150
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Development and evaluation of dual controlled release microballoons containing riboflavin and citric acid: in vitro and in vivo evaluation

&
Pages 442-454 | Received 04 Dec 2010, Accepted 28 Mar 2011, Published online: 10 May 2011

References

  • Akimoto M, Sato Y, Nemoto E, Todo H, Hasegawa T, Suugibayashi K. Pharmacokinetic profile of flavin adenine dinucleotide, flavin mononucleotide and riboflavin following intravenous administration of riboflavin or its coenzymes in rats. J Health Sci 2007; 53(3)332–8
  • Aulton ME. Pharmaceutics – the science of dosage form design, 2nd. Churchill Livingstone, London 2002; 207–8
  • Bajpai SK, Dubey S. Dynamic release of vitamin B2 from floating barium alginate beads for gastric delivery. J Macromol Sci, Part A: Pure Appl Chem 2008; 44: 1005–11
  • Bolton S. Pharmaceutical statistics: Practical and clinical applications. Marcel Dekker, New York 1997
  • Davis SS. Formulation strategies for absorption windows. Drug Discovery Today 2005; 10(4)249–57
  • Dominguez-Munoz JE, Leodolter A, Sauerbruch T, Malfartheriner P. A citric acid solution is an optimal test drink in the 13C-urea breath test for the diagnosis of Helicobacter pylori infection. Gut 1997; 40: 459–62
  • Dressman JB, Lennernas H. Oral drug absorption: Prediction and assessment. Marcel Dekker, New York 2000; 106: 155–79
  • El-Kamel AH, Sokar MS, Al gamal SS, Naggar VF. Preparation and evaluation of ketoprofen floating oral delivery system. Int J Pharm 2001; 220: 13–21
  • Fox PF, McSweeney PLH. Vitamin in milks and dairy products. In: Dairy chemistry and biochemistry, 1st. Blackie Academic & Professional, Madras 1998; 265–93
  • Gohel MC, Mehta PR, Dave RK, Bariya NH. A more relevant dissolution method for evaluation of floating drug delivery system. Disso Tech 2004; 11(4)22–5
  • Graham DY, Runke D, Anderson SY, Malaty HM, Klein PD. Critic acid as the test meal for the 13C-urea breath test. Am J Gastroenterol 1999; 94: 1214–17
  • Groning R, Berntgen M. Estimation of the gastric residence time of magnetic dosage forms using the Heidelberg capsule. Pharmazie 1996; 51: 328–31
  • Groning R, Werner M, Berntgen M, Geogorakis M. Peroral controlled release dosage forms with internal magnets and extracorporal magnetic guidance – investigations into the renal elimination of riboflavin. Eur J Pharm Biopharm 1996; 42: 25–8
  • Hamdani J, Goole J, Moes AJ, Amighi K. In vitro and in vivo evaluation of floating riboflavin pellets developed using the melt pelletization process. Int J Pharm 2006; 323: 86–92
  • Hunt JN, Knox MT. The regulation of gastric emptying of meals containing citric acid and salts of citric acid. J Physiol 1962; 163: 34–45
  • Iannuccelli V, Coppi G, Bernabei MT, Cameroni R. Air compartment multiple-unit system for prolonged gastric residence. Part I. Formulation study. Int J Pharm 1998a; 174: 47–54
  • Iannuccelli V, Coppi G, Leo E, Fontana F, Bernabei MT. PVP solid dispersions for the controlled release of furosemide from a floating multiple-unit system. Drug Dev Ind Pharm 2000; 26: 595–603
  • Iannuccelli V, Coppi G, Sansone R, Ferolla G. Air compartment multiple-unit system for prolonged gastric residence. Part II. In vivo evaluation. Int J Pharm 1998b; 174: 55–62
  • Ingani HM, Timmermans J, Moes AJ. Conception and in vivo investigation of peroral sustained release floating dosage forms with enhanced gastrointestinal transit. Int J Pharm 1987; 35: 157–64
  • Kagan L, Lapidot N, Afargan M, Kirmayer D, Moor E, Mardor Y, Friedman M, Hoffman A. Gastroretentive accordion pill: Enhancement of riboflavin bioavailability in humans. J Controlled Release 2006; 113: 208–15
  • Kawashima Y, Niwa T, Takeuchi H, Hino T, Itoh Y. Hollow microspheres for use as a floating controlled drug delivery system in the stomach. J Pharm Sci 1992; 81: 135–40
  • Krishna RR, Siraj P, Sastry CSP. Spectrophotometric determination of citric acid with metol and chromium (VI). Fresenius J Anal Chem 1980; 303(5)411
  • Martin A, Bustamante P, Chun A. Micromeritics. In: Physical pharmacy-physical chemical principles in the pharmaceutical sciences, 4th. Lippincott Williams and Wilkins, Baltimore 2002; 446–8
  • Rowe RC, Sheskey PJ, Owen SC. Handbook of pharmaceutical excipients, 5th. Pharmaceutical Press, London 2006; 185–7
  • Sato Y, Kawashima Y, Takeuchi H, Yamamoto H. The physicochemical properties to determine the buoyancy of hollow microspheres (microballoons) prepared by the emulsion solvent diffusion method. Eur J Pharm Biopharm 2003a; 55: 297–304
  • Sato Y, Kawashima Y, Takeuchi H, Yamamoto H. In vivo evaluation of riboflavin-containing microballoons for floating controlled drug delivery system in healthy human volunteers. J Controlled Release 2003b; 93: 39–47
  • Sato Y, Kawashima Y, Takeuchi H, Yamamoto H. In vitro and in vivo evaluation of riboflavin-containing microballoons for a floating controlled drug delivery system in healthy humans. Int J Pharm 2004a; 275: 97–107
  • Sato Y, Kawashima Y, Takeuchi H, Yamamoto H, Fujibayashi Y. Pharmacoscintigraphic evaluation of riboflavin-containing microballoons for a floating controlled drug delivery system in healthy humans. J Controlled Release 2004b; 98: 75–85
  • Shoaib MH, Tanzeen J, Merchant HA, Yousuf RI. Evaluation of drug release kinetics from ibuprofen matrix tablets using HPMC. Pak J Pharm Sci 2006; 19(2)119–24
  • Stops F, Fell JT, Collett JH, Martini LG, Sharma HL, Smith AM. The use of citric acid to prolong the in vivo gastro-retention of a floating dosage form in the fasted state. Int J Pharm 2006a; 308: 8–13
  • Stops F, Fell JT, Collett JH, Martini LG, Sharma HL, Smith AM. Citric acid prolongs the gastro-retention of a floating dosage form and increases bioavailability of riboflavin in the fasted state. Int J Pharm 2006b; 308: 14–24
  • Varshosaz J, Tabbakhian M, Zahrooni M. Development and characterization of floating microballoons for oral delivery of cinnarizine by a factorial design. J Microencapsulation 2007; 24(3)253–62
  • Yao H, Xu L, Han F, Che X, Dong Y, Wei M, Guan J, Shi X, Li S. A novel riboflavin gastro-mucoadhesive delivery system based on ion-exchange fiber. Int J Pharm 2008; 364(1)21–6
  • Yeo Y, Park K. Control of encapsulation efficiency and initial burst in polymeric microparticle systems. Arch Pharm Res 2004; 27(1)1–12

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.