389
Views
15
CrossRef citations to date
0
Altmetric
Research Article

Doxycycline delivery from PLGA microspheres prepared by a modified solvent removal method

, , , , , , & show all
Pages 344-352 | Received 24 Jul 2011, Accepted 05 Dec 2011, Published online: 23 Jan 2012

References

  • Ciombor DM, Jaklenec A, Liu AZ, Thanos C, Rahman N, Weston P, Aaron R, Mathiowitz E. Encapsulation of BSA using a modified W/O/O emulsion solvent removal method. J Microencapsul 2006; 23: 183–94
  • Dahl EL, Shock JL, Shenai BR, Gut J, Derisi JL, Rosenthal PJ. Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum. Antimicrob Agents Chemother 2006; 50: 3124–31
  • Feng K, Sun H, Bradley MA, Dupler EJ, Giannobile WV, Ma PX. Novel antibacterial nanofibrous PLLA scaffolds. J Control Release 2010; 146: 363–9
  • Freiberg S, Zhu XX. Polymer microspheres for controlled drug release. Int J Pharm 2004; 282: 1–18
  • Izumikawa S, Yoshioka S, Aso Y, Takeda Y. Preparation of poly(l-lactide) microspheres of different crystalline morphology and effect of crystalline morphology on drug release rate. J Control Release 1991; 15: 133–40
  • Lalloo DG, Shingadia D, Pasvol G, Chiodini PL, Whitty CJ, Beeching NJ, Hill DR, Warrell DA, Bannister BA. UK malaria treatment guidelines. J Infect 2007; 54: 111–21
  • Liu DZ, Chen WP, Lee CP, Wu SL, Wang YC, Chung TW. Effects of alginate coated on PLGA microspheres for delivery tetracycline hydrochloride to periodontal pockets. J Microencapsul 2004; 21: 643–52
  • Maatta M, Kari O, Tervahartiala T, Peltonen S, Kari M, Saari M, Sorsa T. Tear fluid levels of MMP-8 are elevated in ocular rosacea – Treatment effect of oral doxycycline. Graefes Arch Clin Exp Ophthalmol 2006; 244: 957–62
  • Mathiowitz E, Kline D, Langer R. Morphology of polyanhydride microsphere delivery systems. Scanning Microsc 1990; 4: 329–40
  • Mathiowitz E, Kreitz MR, Brannon-Peppas L. Microencapsulation. Encyclopedia of controlled drug delivery, E Mathiowitz. Wiley & Sons, New York 1999; 493–546
  • Mathiowitz E, Saltzman WM, Domb A, Dor P, Langer R. Polyanhydride microspheres as drug carriers. II. Microencapsulation by solvent removal. J Appl Polym Sci 1988; 35: 755–74
  • Mundargi RC, Srirangarajan S, Agnihotri SA, Patil SA, Ravindra S, Setty SB, Aminabhavi TM. Development and evaluation of novel biodegradable microspheres based on poly(d,l-lactide-co-glycolide) and poly(epsilon-caprolactone) for controlled delivery of doxycycline in the treatment of human periodontal pocket: In vitro and in vivo studies. J Control Release 2007; 119: 59–68
  • Patel P, Mundargi RC, Babu VR, Jain D, Rangaswamy V, Aminabhavi TM. Microencapsulation of doxycycline into poly(lactide-co-glycolide) by spray drying technique: Effect of polymer molecular weight on process parameters. J Appl Polym Sci 2008; 108: 4038–46
  • Quarterman MJ, Johnson DW, Abele DC, Lesher JL JR, Hull DS, Davis LS. Ocular rosacea. Signs, symptoms, and tear studies before and after treatment with doxycycline. Arch Dermatol 1997; 133: 49–54
  • Sandor M, Enscore D, Weston P, Mathiowitz E. Effect of protein molecular weight on release from micron-sized PLGA microspheres. J Control Release 2001; 76: 297–311
  • Sandor M, Harris J, Mathiowitz E. A novel polyethylene depot device for the study of PLGA and P(FASA) microspheres in vitro and in vivo. Biomaterials 2002; 23: 4413–23
  • Smith K, Leyden JJ. Safety of doxycycline and minocycline: A systematic review. Clin Ther 2005; 27: 1329–42
  • Stewart MW, Liesegang TJ, Schwam BL. Chlamydia conjunctivitis and central retinal vein occlusion. Am J Ophthalmol 2005; 140: 161–2
  • Tan LP, Hidayat A, Lao LL, Quah LF. Release of hydrophilic drug from biodegradable polymer blends. J Biomater Sci Polym Ed 2009; 20: 1381–92
  • Webber WL, Lago F, Thanos C, Mathiowitz E. Characterization of soluble, salt-loaded, degradable PLGA films and their release of tetracycline. J Biomed Mater Res 1998; 41: 18–29
  • Yuksel N, Tinusse T, Baykara T. Interaction between nicardipine hydrochloride and polymeric microspheres for a controlled release system. Int J Pharm 1996; 140: 145–54
  • Zeidner NS, Brandt KS, Dadey E, Dolan MC, Happ C, Piesman J. Sustained-release formulation of doxycycline hyclate for prophylaxis of tick bite infection in a murine model of Lyme borreliosis. Antimicrob Agents Chemother 2004; 48: 2697–9
  • Zhang Y, Zale S, Sawyer L, Bernstein H. Effects of metal salts on poly(DL-lactide-co-glycolide) polymer hydrolysis. J Biomed Mater Res 1997; 34: 531–8

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.