167
Views
1
CrossRef citations to date
0
Altmetric
Research Article

Utilization of catalytic hydrolysis of ethyl acetate for solvent removal during microencapsulation

, &
Pages 346-355 | Received 07 Jun 2012, Accepted 17 Sep 2012, Published online: 18 Oct 2012

References

  • Allhenn D, Lamprecht A. Microsphere preparation using the untoxic solvent glycofurol. Pharm Res 2011; 28: 563–71
  • Bempong DK, Bhattacharyya L. Development and validation of stability-indicating high-performance liquid chromatographic assay for ketoprofen topical penetrating gel. J Chromatogr A 2005; 1073: 341–6
  • Blanco-Prieto MJ, Fattal E, Gulik A, Dedieu JC, Roques BP, Couvreur P. Characterization and morphological analysis of cholecystokinin derivative peptide-loaded poly(lactide-co-glycolide) microspheres prepared by a water-in-oil-in-water emulsion solvent evaporation method. J Controlled Release 1997; 43: 81–7
  • Bodmeier R, McGinity JW. Polylactic acid microspheres containing quinidine base and quinidine sulfate prepared by the solvent evaporation technique: II. Some process parameters influencing the preparation and properties of microcapsules. J Microencapsulation 1987; 4: 289–97
  • Chang J, Hughes P. Oil-in-water method for making alpha-2 agonist polymeric drug delivery systems. US Patent 7589057, 2009
  • Daeseleire E, Mortier L, de Ruyck H, Geerts N. Determination of Flunixin and ketoprofen in milk by liquid chromatography–tandem mass spectrometry. Anal Chim Acta 2003; 488: 25–34
  • Freitas S, Merkle HP, Gander B. Microencapsulation by solvent extraction/evaporation: Reviewing the state of the art of microsphere preparation process technology. J Controlled Release 2005; 102: 313–32
  • Freytag T, Dashevsky A, Tillman L, Hardee GE, Bodmeier R. Improvement of the encapsulation efficiency of oligonucleotide-containing biodegradable microspheres. J Controlled Release 2000; 69: 197–207
  • Gonnade RG, Iwama S, Sugiwake R, Manoj K, Takahashi H, Tsue H, Tamura R. Occurrence of spontaneous resolution of ketoprofen with a racemic crystal structure by simple crystallization under nonequilibrium preferential enrichment conditions. Chem Commun 2012; 48: 2791–3
  • Im HY, Kim J, Sah H. Another paradigm in solvent extraction-based microencapsulation technologies. Biomacromolecules 2010; 11: 776–86
  • Jones DS, Pearce KJ. An investigation of the effects of some process variables on the microencapsulation of propranolol hydrochloride by the solvent evaporation method. Int J Pharm 1995; 118: 199–205
  • Lagarce F, Renaud P, Faisant N, Nicolas G, Cailleux A, Richard J, Menei P, Benoit JP. Baclofen-loaded microspheres: Preparation and efficacy testing in a new rabbit model. Eur J Pharm Biopharm 2005; 59: 449–59
  • Lee H, Lee S, Bhattacharjee H, Sah H. Application of acid-catalyzed hydrolysis of dispersed organic solvent in developing new microencapsulation process technology. J Microencapsulation 2012; 29: 380–7
  • Markland P. Emulsions for microencapsulation comprising biodegradable surface-active block copolymers as stabilizers. US Patent Application 20110236496, 2011
  • Matsumoto A, Kitazawa T, Murata J, Horikiri Y, Yamahara H. A novel preparation method for PLGA microspheres using non-halogenated solvents. J Controlled Release 2008; 129: 223–7
  • Meng FT, Ma GH, Qiu W, Su ZG. W/O/W double emulsion technique using ethyl acetate as organic solvent: Effects of its diffusion rate on the characteristics of microparticles. J Controlled Release 2003; 91: 407–16
  • Ramstack JM. Apparatus and method for preparing microparticles using liquid–liquid extraction. US Patent 6471995, 2002
  • Sah H. Microencapsulation techniques using ethyl acetate as a dispersed solvent: Effects of its extraction rate on the characteristics of PLGA microspheres. J Controlled Release 1997; 47: 233–45
  • Sawalha H, Purwanti N, Rinzema A, Schroën K, Boom R. Polylactide microspheres prepared by premix membrane emulsification – Effects of solvent removal rate. J Membr Sci 2008; 310: 484–93
  • Soppimath KS, Aminabhavi TM. Ethyl acetate as a dispersed solvent in the production of poly(D,L-lactide-co-glycolide) microspheres: Effect of process parameters and polymer type. J Microencapsulation 2002; 19: 281–92
  • Suzuki T, Matsukawa Y, Suzuki A. Method for preparing microsphere. US Patent 7323039, 2008
  • Wischke C, Schwendeman SP. Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles. Int J Pharm 2008; 364: 298–327
  • Yang YY, Chia HH, Chung TS. Effect of preparation temperature on the characteristics and release profiles of PLGA microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method. J Controlled Release 2000; 69: 81–96
  • Ye M, Kim S, Park K. Issues in long-term protein delivery using biodegradable microparticles. J Controlled Release 2010; 146: 241–60

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.