Development, characterisation and pharmacoscintigraphic evaluation of nano-fluticasone propionate dry powder inhalation as potential antidote against inhaled toxic gases

References

• Ali R, Jain GK, Iqbal Z, Talegaonkar S, Pandit P, Sule S, Malhotra G, Khar RK, Bhatnagar A, Ahmad FJ. Development and clinical trial of nano-atropine sulfate dry powder inhaler as a novel organophosphorous poisoning antidote. Nanomedicine: NMB 2009; 5: 55–63
   PubMed Web of Science ®Google Scholar
• Baraket M, Oliver BG, Burgess JK, Lim S, King GG, Black JL. Is low dose inhaled corticosteroid therapy as effective for inflammation and remodeling in asthma? A randomized, parallel group study. Respir Res 2012; 13: 1–11
   PubMedGoogle Scholar
• Barrett AM, Adams PJ. Chlorine truck attack consequences and mitigation. Risk Anal 2011; 31: 1243–59
   PubMedGoogle Scholar
• Bei D, Marszalek J, Youan BB. Formulation of dacarbazine-loaded cubosomes-part I: influence of formulation variables. AAPS PharmSciTech 2009; 10: 1032–9
   PubMed Web of Science ®Google Scholar
• Bhavna Ahmad FJ, Mittal G, Jain GK, Malhotra G, Khar RK, Bhatnagar A. Nano-salbutamol dry powder inhalation: A new approach for treating broncho-constrictive conditions. Eur J Pharm Biopharm 2009; 71: 282–91
   PubMed Web of Science ®Google Scholar
• Biddiscombe MF, Meah SN, Underwood SR, Usmani OS. Comparing lung regions of interest in gamma scintigraphy for assessing inhaled therapeutic aerosol deposition. J Aerosol Med Pulm Drug Deliv 2011; 24: 165–73
   PubMed Web of Science ®Google Scholar
• Buscher BA, Jägfeldt H, Sandman H, Brust-van Schaik R, van Schaik F, Brüll LP. The determination of budesonide and fluticasone in human sputum samples collected from COPD patients using LC-MS/MS. J Chromatogr B: Analyt Technol Biomed Life Sci 2012; 880: 6–11
   PubMed Web of Science ®Google Scholar
• Carvalho TC, Carvalho SR, McConville JT. Formulations for pulmonary administration of anticancer agents to treat lung malignancies. J Aerosol Med Pulm Drug Deliv 2011; 24: 61–80
   PubMed Web of Science ®Google Scholar
• Chan HK, Gonda I. Aerodynamic properties of elongated particles of cromoglycic acid. J Aerosol Sci 1989; 20: 157–68
   Web of Science ®Google Scholar
• Cowie RL, Giembycz MA, Leigh R. Mometasone furoate: an inhaled glucocorticoid for the management of asthma in adults and children. Expert Opin Pharmacother 2009; 10: 2009–14
   PubMed Web of Science ®Google Scholar
• Cun D, Jensen DK, Maltesen MJ, Bunker M, Whiteside P, Scurr D, Foged C, Nielsen HM. High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: quality by design optimization and characterization. Eur J Pharm Biopharm 2011; 77: 26–35
   PubMed Web of Science ®Google Scholar
• Davies NM, Feddah MR. A novel method for assessing dissolution of aerosol inhaler products. Int J Pharm 2003; 255: 175–87
   PubMed Web of Science ®Google Scholar
• do Pico GA. Toxic gas inhalation. Curr Opin Pulm Med 1995; 1: 102–8
   PubMedGoogle Scholar
• Fuller R, Johnson M, Bye A. Fluticasone propionate – an update on preclinical and clinical experience. Respir Med 1995; 89(Suppl A)3–18
   PubMedGoogle Scholar
• Gill S, Benberg R, Ku T, Azarmi S, Roa W, Prenner EJ. Nanoparticles: Characteristics, mechanisms of action, and toxicity in pulmonary drug delivery: A review. J Biomed Nanotech 2007; 3: 107–19
   Web of Science ®Google Scholar
• Hess DR. Aerosol delivery devices in the treatment of asthma. Respir Care 2008; 53: 699–723
   PubMed Web of Science ®Google Scholar
• Islam N, Cleary MJ. Developing an efficient and reliable dry powder inhaler for pulmonary drug delivery – a review for multidisciplinary researchers. Med Eng Phys 2012; 34: 409–27
   PubMed Web of Science ®Google Scholar
• Jackson LD, Polygenis D, McIvor RA, Worthington I. Comparative efficacy and safety of inhaled corticosteroids in asthma. Can J Clin Pharmacol 1999; 6: 26–37
   PubMedGoogle Scholar
• Kumar N, Soni S, Jaimini A, Ahmad FJ, Bhatnagar A, Mittal G. Edetate calcium disodium nanoparticle dry powder inhalation: a novel approach against heavy metal decorporation. Int J Pharm 2011; 416: 376–83
   PubMed Web of Science ®Google Scholar
• Larhrib H, Martin GP, Prime D, Marriott C. Characterisation and deposition studies of engineered lactose crystals with potential for use as a carrier for aerosolised salbutamol sulfate from dry powder inhalers. Eur J Pharm Sci 2003; 19: 211–21
