A “drug cocktail” delivered by microspheres for the local treatment of rat glioblastoma

References

• Allhenn D, Lamprecht A. Microsphere preparation using the untoxic solvent glycofurol. Pharm Res 2011; 28: 563–71
   PubMed Web of Science ®Google Scholar
• Arosarena O, Guerin C, Brem H, Laterra J. Endothelial differentiation in intracerebral and subcutaneous experimental gliomas. Brain Res 1994; 640: 98–104
   PubMed Web of Science ®Google Scholar
• Ayalasomayajula SP, Kompella UB. Subconjunctivally administered celecoxib-PLGA microparticles sustain retinal drug levels and alleviate diabetes-induced oxidative stress in a rat model. Eur J Pharmacol 2005; 511: 191–8
   PubMed Web of Science ®Google Scholar
• Ayubk O. Subcutaneous reservoir and pump for sterile access to ventricular cerebrospinal fluid. Lancet 1963; 282: 983–4
   Google Scholar
• Bakhshi S, North RB. Implantable pumps for drug delivery to the brain. J Neurooncol 1995; 26: 133–9
   PubMed Web of Science ®Google Scholar
• Bobo RH, Laske DW, Akbasak A, Morrison PF, Dedrick RL, Oldfield EH. Convection-enhanced delivery of macromolecules in the brain. Proc Natl Acad Sci USA 1994; 91: 2076–80
   PubMed Web of Science ®Google Scholar
• Brem H, Mahaley Jr MS, Jr, Vick NA, Black KL, Schold Jr SC, Jr, Burger PC, Friedman AH, Ciric IS, Eller TW, Cozzens JW, et al. Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas. J Neurosurg 1991; 74: 441–6
   PubMed Web of Science ®Google Scholar
• Dantzig AH, De Alwis DP, Burgess M. Considerations in the design and development of transport inhibitors as adjuncts to drug therapy. Adv Drug Deliv Rev 2003; 55: 133–50
   PubMed Web of Science ®Google Scholar
• Di Paolo A, Bocci G. Drug distribution in tumors: Mechanisms, role in drug resistance, and methods for modification. Curr Oncol Rep 2007; 9: 109–14
   PubMedGoogle Scholar
• Engelhard HH. The role of interstitial BCNU chemotherapy in the treatment of malignant glioma. Surg Neurol 2000; 53: 458–64
   PubMed Web of Science ®Google Scholar
• Garfield J, Dayan AD. Postoperative intracavitary chemotherapy of malignant gliomas. A preliminary study using methotrexate. J Neurosurg 1973; 39: 315–22
   PubMed Web of Science ®Google Scholar
• Groothuis DR. The blood-brain and blood-tumor barriers: A review of strategies for increasing drug delivery. Neuro Oncol 2000; 2: 45–59
   PubMed Web of Science ®Google Scholar
• Guo A, Marinaro W, Hu P, Sinko PJ. Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic anion transporter (cMOAT). Drug Metab Dispos 2002; 30: 457–63
   PubMed Web of Science ®Google Scholar
• Hart MG, Grant R, Garside R, Rogers G, Somerville M, Stein K. Chemotherapy wafers for high grade glioma. Cochrane Database Syst Rev 2011; 3: CD007294
   Google Scholar
• Hassenbusch SJ, Nardone EM, Levin VA, Leeds N, Pietronigro D. Stereotactic injection of DTI-015 into recurrent malignant gliomas: Phase I/II trial. Neoplasia 2003; 5: 9–16
   PubMed Web of Science ®Google Scholar
• Joki T, Heese O, Nikas DC, Bello L, Zhang J, Kraeft SK, Seyfried NT, Abe T, Chen LB, Carroll RS, et al. Expression of cyclooxygenase 2 (COX-2) in human glioma and in vitro inhibition by a specific COX-2 inhibitor, NS-398. Cancer Res 2000; 60: 4926–31
   PubMed Web of Science ®Google Scholar
• Kleihues P, Ohgaki H. Primary and secondary glioblastomas: From concept to clinical diagnosis. Neuro Oncol 1999; 1: 44–51
   PubMedGoogle Scholar
