships among quinone derivatives. Cancer Chemotherapy Reports, Part 2 1974; 4: 1–362
  • Gabr K. E. Influence of indomethacin-mastic combinations on dissolution, absorption and gastrointestinal mucosal damage in rats. International Journal of Pharmaceutics 1997; 158: 137–145
  • Guo X. P., Zhang X. Y., Zhang S. D. Clinical trial on the effect of shikonin mixture on later stage lung cancer. Chung His I Chieh Ho Tsa Chih, Zhong Xi Yi Jie He Za Zhi 1991; 11: 598–599
  • Hashimoto S., Hu M., Masuda Y., Aiuchi T., Nakajo S., Cao J., Miyakoshi M., Ida Y., Nakaya K. Beta-hydroxyisovalerylshikonin inhibits the cell growth of various cancer cell lines and induces apoptosis in leukemia HL-60 cells through a mechanism different from those of Fas and etoposide. Journal of Biochemistry 1999; 125: 17–23
  • Hayashi M. Pharmacological studies on crude plant drugs, Shikon and Tooki. II: shikonin and acetylshikonin. Nippon Yakurigaku Zasshi 1977a; 73: 193–203, (C.A.: 88, 44863e, 1978)
  • Hayashi M. Pharmacological studies on crude plant drugs, Shikon and Tooki. III: effect of topical application of ether extracts and Shiunko on inflammatory reaction. Nippon Yakurigaku Zasshi 1977b; 73: 205–214, (C.A: 88, 44864f, 1978)
  • Hayashi M. Pharmacological studies on crude plant drugs, Shikon and Tooki (I): ether and water extracts. Nippon Yakurigaku Zasshi 1977c; 73: 177–191, (C.A: 88, 44862d, 1978)
  • Jones D. S., Pearce K. J. Contribution of process variables to the entrapment efficiency of propranolol hydrochloride within ethylcellulose microspheres prepared by the solvent evaporation method as evaluated using a factorial design. International Journal of Pharmaceutics 1996; 131: 25–31
  • Kielbania J., Andrew J., Emmons W., Redlich G. Process for microencapsulation. US Patent #5,277,979, 01/94
  • Liu M., Ohuchi T., Ieiri T., Ohe M., Matsuzaki S. Shikonin has potent antibacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA). Dokkyo Journal of Medical Sciences 1996; 23: 63–69
  • Lu G., Liao J. Detection of the anti-cancer biological effect of naphthoquinone pigment-LIII. Chung His I Chieh Ho Tsa Chih, Zhong Xi Yi Jie He Za Zhi 1990; 10: 422–425
  • Mandal T., Tenjarla S. Preparation of biodegradable microcapsules of zidovudine using solvent evaporation: effect of the modification of aqueous phase. International Journal of Pharmaceutics 1996; 137: 187–197
  • Morrison D., Mosier B. Microcapsules and methods for making. US Patent #5,827,531, 1998, 10/1998
  • Nixon J. R. Preparation of microcapsules with possible pharmaceutical use. Endeavour New Series 1985; 9: 123–128
  • O'Donnell P. B., McGinity J. W. Preparation of microspheres by the solvent evaporation technique. Advanced Drug Delivery Reviews 1997; 28: 25–42
  • Papageorgiou V. P. Wound healing properties of naphthaquinone pigments from Alkanna tinctoria. Experientia 1978a; 34: 1499–1500
  • Papageorgiou V. P., Patent #DE-B 2700448, 1978b
  • Papageorgiou V. P., Patent #DE-B 2829 744, 1979
  • Papageorgiou V. P. Naturally occurring isohexenylnaphthazarin pigments: a new class of drugs. Planta Medica 1980; 38: 193–203
  • Papageorgiou V. P., Patent #US-A 4282250, 1981
  • Papageorgiou V. P., Assimopoulou A. N., Couladouros E. A., Hepworth D., Nicolaou K. C. Chemistry and biology of alkannins, shikonins and related naphthazarin natural products. Angewandte Chemie, International Edition 1999; 38: 5000–5029
  • Papageorgiou V. P., Assimopoulou A. N., Kyriacou G. Determination of naturally occurring hydroxynaphthoquinone polymers by size exclusion chromatography. Chromatographia 2002; 55: 423–430
  • Papageorgiou V. P., Mellidis A. S., Assimopoulou A. N. Polymerization of isohexenylnaphthazarin pigments, a new class of drugs. Proceedings of the 1st Panhellenic Conference of Chemical Engineering, PatrasGreece, 1997; 277–282
  • Papageorgiou V. P., Mellidis A. S., Sagredos A. N. Study on the antibiotic fraction of Alkanna tinctoria Tausch. Chimica Chronicles New Series 1980; 9: 57–63
  • Perng C. Y., Kearney A. S., Patel K., Palepu N. R., Zuber G. Investigation of formulation approaches to improve the dissolution of SB-210661, a poorly water soluble 5-lipoxygenase inhibitor. International Journal of Pharmaceutics 1998; 176: 31–38
  • Sekine T., Kojima K., Sasaki S., Matsumoto T., Yamamoto T., Maitani Y., Nagai T. Evaluation of antibacterial effect of shikonin ointment against methicillin-resistant Staphylococcus aureus. STP Pharma Sciences 1998; 8: 255–259
  • Yoon Y., Kim Y. O., Lim N. Y., Jeon W. K., Sung H. J. Shikonin, an ingredient of Lithospermum erythrorhizon induced apoptosis in HL60 human premyelocytic Leukemia cell line. Planta Medica 1999; 65: 532–535

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