304
Views
23
CrossRef citations to date
0
Altmetric
Research Article

Formulation of meningococcal capsular polysaccharide vaccine-loaded microparticles with robust innate immune recognition

, , , &
Pages 28-41 | Received 31 Jan 2012, Accepted 23 Apr 2012, Published online: 01 Jun 2012

References

  • Abramoff MD, Magelhaes PJ, Ram SJ. Image processing with image. J Biophoton Int 2004; 11: 36–42
  • Al-Nasiry S, Geusens N, Hanssens M, Luyten C, Pijnenborg R. The use of Alamar Blue assay for quantitative analysis of viability, migration and invasion of choriocarcinoma cells. Hum Reprod 2007; 22: 1304–9
  • Arbabi S, Rosengart MR, Garcia I, Jelacic S, Maier RV. Priming interleukin 8 production: Role of platelet-activating factor and p38. Arch Surg 1999; 134: 1348–53
  • Arnida Malugin A, Ghandehari H. Cellular uptake and toxicity of gold nanoparticles in prostate cancer cells: A comparative study of rods and spheres. J Appl Toxicol 2010; 30: 212–17
  • Barin JG, Baldeviano GC, Talor MV, Wu L, Ong S, Quader F, Chen P, Zheng D, Caturegli P, Rose NR, et al. Macrophages participate in IL-17-mediated inflammation. Eur J Immunol 2012; 42: 726–36
  • Barton GM, Medzhitov R. Control of adaptive immune responses by Toll-like receptors. Curr Opin Immunol 2002; 14: 380–3
  • Bejugam NK, Uddin AN, Gayakwad SG, D'Souza MJ. Formulation and evaluation of albumin microspheres and its enteric coating using a spray-dryer. J Microencapsul 2008; 25: 577–83
  • Blander JM, Medzhitov R. On regulation of phagosome maturation and antigen presentation. Nat Immunol 2006; 7: 1029–35
  • Brandtzaeg P. Host response to Neisseria meningitidis lacking lipopolysaccharides. Expert Rev Anti Infect Ther 2003; 1: 589–96
  • Brandtzaeg P. Induction of secretory immunity and memory at mucosal surfaces. Vaccine 2007; 25: 5467–84
  • Brunskill NJ. Albumin receptors-structure and function, in cellular proteins and their fatty acids in health and disease. Weinheim, FRG: Wiley-VCH Verlag GmbH & Co, KGaA 2004
  • Castellheim A, Brekke OL, Espevik T, Harboe M, Mollnes TE. Innate immune responses to danger signals in systemic inflammatory response syndrome and sepsis. Scand J Immunol 2009; 69: 479–91
  • Chiarella P, Massi E, de Robertis M, Signori E, Fazio VM. Adjuvants in vaccines and for immunisation: Current trends. Expert Opin Biol Ther 2007; 7: 1551–62
  • Chiavaroli C, Moore A. An hypothesis to link the opposing immunological effects induced by the bacterial lysate OM-89 in urinary tract infection and rheumatoid arthritis. BioDrugs 2006; 20: 141–9
  • Chippaux JP, Garba A, Ethevenaux C, Campagne G, de Chabalier F, Djibo S, Nicolas P, Ali H, Charrondiere M, Ryall R, et al. Immunogenicity, safety, and memory of different schedules of Neisseria meningitidis A/C-diphtheria toxoid conjugate vaccine in infants in Niger. Vaccine 2004; 22: 3303–11
  • Choudhury B, Kahler CM, Datta A, Stephens DS, Carlson RW. The structure of the L9 immunotype lipooligosaccharide from Neisseria meningitidis NMA Z2491. Carbohydr Res 2008; 343: 2971–9
  • Cleland JL, Daugherty A, Mrsny R. Emerging protein delivery methods. Curr Opin Biotechnol 2001; 12: 212–19
  • Crotzer VL, Blum JS. Autophagy and adaptive immunity. Immunology 2010; 131: 9–17
  • de-Deus G, Gurgel-Filho ED, Magalhaes KM, Coutinho-Filho T. A laboratory analysis of gutta-percha-filled area obtained using thermafil, system B and lateral condensation. Int Endod J 2006; 39: 378–83
  • Diwan M, Elamanchili P, Lane H, Gainer A, Samuel J. Biodegradable nanoparticle mediated antigen delivery to human cord blood derived dendritic cells for induction of primary T cell responses. J Drug Target 2003; 11: 495–507
