Development and characterization of nanoparticulate formulation of a water soluble prodrug of dexamethasone by HIP complexation

References

• Agarwal S, Boddu SH, Jain R, Samanta S, Pal D, Mitra AK, Peptide prodrugs: Improved oral absorption of lopinavir, a HIV protease inhibitor. Int J Pharm, 2008;359:7–14
   Google Scholar
• Bala I, Hariharan S, Kumar MN. PLGA nanoparticles in drug delivery: The state of the art. Crit Rev Ther Drug Carrier Syst 2004; 21: 387–422
   PubMed Web of Science ®Google Scholar
• Bilati U, Allemann E, Doelker E. Nanoprecipitation versus emulsion-based techniques for the encapsulation of proteins into biodegradable nanoparticles and process-related stability issues. AAPS PharmSciTech 2005; 6: E594–604
   PubMed Web of Science ®Google Scholar
• Boddu SH, Jwala J, Vaishya R, Earla R, Karla PK, Pal D, Mitra AK. Novel nanoparticulate gel formulations of steroids for the treatment of macular edema. J Ocul Pharmacol Ther 2010; 26: 37–48
   PubMed Web of Science ®Google Scholar
• Chen Y, Siddalingappa B, Chan PH, Benson HA. Development of a chitosan-based nanoparticle formulation for delivery of a hydrophilic hexapeptide, dalargin. Biopolymers 2008a; 90: 663–70
   PubMed Web of Science ®Google Scholar
• Chen Y, Wang F, Benson HA. Effect of formulation factors on incorporation of the hydrophilic peptide dalargin into PLGA and mPEG-PLGA nanoparticles. Biopolymers 2008b; 90: 644–50
   PubMed Web of Science ®Google Scholar
• Cohen-Sela E, Chorny M, Koroukhov N, Danenberg HD, Golomb G. A new double emulsion solvent diffusion technique for encapsulating hydrophilic molecules in PLGA nanoparticles. J Controlled Release 2009; 133: 90–5
   PubMed Web of Science ®Google Scholar
• Dai WG, Dong LC. Characterization of physiochemical and biological properties of an insulin/lauryl sulfate complex formed by hydrophobic ion pairing. Int J Pharm 2007; 336: 58–66
   PubMed Web of Science ®Google Scholar
• Dalwadi G, Sunderland B. An ion pairing approach to increase the loading of hydrophilic and lipophilic drugs into PEGylated PLGA nanoparticles. Eur J Pharm Biopharm 2009; 71: 231–42
   PubMed Web of Science ®Google Scholar
• Del Pozo-Rodriguez A, Delgado D, Solinis MA, Gascon AR, Pedraz JL. Solid lipid nanoparticles for retinal gene therapy: Transfection and intracellular trafficking in RPE cells. Int J Pharm 2008; 360: 177–83
   PubMed Web of Science ®Google Scholar
• Feng L, De Dille A, Jameson VJ, Smith L, Dernell WS, Manning MC. Improved potency of cisplatin by hydrophobic ion pairing. Canc Chemother Pharmacol 2004; 54: 441–8
   PubMed Web of Science ®Google Scholar
• Gaudana R, Ananthula HK, Parenky A, Mitra AK. Ocular drug delivery. AAPS J 2010; 12: 348–60
   PubMed Web of Science ®Google Scholar
• Gaudana R, Jwala J, Boddu SH, Mitra AK. Recent perspectives in ocular drug delivery. Pharm Res 2009; 26: 1197–216
   PubMed Web of Science ®Google Scholar
• Halfter W. Change in embryonic eye size and retinal cell proliferation following intravitreal injection of glycosaminoglycans. Invest Ophthalmol Vis Sci 2008; 49: 3289–98
   PubMedGoogle Scholar
• Kansara V, Hao Y, Mitra AK. Dipeptide monoester ganciclovir prodrugs for transscleral drug delivery: Targeting the oligopeptide transporter on rabbit retina. J Ocul Pharmacol Ther 2007; 23: 321–34
   PubMed Web of Science ®Google Scholar
• Kim DH, Martin DC. Sustained release of dexamethasone from hydrophilic matrices using PLGA nanoparticles for neural drug delivery. Biomaterials 2006; 27: 3031–7
