237
Views
12
CrossRef citations to date
0
Altmetric
Research Article

Factorial design analysis and optimisation of alginate–Ca–chitosan microspheres

, , , &
Pages 81-92 | Received 17 Jan 2012, Accepted 28 May 2012, Published online: 03 Jul 2012

References

  • Ashford M, Fell JT, Attwood D, Sharma H, Woodhead PJ. An in vivo investigation into the suitability of pH dependent polymers for colonic targeting. Int J Pharm 1993; 95(1–3)193–9
  • Bajpai SK, Sharma S. Investigation of swelling/degradation behaviour of alginate beads crosslinked with Ca2+ and Ba2+ ions. React Funct Polym 2004; 59(2)129–40
  • Bandi N, Wei W, Roberts CB, Kotra LP, Kompella UB. Preparation of budesonide– and indomethacin–hydroxypropyl-β-cyclodextrin (HPBCD) complexes using a single-step, organic-solvent-free supercritical fluid process. Eur J Pharm Sci 2004; 23(2)159–68
  • Borges O, Borchard G, Verhoef JC, De Sousa A, Junginger HE. Preparation of coated nanoparticles for a new mucosal vaccine delivery system. Int J Pharm 2005; 299(1–2)155–66
  • Coppi G, Iannuccelli V, Bernabei MT, Cameroni R. Alginate microparticles for enzyme peroral administration. Int J Pharm 2002; 242(1–2)263–6
  • Coppi G, Iannuccelli V, Leo E, Bernabei MT, Cameroni R. Chitosan-alginate microparticles as a protein carrier. Drug Dev Ind Pharm 2001; 27(5)393–400
  • Council of Europe. European pharmacopoeia7th. Council of Europe, StrasbourgFrance 2010
  • De Jaeghere F, Allemann E, Cerny R, Galli B, Steulet AF, Muller I, Schutz H, Doelker E, Gurny R. pH-Dependent dissolving nano- and microparticles for improved peroral delivery of a highly lipophilic compound in dogs. AAPS PharmSci 2001; 3(1)E8
  • de Mello VA, Ricci-Júnior E. Encapsulation of naproxen in nanostructured system: Structural characterization and in vitro release studies. Quim Nova 2011; 34: 933–9
  • Dubey RR, Parikh RH. Studies of PLGA microspheres. Pharm Technol Eur 2004; 16(5)23–34
  • Glavas Dodov M, Calis S, Crcarevska MS, Geskovski N, Petrovska V, Goracinova K. Wheat germ agglutinin-conjugated chitosan-Ca-alginate microparticles for local colon delivery of 5-FU: Development and in vitro characterization. Int J Pharm 2009; 381(2)166–75
  • González-Rodríguez ML, Holgado MA, Sánchez-Lafuente C, Rabasco AM, Fini A. Alginate/chitosan particulate systems for sodium diclofenac release. Int J Pharm 2002; 232(1–2)225–34
  • Goracinova K. Formulation and preparation of spray-dried alginate–Ca microparticles. Patent no. MP/MK/05/01/FF/BE/01/IP, 2005.
  • Goracinova K, Glavas-Dodov M, Simonoska-Crcarevska M, Geskovski N. 2012. Drug targeting in IBD treatment – Existing and new approaches. In: Karoui S, ed. Inflammatory bowel disease – Advances in pathogenesis and management. In Tech Europe, Rijeka, Croatia, pp. 301-32, ISBN: 978-953-307-891-5.
  • Gottlieb N, Schwartzbach C. 2004. Development of an internal mixing two-fluid nozzle by systematic variation of internal parts. 19th Annual Meeting of ILASS (Europe) Conference Proceedings, Nottingham, UK, p. 97.
  • Korsmeyer RW, Gurny R, Doelker E. Mechanisms of solute release from porous hydrophilic polymers. Int J Pharm 1983; 15(1)25–35
  • Lamprecht A, Schäfer U, Lehr CM. Size-dependent bioadhesion of micro- and nanoparticulate carriers to the inflamed colonic mucosa. Pharm Res 2001a; 18(6)788–93
  • Lamprecht A, Ubrich N, Yamamoto H, Schäfer U, Takeuchi H, Maincent P, Kawashima Y, Lehr CM. Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease. J Pharmacol Exp Ther 2001b; 299(2)775–81
  • Martinac A, Filipovic-Grcic J, Perissutti B, Voinovich D, Pavelic Z. Spray-dried chitosan/ethylcellulose microspheres for nasal drug delivery: Swelling study and evaluation of in vitro drug release properties. J Microencapsul 2005; 22(5)549–61
  • Myers HR, Montgomery CD. Response surface methodology: Process and product optimization using designed experiments. Wiley & Sons, New York 2002
  • Nakase H, Okazaki K, Tabata Y, Uose S, Ohana M, Uchida K, Nishi T, Debreceni AS, Itoh T, Kawanami C, et al. An oral drug delivery system targeting immune-regulating cells ameliorates mucosal injury in trinitrobenzene sulfonic acid-induced colitis. J Pharmacol Exp Ther 2001; 297(3)1122–8
  • Peppas NA. Analysis of Fickian and non-Fickian drug release from polymers. Pharm Acta Helv 1985; 60(4)110–11
  • Peppas NA, Sahlin JJ. A simple equation for the description of solute release. III. Coupling of diffusion and relaxation. Int J Pharm 1989; 57(2)169–72
  • Prakobvaitayakit M, Nimmannit U. Optimization of polylactic-co-glycolic acid nanoparticles containing itraconazole using 23 factorial design. AAPS PharmSciTech 2003; 4(4)565–73
  • Ritger PL, Peppas NA. A simple equation for desciption of solute release I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. J Control Release 1987; 5(1)23–36
  • Rodríguez M, Vila-Jato JL, Torres D. Design of a new multiparticulate system for potential site-specific and controlled drug delivery to the colonic region. J Control Release 1998; 55(1)67–77
  • Sankalia MG, Mashru RC, Sankalia JM, Sutariya VB. Reversed chitosan–alginate polyelectrolyte complex for stability improvement of alpha-amylase: Optimization and physicochemical characterization. Eur J Pharm Biopharm 2007; 65(2)215–32
  • Simonoska Crcarevska M, Glavas Dodov M, Goracinova K. Chitosan coated Ca–alginate microparticles loaded with budesonide for delivery to the inflamed colonic mucosa. Eur J Pharm Biopharm 2008; 68(3)565–78
  • Sutherland IW. Alginates. Biomaterials, novel materials from biological sources, D Byrom. Stockton, New York 1991; 309–31
  • Tabata Y, Inoue Y, Ikada Y. Size effect on systemic and mucosal immune responses induced by oral administration of biodegradable microspheres. Vaccine 1996; 14(17–18)1677–85
  • Tajber L, Corrigan DO, Corrigan OI, Healy AM. Spray drying of budesonide, formoterol fumarate and their composites—I. Physicochemical characterisation. Int J Pharm 2009; 367(1–2)79–85
  • Toti US, Aminabhavi TM. Modified guar gum matrix tablet for controlled release of diltiazem hydrochloride. J Control Release 2004; 95(3)567–77
  • Wong SM, Kellaway IW, Murdan S. Enhancement of the dissolution rate and oral absorption of a poorly water soluble drug by formation of surfactant-containing microparticles. Int J Pharm 2006; 317(1)61–8

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.