  • Elias D, Akuffo H, Britton S. Helminthes could influence the outcome of vaccines against TB in the tropics. Parasite Immunol 2006; 28: 507–13
  • Fu K, Klibanov AM, Langer R. Protein stability in controlled-release systems. Nat Biotech 2000; 18: 24–5
  • Garlapati S, Facci M, Polewicz M, Strom S, Babiuk LA, Mutwiri G, Hancock RE, Elliott MR, Gerdts V. Strategies to link innate and adaptive immunity when designing vaccine adjuvants. Vet Immunol Immunopathol 2009; 128: 184–91
  • Granoff DM. Relative importance of complement-mediated bactericidal and opsonic activity for protection against meningococcal disease. Vaccine 2009; 27(Suppl. 2)B117–25
  • Gudlavalleti SK, Szymanski CM, Jarrell HC, Stephens DS. In vivo determination of Neisseria meningitidis serogroup a capsular polysaccharide by whole cell high-resolution magic angle spinning NMR spectroscopy. Carbohydr Res 2006; 341: 557–62
  • Hamid R, Rotshteyn Y, Rabadi L, Parikh R, Bullock P. Comparison of Alamar Blue and MTT assays for high through-put screening. Toxicol In Vitro 2004; 18: 703–10
  • Ireland JM, Unanue ER. Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells. J Exp Med 2011; 208: 2625–32
  • Jiang ZH, Koganty RR. Synthetic vaccines: The role of adjuvants in immune targeting. Curr Med Chem 2003; 10: 1423–39
  • Kaplan SL, Schutze GE, Leake JAD, Barson WJ, Halasa NB, Byington CL, Woods CR, Tan TQ, Hoffman JA, Wald ER, et al. Multicenter surveillance of invasive meningococcal infections in children. Pediatrics 2006; 118: E979–84
  • Kawai T, Akira S. The roles of TLRs, RLRs and NLRs in pathogen recognition. Int Immunol 2009; 21: 317–37
  • Kensil CR, Mo AX, Truneh A. Current vaccine adjuvants: An overview of a diverse class. Front Biosci 2004; 9: 2972–88
  • Lai YH, D'Souza MJ. Microparticle transport in the human intestinal M cell model. J Drug Target 2008; 16: 36–42
  • Lesinski GB, Westerink MA. Novel vaccine strategies to T-independent antigens. J Microbiol Methods 2001; 47: 135–49
  • Levine B, Deretic V. Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol 2007; 7: 767–77
  • Makwana N, Riordan FA. Bacterial meningitis: The impact of vaccination. CNS Drugs 2007; 21: 355–66
  • McNeela EA, Mills KH. Manipulating the immune system: Humoral versus cell-mediated immunity. Adv Drug Deliv Rev 2001; 51: 43–54
  • Moll H. Antigen delivery by dendritic cells. Int J Med Microbiol 2004; 294: 337–44
  • Munz C. Autophagy and antigen presentation. Cell Microbiol 2006; 8: 891–8
  • Nijnik A, Hancock RE. The roles of cathelicidin LL-37 in immune defences and novel clinical applications. Curr Opin Hematol 2009; 16: 41–7
  • Pasare C, Medzhitov R. Toll-like receptors: Linking innate and adaptive immunity. Adv Exp Med Biol 2005; 560: 11–18
  • Peng H, Huang Y, Rose J, Erichsen D, Herek S, Fujii N, Tamamura H, Zheng J. Stromal cell-derived factor 1-mediated CXCR4 signaling in rat and human cortical neural progenitor cells. J Neurosci Res 2004; 76: 35–50
  • Plant L, Sundqvist J, Zughaier S, Lovkvist L, Stephens DS, Jonsson AB. Lipooligosaccharide structure contributes to multiple steps in the virulence of Neisseria meningitidis. Infect Immun 2006; 74: 1360–7
  • Prokopowicz ZM, Arce F, Biedron R, Chiang CL, Ciszek M, Katz DR, Nowakowska M, Zapotoczny S, Marcinkiewicz J, Chain BM. Hypochlorous acid: A natural adjuvant that facilitates antigen processing, cross-priming, and the induction of adaptive immunity. J Immunol 2010; 184: 824–35
  • Pulendran B, Ahmed R. Translating innate immunity into immunological memory: Implications for vaccine development. Cell 2006; 124: 849–63