   PubMed Web of Science ®Google Scholar
• Kumar PS, Ramakrishna S, Saini TR, Diwan PV. Influence of microencapsulation method and peptide loading on formulation of poly(lactide-co-glycolide) insulin nanoparticles. Pharmazie 2006; 61: 613–17
   PubMed Web of Science ®Google Scholar
• Li Y, Pei Y, Zhang X, Gu Z, Zhou Z, Yuan W, Zhou J, Zhu J, Gao X. PEGylated PLGA nanoparticles as protein carriers: Synthesis, preparation and biodistribution in rats. J Controlled Release 2001; 71: 203–11
   PubMed Web of Science ®Google Scholar
• Majumdar S, Nashed YE, Patel K, Jain R, Itahashi M, Neumann DM, Hill JM, Mitra AK. Dipeptide monoester ganciclovir prodrugs for treating HSV-1-induced corneal epithelial and stromal keratitis: In vitro and in vivo evaluations. J Ocul Pharmacol Ther 2005; 21: 463–74
   PubMed Web of Science ®Google Scholar
• Meyer JD, Manning MC. Hydrophobic ion pairing: Altering the solubility properties of biomolecules. Pharm Res 1998; 15: 188–93
   PubMed Web of Science ®Google Scholar
• Perez C, Sanchez A, Putnam D, Ting D, Langer R, Alonso MJ. Poly(lactic acid)-poly(ethylene glycol) nanoparticles as new carriers for the delivery of plasmid DNA. J Controlled Release 2001; 75: 211–24
   PubMed Web of Science ®Google Scholar
• Singh SR, Grossniklaus HE, Kang SJ, Edelhauser HF, Ambati BK, Kompella UB. Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV. Gene Ther 2009; 16: 645–59
   PubMed Web of Science ®Google Scholar
• Sun S, Liang N, Piao H, Yamamoto H, Kawashima Y, Cui F. Insulin-S.O (sodium oleate) complex-loaded PLGA nanoparticles: Formulation, characterization and in vivo evaluation. J Microencapsul 2010; 27: 471–8
   PubMed Web of Science ®Google Scholar
• Talluri RS, Samanta SK, Gaudana R, Mitra AK. Synthesis, metabolism and cellular permeability of enzymatically stable dipeptide prodrugs of acyclovir. Int J Pharm 2008; 361: 118–24
   PubMed Web of Science ®Google Scholar
• Tan ML, Friedhuber AM, Dunstan DE, Choong PF, Dass CR. The performance of doxorubicin encapsulated in chitosan-dextran sulphate microparticles in an osteosarcoma model. Biomaterials 2010; 31: 541–51
   PubMed Web of Science ®Google Scholar
• Tewes F, Munnier E, Antoon B, Ngaboni Okassa L, Cohen-Jonathan S, Marchais H, Douziech-Eyrolles L, Souce M, Dubois P, Chourpa I. Comparative study of doxorubicin-loaded poly(lactide-co-glycolide) nanoparticles prepared by single and double emulsion methods. Eur J Pharm Biopharm 2007; 66: 488–92
   PubMed Web of Science ®Google Scholar
• Woitiski CB, Veiga F, Ribeiro A, Neufeld R. Design for optimization of nanoparticles integrating biomaterials for orally dosed insulin. Eur J Pharm Biopharm 2009; 73: 25–33
   PubMed Web of Science ®Google Scholar
• Yang L, Cui F, Shi K, Cun D, Wang R. Design of high payload PLGA nanoparticles containing melittin/sodium dodecyl sulfate complex by the hydrophobic ion-pairing technique. Drug Dev Ind Pharm 2009; 35: 959–68
   PubMed Web of Science ®Google Scholar
• Yoo HS, Choi HK, Park TG. Protein-fatty acid complex for enhanced loading and stability within biodegradable nanoparticles. J Pharm Sci 2001; 90: 194–201
   PubMed Web of Science ®Google Scholar
• Yuan H, Jiang SP, Du YZ, Miao J, Zhang XG, Hu FQ. Strategic approaches for improving entrapment of hydrophilic peptide drugs by lipid nanoparticles. Colloids Surf B Biointerfaces 2009; 70: 248–53
   PubMed Web of Science ®Google Scholar