   PubMed Web of Science ®Google Scholar
• Lucas P, Anderson K, Staniforth JN. Protein deposition from dry powder inhalers: fine particle multiplets as performance modifiers. Pharm Res 1998; 15: 562–9
   PubMed Web of Science ®Google Scholar
• Makarovsky I, Markel G, Dushnitsky T, Eisenkraft A. Ammonia – when something smells wrong. Isr Med Assoc J 2008; 10: 537–43
   PubMed Web of Science ®Google Scholar
• Mäkelä MJ, Malmberg LP, Csonka P, Klemola T, Kajosaari M, Pelkonen AS. Salmeterol and fluticasone in young children with multiple-trigger wheeze. Ann Allergy Asthma Immunol 2012; 109: 65–70
   PubMedGoogle Scholar
• Mansour HM, Rhee YS, Wu X. Nanomedicine in pulmonary delivery. Int J Nanomedicine 2009; 4: 299–319
   PubMed Web of Science ®Google Scholar
• Melani AS, Nebulized corticosteroids in asthma and COPD: An Italian appraisal. Respir Care, 2012;57(7):1161–74
   Google Scholar
• Mittal G, Singh T, Goomer NC, Bhatnagar A, Lulla A, Malhotra G, Kashyap R, Tripathi RP, Formulations and methods thereof for making radiolabeled dry powder. 2008; Patent No. 1536/DEL/2008
   Google Scholar
• Mohan A, Kumar SN, Rao MH, Bollineni S, Manohar IC. Acute accidental exposure to chlorine gas: Clinical presentation, pulmonary functions and outcomes. Indian J Chest Dis Allied Sci 2010; 52: 149–52
   PubMedGoogle Scholar
• Murnane D, Martin GP, Marriott C. Dry powder formulations for inhalation of fluticasone propionate and salmeterol xinafoate microcrystals. J Pharm Sci 2009; 98: 503–15
   PubMed Web of Science ®Google Scholar
• Nelson HS, Busse WW, de Boisblanc BP, Berger WE, Noonan MJ, Webb DR, Wolford JP, Mahajan PS, Hamedani AG, Shah T, et al. Fluticasone propionate powder: Oral corticosteroidsparing effect and improved lung function and quality of life in patients with severe chronic asthma. J Allergy Clin Immunol 1999; 103: 267–75
   PubMedGoogle Scholar
• Newman SP, Clark AR, Talaee N, Clarke SW. Pressurized aerosol deposition in the human lung with and without an “open” spacer device. Thorax 1989; 44: 706–10
   PubMed Web of Science ®Google Scholar
• Newman SP, Pavia D, Moren F, Sheahan NF, Clarke SW. Deposition of pressurised aerosols in the human respiratory tract. Thorax 1981; 36: 52–5
   PubMed Web of Science ®Google Scholar
• Newman SP, Wilding IR. Gamma scintigraphy: an in vivo technique for assessing the equivalence of inhaled products. Int J Pharm 1998; 170: 1–9
   Google Scholar
• Patton JS, Byron PR. Inhaling medicines: delivering drugs to the body through the lungs. Nat Rev Drug Discov 2007; 6: 67–74
   PubMed Web of Science ®Google Scholar
• Prezant DJ, Levin S, Kelly KJ, Aldrich TK. Upper and lower respiratory diseases after occupational and environmental disasters. Mt Sinai J Med 2008; 75: 89–100
   PubMedGoogle Scholar
• Q3C – Tables and List. In: Guidance for Industry, ICH Guidelines for Impurities: Residual Solvents. 2012; pp. 5–8. Available at: http://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/default.htm. Accessed 12 October 2012
   Google Scholar
• Singh AK, Verma J, Bhatnagar A, Sen S, Bose M. Tc-99m isoniazid: a specific agent for diagnosis of tuberculosis. World J Nucl Med 2003; 2: 292–305
   Google Scholar
• Sultana S, Talegaonkar S, Ali R, Mittal G, Bhatnagar A, Ahmad FJ. Formulation development and optimization of alpha ketoglutarate nanoparticles for cyanide poisoning. Powder Technol 2011; 211: 1–9
   Google Scholar
• Sundblad BM, Larsson BM, Acevedo F, Ernstgard L, Johanson G, Larsson K, Palmberg L. Acute respiratory effects of exposure to ammonia on healthy persons. Scand J Work Environ Health 2004; 30: 313–21
   PubMed Web of Science ®Google Scholar
• Tang P, Chan HK, Raper JA. Prediction of aerodynamic diameter of particles with rough surfaces. Powder Technol 2004; 147: 64–78
   Web of Science ®Google Scholar
• van Grunsven PM, van Schayck CP, Molema J, Akkermans RP, van Weel C. Effect of inhaled corticosteroids on bronchial responsiveness in patients with “corticosteroid naïve” mild asthma: a meta-analysis. Thorax 1999; 54: 316–22
   PubMed Web of Science ®Google Scholar
• White CW, Martin JG. Chlorine gas inhalation: human clinical evidence of toxicity and experience in animal models. Proc Am Thorac Soc 2010; 7: 257–63
   PubMedGoogle Scholar
• Winder C. The toxicology of chlorine. Environ Res 2001; 85: 105–14
   PubMed Web of Science ®Google Scholar