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Research Article

Preparation and evaluation of fast-release mephenamic acid microspheres

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Pages 640-656 | Received 23 Mar 2010, Accepted 22 Jun 2010, Published online: 03 Aug 2010

References

  • Adeyeye CM, Price JC. Development and evaluation of sustained release Ibuprofen-wax Microspheres. I. Effect of formulation variables on physical characteristics. Pharm. Res 1991; 8: 1377–83
  • Ahmed SM, Saleh SI, Aboutaleb AE. Evaluation of tableted cinnarizine microcrystalline cellulose ground mixture. Bull Pharm Sci Assiut Univ 1992; 15: 57–62
  • Akbuga JJ. Effect of microsphere size and formulation factors on drug release from controlled release furosemide microspheres. Drug Dev Ind Pharm 1991; 17: 593–607
  • Akbuga J, Gulhan S, Bayraktar G. Studies of flufenamic acid capsules and tablets. Pharmazie 1983; 38: 478–80
  • Aulton ME. Pharmaceutics: The science of dosage forms design. Longman group, Hong Kong 1988; 282–99
  • Benita S, Zouai O, Benoit JP. 5- Flurouracil: Carnauba wax microspheres for chemoembilization: An in-vitro evaluation. J Pharm Sci 1986; 75: 847–51
  • Betageri GV, Makarla KR. Enhancement of dissolution of glyburide by solid dispersion and lyophillization techniques. Int J Pharm 1995; 126: 155–60
  • Bouillot P, Ubrich N, Sommer F, Duc TM, Loeffler JP, Dellacherie E. Protein encapsulation in biodegradable amphiphilic microspheres. Int J Pharm 1999; 181: 159–72
  • Budavari S. The Merck Index: An encyclopedia of chemicals, drugs and biological, 13th ed. Merck Research Laboratories Division of Merck & Co., Whitehouse Station, NJ 2001, Inc., p. 1493
  • Chang RK, Price JC, Whitworth CW. Control of drug release rate by use of mixtures of polycaprolactone and cellulose acetate butyrate. Drug Dev Ind Pharm 1987; 13: 1119–35
  • Chiou WL, Riegelman S. Pharmaceutical applications of solid dispersion systems. J Pharm Sci 1971; 60: 1281–302
  • Choudhari KB, Sanghavi NM. Dissolution behaviour and characterization of diazepam-pullanlan coground mixtures. Int J Pharm 1993; 89: 207–11
  • Chowdary KPR, Nagarajan M, Nalluri BN. Microencapsulation of nifedipine-MCC solvent deposited system for sustained release. Indian J Pharm Sci 1996; 58: 152–6
  • Daabis NA, Khalil SA, Naggar VF. Effect of urea, amidopyrine, phenazone and paracetamol on the solubility of some sparingly soluble antirheumatics. Candian J Pharm Sci 1976; 11: 114–7
  • Daabis NA, Mortada LM. Increased dissolution rate of phenacetin via solid dispersion. Sci Pharm 1980; 48: 16–23
  • Doshi DH, Ravis WR, Betageri GV. Carbamazepine and polyethylene glycol solid dispersions: Preparation, in vitro dissolution and characterization. Drug Dev Ind Pharm 1997; 23: 1167–76
  • El-Khodairy KA, El-Maradny HA, Etman MA. Application of fluidization technique for the preparation of fast release ketoprofen tablets. 2nd international conference of pharmaceutical science and technology, Alex. Alexandria, Egypt 25–27 October, 2000
  • Gabr KE, Borg ME. Characterization of hydrochloro-thiazide trometamol mixtures: Formulation of fast release soluble tablets. Pharm Ind 1999; 61: 281–5
  • Ghanem AH, El-Sabbagh H, Abdel-Alim H. Solubilization of flufenamic acid. Pharm Ind 1980; 42: 854–6
  • Giannola LI, Di Stefano V, De Caro V. White beeswax microspheres: A comparative in vitro evaluation of cumulative release of the anticancer agents flurouracil and florafur. Pharmazie 1993; 48: 123–6
  • Hassan EE, Eshra AG, Nada AH. Formulation of prolonged release lipid micropellets by emulsion congealing. Optimization of ketoprofen entrapment and release. Int J Pharm 1995; 121: 149–55
  • Ikeda K, Uekama K, Otagiri M. Inclusion complexes of beta-cyclodextrin with tranquilizing drugs phenothiazines in aqueous solution. Chem Pharm Bull 1975; 23: 188–95
  • Khan KA. The concept of dissolution efficiency. J Pharm Pharmacol 1975; 27: 48–9
  • Kibbe AH. Hand book of pharmaceutical excipients3rd. Pharmaceutical Press, London 2000a; 392–8
