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Research Article

Chitosan scaffolds with BMP-6 loaded alginate microspheres for periodontal tissue engineering

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Pages 770-780 | Received 02 Jan 2012, Accepted 09 Apr 2012, Published online: 21 May 2012

References

  • Akman AC, Tığlı RS, Gümüşderelioğlu M, Nohutcu RM. bFGF loaded Ha chitosan: A promising scaffold for periodontal tissue engineering. J Biomed Mater Res, Part A 2010a; 92: 953–62
  • Akman AC, Tığlı RS, Gümüşderelioğlu M, Nohutcu RM. Bone morphogenetic protein 6 loaded chitosan scaffolds enhance the osteoblastic characteristics of Mc3t3 E1 cells. Artif Organs 2010b; 34: 65–74
  • Amar S, Han X. The impact of periodontal infection on systemic diseases. Med Sci Monit 2003; 9: RA291–9
  • Amidi M, Mastrobattista E, Jiskoot W, Hennink WE. Chitosan-based delivery systems for protein therapeutics and antigens. Adv Drug Delivery Rev 2010; 62: 59–82
  • Berkland C, Kipper MJ, Narasimhan B, Kim K, Pack DW. Microsphere size, precipitation kinetics and drug distribution control drug release from biodegradable polyanhydride microspheres. J Controlled Release 2004; 94: 129–41
  • Bock N, Woodruff MA, Hutmacher DW, Dargaville TR. Electrospraying, a reproducible method for production of polymeric microspheres for biomedical applications. Polymers 2011; 3: 131–49
  • Cheng SL, Lai CF, Blystone SD, Avioli LV. Bone mineralization and osteoblast differentiation are negatively modulated by integrin αvβ3. J Bone Miner Res 2001; 16: 277–88
  • Ciofani G, Raffa V, Menciassi A, Micera S, Dario P. A drug delivery system based on alginate microspheres: Mass-transport test and in vitro validation. Biomed Microdevices 2007; 9: 395–403
  • Feltkamp T. Conjugation of fluorescein isothiocyanate to antibodies: II. A reproducible method. Immunology 1970; 18: 875–81
  • Friedman MS, Long MW, Hankenson KD. Osteogenic differentiation of human mesenchymal stem cells is regulated by bone morphogenetic protein-6. J Cell Biochem 2006; 98: 538–54
  • Gerlier D, Thomasset N. Use of MTT colorimetric assay to measure cell activation. J Immunol Methods 1986; 94: 57–63
  • Grasser WA, Orlic I, Borovecki F, Riccardi K, Simic P, Vukicevic S, Paralkar VM. Bmp-6 exerts its osteoinductive effect through activation of IgF-I and EgF pathways. Int Orthop 2007; 31: 759–65
  • Hamilton V, Yuan Y, Rigney D, Puckett A, Ong J, Yang Y, Elder S, Bumgardner J. Characterization of chitosan films and effects on fibroblast cell attachment and proliferation. J Mat Sci-Mat Med 2006; 17: 1373–81
  • Huang KK, Shen C, Chiang CY, Hsieh YD, Fu E. Effects of bone morphogenetic protein 6 on periodontal wound healing in a fenestration defect of rats. J Periodontal Res 2005; 40: 1–10
  • Izumi Y, Aoki A, Yamada Y, Kobayashi H, Iwata T, Akizuki T, Suda T, Nakamura S, Wara-Aswapati N, Ueda M, et al. Current and future periodontal tissue engineering. Periodontology 2000 2011; 56: 166–87
  • Jaworek A. Electrostatic micro- and nanoencapsulation and electroemulsification: A brief review. J Microencapsulation 2008; 25: 443–68
  • Jay SM, Saltzman WM. Controlled delivery of vegf via modulation of alginate microparticle ionic crosslinking. J Controlled Release 2009; 134: 26–34
  • Kaigler D, Cirelli JA, Giannobile WV. Growth factor delivery for oral and periodontal tissue engineering. Expert Opin Drug Deliv 2006; 3: 647–62
  • Karaöz E, Aksoy A, Ayhan S, Sarıboyacı AE, Kaymaz F, Kasap M. Characterization of mesenchymal stem cells from rat bone marrow: Ultrastructural properties, differentiation potential and immunophenotypic markers. Histochem Cell Biol 2009; 132: 533–46