  • Shepard CW, Rosenstein NE, Fischer M. Neonatal meningococcal disease in the United States, 1990 to 1999. Pediatr Infect Dis J 2003; 22: 418–22
  • Sims K, Haynes CA, Kelly S, Allegood JC, Wang E, Momin A, Leipelt M, Reichart D, Glass CK, Sullards MC, et al. Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy. J Biol Chem 2010; 285: 38568–79
  • Spinosa MR, Progida C, Tala A, Cogli L, Alifano P, Bucci C. The Neisseria meningitidis capsule is important for intracellular survival in human cells. Infect Immun 2007; 75: 3594–603
  • Stein KE. Thymus-independent and thymus-dependent responses to polysaccharide antigens. J Infect Dis 1992; 165(Suppl. 1)S49–52
  • Stephens DS, Greenwood B, Brandtzaeg P. Epidemic meningitis, meningococcaemia, and Neisseria meningitidis. Lancet 2007; 369: 2196–210
  • Svennerholm L. Quantitative estimation of sialic acids. II. A colorimetric resorcinol-hydrochloric acid method. Biochim Biophys Acta 1957; 24: 604–11
  • Tang T, Zhang J, Yin J, Staszkiewicz J, Gawronska-Kozak B, Jung DY, Ko HJ, Ong H, Kim JK, Mynatt R, et al. Uncoupling of inflammation and insulin resistance by NF-kappaB in transgenic mice through elevated energy expenditure. J Biol Chem 2010; 285: 4637–44
  • Tzeng YL, Datta AK, Strole CA, Lobritz MA, Carlson RW, Stephens DS. Translocation and surface expression of lipidated serogroup B capsular polysaccharide in Neisseria meningitidis. Infect Immun 2005; 73: 1491–505
  • Uddin AN, Bejugam NK, Gayakwad SG, Akther P, D'Souza MJ. Oral delivery of gastro-resistant microencapsulated typhoid vaccine. J Drug Target 2009; 17: 553–60
  • van der Lubben IM, Verhoef JC, van Aelst AC, Borchard G, Junginger HE. Chitosan microparticles for oral vaccination: Preparation, characterization and preliminary in vivo uptake studies in murine Peyer's patches. Biomaterials 2001; 22: 687–94
  • Xu Y, Jagannath C, Liu XD, Sharafkhaneh A, Kolodziejska KE, Eissa NT. Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity 2007; 27: 135–44
  • Yeboah KG, D'Souza MJ. Evaluation of albumin microspheres as oral delivery system for mycobacterium tuberculosis vaccines. J Microencapsul 2009; 26: 166–79
  • Zughaier SM. Neisseria meningitidis capsular polysaccharides induce inflammatory responses via TLR2 and TLR4-MD-2. J Leukoc Biol 2011; 89: 469–80
  • Zughaier S, Agrawal S, Stephens DS, Pulendran B. Hexa-acylation and KDO(2)-glycosylation determine the specific immunostimulatory activity of Neisseria meningitidis lipid A for human monocyte derived dendritic cells. Vaccine 2006; 24: 1291–7
  • Zughaier SM, Ryley HC, Jackson SK. A melanin pigment purified from an epidemic strain of Burkholderia cepacia attenuates monocyte respiratory burst activity by scavenging superoxide anion. Infect Immun 1999; 67: 908–13
  • Zughaier SM, Shafer WM, Stephens DS. Antimicrobial peptides and endotoxin inhibit cytokine and nitric oxide release but amplify respiratory burst response in human and murine macrophages. Cell Microbiol 2005; 7: 1251–62
  • Zughaier S, Steeghs L, van Der Ley P, Stephens DS. TLR4-dependent adjuvant activity of Neisseria meningitidis lipid A. Vaccine 2007; 25: 4401–9
  • Zughaier SM, Svoboda P, Pohl J, Stephens DS, Shafer WM. The human host defense peptide LL-37 interacts with Neisseria meningitidis capsular polysaccharides and inhibits inflammatory mediators release. PLoS One 2010; 5: e13627
  • Zughaier SM, Tzeng YL, Zimmer SM, Datta A, Carlson RW, Stephens DS. Neisseria meningitidis lipooligosaccharide structure-dependent activation of the macrophage CD14/Toll-like receptor 4 pathway. Infect Immun 2004; 72: 371–80

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.