  • Kibbe AH. Hand book of pharmaceutical excipients3rd. Pharmaceutical Press, London 2000b; 345–8
  • Lanza FL. Gastrointestinal toxicity of newer NSAIDs. Am J Gastroentrol 1993; 88: 1318–23
  • Lin SY, Kao YH. Solid particulates of drug beta-cyclodextrin inclusion complexes directly prepared by a spray drying technique. Int J Pharm 1989; 56: 249–59
  • Martin A, Bustamanle P, Chun AHC. Physical pharmacy: Physical chemical principles in the pharmaceutical sciences4th. Lea & Febiger, Philadelphia, London 1993; 362–92
  • Meshali M, El-Dien EZ, Omar SA, Luzzi LA. A new approach to encapsulating nonsteroidal antiinflammatory drugs. I. Bioavailability and gastric ulcerogenic activity. J Microencapsulation 1987a; 4(2)133–40
  • Meshali M, El-Dien EZ, Omar SA, Luzzi LA. A new approach to encapsulating non steroidal anti-inflammatory drugs. II. Physicochemical properties. J. Microencapsulation 1987b; 4: 141–50
  • Meshali M, El-Sabbagh H. Biopharmaceutical study of acetylsalicylic acid tablets made from acrylic resin encapsulated particles. Acta Pharm Technol 1982; 28: 287–90
  • Meshali M, El-Sabbagh H, Foda A. Effect of encapsulation of flufenamic acid with acrylic resins on its bioavailability and gastric ulcerogenic activity in rats. Acta Pharm Technol 1983; 29: 217–9
  • Meshali MM, Gabr KE. Physical properties of fast release non reverting hydrochlorthiazide. Pharm Res 1992; 9: 960–2
  • Moffat AC, Jackson IV, Moss MS, Widdop B. Clarke's isolation and identification of drugs in pharmaceuticals, body fluids and post-mortem material2nd. The Pharmaceutical Press, London 1986; 727
  • Murthy RSR, Malhotra M, Miglani BD. Sustained release formulation of salbutamol sulfate. Drug Dev Ind Pharm 1991; 17: 1373–80
  • Nair R, Gonen S, Hoag SW. Influence of polyethylene glycol and povidone on the polymorphic transformation and solubility of carbamazepine. Int. J Pharm 2002; 240: 11–22
  • Nambu N, Kikuchi K, Tikuchi T, Takahashi Y, Ueda H, Nagai T. Influence of inclusion of nonsteroidal anti-inflammatory drugs with beta-cyclodextrin on the irritation to stomach of rats upon oral administration. Chem Pharm Bull 1978; 26: 3609–12
  • Parfitt K. The complete drug reference32nd. Pharmaceutical Press, London 1999; 51–2
  • Pongpaibul Y, Price JC, Whitworth CW. Preparation and evaluation of controlled release indomethacin microspheres. Drug Dev Ind Pharm 1984; 10: 1597–616
  • Prior S, Gamazo C, Irache JM, Merkle HP, Gander B. Gentamicin encapsulatiopn in PLA/PLGA microspheres in view of treating Brucella infections. Int J Pharm 2000; 196(25)115–25
  • Ruckmani K, Muneera MS. Enhancement of solubility and dissolution of carbamazepine by PEG 6000. East Pharm 2000; 43: 117–8
  • Saleh SI, Ahmed SM, Ahmed MO. Temazepam- beta-cyclodextrin and temazepam- microcrystalline cellulose ground mixtures formulated into tablets, capsules and suppositories. Bull Pharm Sci Assiut Univ 1994; 17: 57–64
  • Sayed HAM. Effect of process variables on the properties of coated resonates. I- Formulation of liquid dosage form. Egypt J Pharm Sci 1991; 32(3–4)937–50
  • Shah JC, Chen JR, Chow D. Preformulation study of etoposide. Part 2. Increased solubility and dissolution rate by solid dispersions. Int J Pharm 1995; 113(2)103–11
  • Shiotsu K, Arimori K, Nakano M. Absorption of diltiazem from the oral cavity and development of fast tablets. Jpn J Hosp Pharm 1995; 21(5)389–95
  • Sugimoto M, Okagaki T, Narisawa S, Kaida Y, Nakajima K. Improvement of dissolution characteristics and bioavailability of poorly water soluble drug by a novel cogrinding method using water soluble polymers. Int J Pharm 1998; 160: 11–9
  • Van den Mooter G, Augustijns P, Kinget R. Application of the thermodynamics of mobile order and disorder to explain the solubility of temazepam in aqueous solutions of polyethylene glycol 6000. Int J Pharm 1998; 164: 81–9
  • Youssef MK, Zein EE. Preformulation studies on mephenamic acid. Effect of certain additives and techniques on the dissolution and bioavailability of mephenamic acid capsule and tablet formulations. Pharm Ind 1992; 54: 373–7

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