  • Korsmeyer RW, Gurny R, Doelker E, Buri P, Peppas NA. Mechanisms of solute release from porous hydrophilic polymers. Int J Pharm 1983; 15: 25–35
  • Lee K, Silva E, Mooney D. Growth factor delivery-based tissue engineering: General approaches and a review of recent developments. J R Soc Interface 2010; 8: 153–70
  • Li BZ, Wang LJ, Li D, Bhandari B, Li SJ, Lan Y, Chen XD, Mao ZH. Fabrication of starch-based microparticles by an emulsification-crosslinking method. J Food Eng 2009; 92: 250–4
  • Mejia AF, He P, Luo D, Marquez M, Cheng Z. Uniform discotic wax particles via electrospray emulsification. J Colloid Interface Sci 2009; 334: 22–8
  • Moebus K, Siepmann J, Bodmeier R. Novel preparation techniques for alginate-poloxamer microparticles controlling protein release on mucosal surfaces. Eur J Pharm Sci 2012; 45, 3: 358–66
  • Nakahara T. A review of new developments in tissue engineering therapy for periodontitis. Dent Clin N Am 2006; 50: 265–76
  • Nakashima M, Tachibana K, Iohara K, Ito M, Ishikawa M, Akamine A. Induction of reparative dentin formation by ultrasound-mediated gene delivery of growth/differentiation factor 11. Hum Gene Ther 2003; 14: 591–7
  • Peppas NA, Brannon-Peppas L. Water diffusion and sorption in amorphous macromolecular systems and foods. J Food Eng 1994; 22: 189–210
  • Renvert S, Persson GR. Supportive periodontal therapy. Periodontology 2000 2004; 36: 179–95
  • Salib N, El-Menshawy M, Ismail A. Utilization of sodium alginate in drug microencapsulation. Pharm Ind 1978; 40: 1230–4
  • Sill TJ, von Recum HA. Electrospinning: Applications in drug delivery and tissue engineering. Biomaterials 2008; 29: 1989–2006
  • Suck K, Behr L, Fischer M, Hoffmeister H, Griensven MV, Stahl F, Scheper T, Kasper C. Cultivation of MC3T3 E1 cells on a newly developed material (Sponceram®) using a rotating bed system bioreactor. J Biomed Mater Res A 2007; 80: 268–75
  • Suksamran T, Opanasopit P, Rojanarata T, Ngawhirunpat T, Ruktanonchai U, Supaphol P. Biodegradable alginate microparticles developed by electrohydrodynamic spraying techniques for oral delivery of protein. J Microencapsulation 2009; 26: 563–70
  • Tığlı RS, Karakeçili A, Gümüşderelioğlu M. In vitro characterization of chitosan scaffolds: influence of composition and deacetylation degree. J Mat Sci Mat Med 2007; 18: 1665–74
  • Tığlı RS, Gümüşderelioğlu M. Evaluation of alginate-chitosan semi IPNs as cartilage scaffolds. J Mat Sci: Mat Med 2009; 20: 699–709
  • Voo WP, Ravindra P, Tey BT, Chan ES. Comparison of alginate and pectin based beads for production of poultry probiotic cells. J Biosci Bioeng 2011; 111: 294–9
  • Xie J, Wang CH. Electrospray in the dripping mode for cell microencapsulation. J Colloid Interface Sci 2007a; 312: 247–55
  • Xie J, Wang CH. Encapsulation of proteins in biodegradable polymeric microparticles using electrospray in the taylor cone jet mode. Biotechnol Bioeng 2007b; 97: 1278–90
  • Yao J, Kuang Lim L, Xie J, Hua J, Wang CH. Characterization of electrospraying process for polymeric particle fabrication. J Aerosol Sci 2008; 39: 987–1002
  • Ye M, Kim S, Park K. Issues in long-term protein delivery using biodegradable microparticles. J Controlled Release 2010; 146: 241–60
  • Yılgör P, Tuzlakoğlu K, Reis RL, Hasırcı N, Hasırcı V. Incorporation of sequential BMP-2/BMP-7 delivery system into chitosan-based scaffolds for bone tissue engineering. Biomaterials 2009; 30(21)3551–9

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