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Research Article

Spray-dried microparticles: a potential vehicle for oral delivery of vaccines

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Pages 388-397 | Received 02 Nov 2011, Accepted 12 Dec 2011, Published online: 27 Jan 2012

References

  • Akande J, Yeboah KG, Addo RT, Siddig A, Oettinger CW, D'Souza MJ. Targeted delivery of antigens to the gut-associated lymphoid tissues: II. Ex vivo evaluation of lectin-labelled albumin microspheres for targeted delivery of antigens to the M-cells of the Peyer's patches. J Microencapsul 2010; 27: 325–36
  • Andrianov AK, Payne LG. Polymeric carriers for oral uptake of microparticulates. Adv Drug Deliv Rev 1998; 34: 155–70
  • Baras B, Benoit M, Poulain-Godefroy O, Schacht A, Capron A, Gillard J, Riveau G. Vaccine properties of antigens entrapped in microparticles produced by spray-drying technique and using various polyester polymers. Vaccine 2000; 18: 1495–505
  • Bhowmik T, D'Souza B, Shashidharamurthy R, Oettinger C, Selvaraj P, D'Souza MJ. A novel microparticulate vaccine for melanoma cancer using transdermal delivery. J Microencapsul 2011; 28: 294–300
  • Bodmeier R, Chen HG, Paeratakul O. A novel approach to the oral delivery of micro- or nanoparticles. Pharm Res 1989; 6: 413–17
  • D'Souza B, Bhowmik T, Shashidharamurthy R, Oettinger C, Selvaraj P, D'Souza M. Oral microparticulate vaccine for melanoma using M-cell targeting. J Drug Target 2012; 20(2)166–73
  • Delgado A, Lavelle EC, Hartshorne M, Davis SS. PLG microparticles stabilised using enteric coating polymers as oral vaccine delivery systems. Vaccine 1999; 17: 2927–38
  • Do DP, Pai SB, Rizvi SA, D'Souza MJ. Development of sulforaphane-encapsulated microspheres for cancer epigenetic therapy. Int J Pharm 2010; 386: 114–21
  • Esposito E, Menegatti E, Cortesi R. Hyaluronan-based microspheres as tools for drug delivery: a comparative study. Int J Pharm 2005; 288: 35–49
  • Haddadi A, Farboud ES, Erfan M, Aboofazeli R. Preparation and characterization of biodegradable urea-loaded microparticles as an approach for transdermal delivery. J Microencapsul 2006; 23: 698–712
  • Hori M, Onishi H, Machida Y. Evaluation of Eudragit-coated chitosan microparticles as an oral immune delivery system. Int J Pharm 2005; 297: 223–34
  • Jain D, Panda AK, Majumdar DK. Eudragit S100 entrapped insulin microspheres for oral delivery. AAPS PharmSciTech 2005; 6: E100–7
  • Kaushik JK, Bhat R. Why is trehalose an exceptional protein stabilizer? An analysis of the thermal stability of proteins in the presence of the compatible osmolyte trehalose. J Biol Chem 2003; 278: 26458–65
  • Knoop KA, Kumar N, Butler BR, Sakthivel SK, Taylor RT, Nochi T, Akiba H, Yagita H, Kiyono H, Williams IR. RANKL is necessary and sufficient to initiate development of antigen-sampling M cells in the intestinal epithelium. J Immunol 2009; 183: 5738–47
  • Kunisawa J, Kurashima Y, Kiyono H. Gut-associated lymphoid tissues for the development of oral vaccines. Adv Drug Deliv Rev 2011, e-pub ahead of print
  • Lai YH, D'Souza MJ. Formulation and evaluation of an oral melanoma vaccine. J Microencapsul 2007; 24: 235–52
  • Lai YH, D'Souza MJ. Microparticle transport in the human intestinal M cell model. J Drug Target 2008; 16: 36–42
  • Lamprecht A, Yamamoto H, Takeuchi H, Kawashima Y. Microsphere design for the colonic delivery of 5-fluorouracil. J Control Release 2003; 90: 313–22
  • Men Y, Audran R, Thomasin C, Eberl G, Demotz S, Merkle HP, Gander B, Corradin G. MHC class I- and class II-restricted processing and presentation of microencapsulated antigens. Vaccine 1999; 17: 1047–56
  • Millqvist-Fureby A, Malmsten M, Bergenstahl B. Spray-drying of trypsin – Surface characterisation and activity preservation. Int J Pharm 1999; 188: 243–53
  • Morello M, Krone CL, Dickerson S, Howerth E, Germishuizen WA, Wong YL, Edwards D, Bloom BR, Hondalus MK. Dry-powder pulmonary insufflation in the mouse for application to vaccine or drug studies. Tuberculosis (Edinb) 2009; 89: 371–7
  • Nellore RV, Pande PG, Young D, Bhagat HR. Evaluation of biodegradable microspheres as vaccine adjuvant for hepatitis B surface antigen. J Parenter Sci Technol 1992; 46: 176–80
  • O'Hagan DT. Microparticles and polymers for the mucosal delivery of vaccines. Adv Drug Delivery Rev 1998; 34: 305–20
  • O'Hagan DT, Singh M. Microparticles as vaccine adjuvants and delivery systems. Expert Rev Vaccines 2003; 2: 269–83
  • Primard C, Rochereau N, Luciani E, Genin C, Delair T, Paul S, Verrier B. Traffic of poly(lactic acid) nanoparticulate vaccine vehicle from intestinal mucus to sub-epithelial immune competent cells. Biomaterials 2010; 31: 6060–8
  • Roth-Walter F, Bohle B, Scholl I, Untersmayr E, Scheiner O, Boltz-Nitulescu G, Gabor F, Brayden DJ, Jensen-Jarolim E. Targeting antigens to murine and human M-cells with Aleuria aurantia lectin-functionalized microparticles. Immunol Lett 2005; 100: 182–8
  • Roth-Walter F, Scholl I, Untersmayr E, Fuchs R, Boltz-Nitulescu G, Weissenbock A, Scheiner O, Gabor F, Jensen-Jarolim E. M cell targeting with Aleuria aurantia lectin as a novel approach for oral allergen immunotherapy. J Allergy Clin Immunol 2004; 114: 1362–8
  • Shakweh M, Besnard M, Nicolas V, Fattal E. Poly (lactide-co-glycolide) particles of different physicochemical properties and their uptake by peyer's patches in mice. Eur J Pharm Biopharm 2005; 61: 1–13
  • Shen H, Ackerman AL, Cody V, Giodini A, Hinson ER, Cresswell P, Edelson RL, Saltzman WM, Hanlon DJ. Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles. Immunology 2006; 117: 78–88
  • Vyas SP, Gupta PN. Implication of nanoparticles/microparticles in mucosal vaccine delivery. Expert Rev Vaccines 2007; 6: 401–18
  • Wright A, Mowrey-Mckee M. Comparative cytotoxicity potential of soft contact lens care products. Cutan Ocul Toxicol 2005; 24: 53–64
  • Xiang SD, Scholzen A, Minigo G, David C, Apostolopoulos V, Mottram PL, Plebanski M. Pathogen recognition and development of particulate vaccines: Does size matter?. Methods 2006; 40: 1–9
  • Zolnik BS, Raton JL, Burgess DJ. Application of USP apparatus 4 and in situ fiber optic analysis to microsphere, special edition on flow through cell, USP apparatus 4. Dissolution Technol 2005; 12: 11–14

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