• Lamprecht A, Benoit JP. Etoposide nanocarriers suppress glioma cell growth by intracellular drug delivery and simultaneous P-glycoprotein inhibition. J Control Release 2006; 112: 208–13
   PubMed Web of Science ®Google Scholar
• Li KW, Dang W, Tyler BM, Troiano G, Tihan T, Brem H, Walter KA. Polilactofate microspheres for paclitaxel delivery to central nervous system malignancies. Clin Cancer Res 2003; 9: 3441–7
   PubMed Web of Science ®Google Scholar
• Menei P, Capelle L, Guyotat J, Fuentes S, Assaker R, Bataille B, Francois P, Dorwling-Carter D, Paquis P, Bauchet L, et al. Local and sustained delivery of 5-fluorouracil from biodegradable microspheres for the radiosensitization of malignant glioma: A randomized phase II trial. Neurosurgery 2005; 56: 242–8, ; discussion 242–8
   PubMed Web of Science ®Google Scholar
• Menei P, Jadaud E, Faisant N, Boisdron-Celle M, Michalak S, Fournier D, Delhaye M, Benoit JP. Stereotaxic implantation of 5-fluorouracil-releasing microspheres in malignant glioma. Cancer 2004; 100: 405–10
   PubMed Web of Science ®Google Scholar
• Minchinton AI, Tannock IF. Drug penetration in solid tumours. Nat Rev Cancer 2006; 6: 583–92
   PubMed Web of Science ®Google Scholar
• Padowski JM, Pollack GM. Examination of the ability of the nasal administration route to confer a brain exposure advantage for three chemical inhibitors of P-glycoprotein. J Pharm Sci 2010; 99: 3226–33
   PubMed Web of Science ®Google Scholar
• Pelis RM, Shahidullah M, Ghosh S, Coca-Prados M, Wright SH, Delamere NA. Localization of multidrug resistance-associated protein 2 in the nonpigmented ciliary epithelium of the eye. J Pharmacol Exp Ther 2009; 329: 479–85
   PubMed Web of Science ®Google Scholar
• Rhines LD, Sampath P, Dimeco F, Lawson HC, Tyler BM, Hanes J, Olivi A, Brem H. Local immunotherapy with interleukin-2 delivered from biodegradable polymer microspheres combined with interstitial chemotherapy: A novel treatment for experimental malignant glioma. Neurosurgery 2003; 52: 872–9, ; discussion 879–80
   PubMed Web of Science ®Google Scholar
• Roullin VG, Lemaire L, Venier-Julienne MC, Faisant N, Franconi F, Benoit JP. Release kinetics of 5-fluorouracil-loaded microspheres on an experimental rat glioma. Anticancer Res 2003; 23: 21–5
   PubMed Web of Science ®Google Scholar
• Sanson M, Ameri A, Monjour A, Sahmoud T, Ronchin P, Poisson M, Delattre JY. Treatment of recurrent malignant supratentorial gliomas with ifosfamide, carboplatin and etoposide: A phase II study. Eur J Cancer 1996; 32A: 2229–35
   PubMed Web of Science ®Google Scholar
• Schinkel AH, Wagenaar E, Mol CA, Van Deemter L. P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J Clin Invest 1996; 97: 2517–24
   PubMed Web of Science ®Google Scholar
• Shirazi FH, Bahrami G, Stewart DJ, Tomiak E, Delorme F, Noel D, Goel R. A rapid reversed phase high performance liquid chromatographic method for determination of etoposide (VP-16) in human plasma. J Pharm Biomed Anal 2001; 25: 353–6
   PubMed Web of Science ®Google Scholar
• Shono Y, Jantratid E, Janssen N, Kesisoglou F, Mao Y, Vertzoni M, Reppas C, Dressman JB. Prediction of food effects on the absorption of celecoxib based on biorelevant dissolution testing coupled with physiologically based pharmacokinetic modeling. Eur J Pharm Biopharm 2009; 73: 107–14
   PubMed Web of Science ®Google Scholar
• Siepmann J, Siepmann F. Mathematical modeling of drug delivery. Int J Pharm 2008; 364: 328–43
   PubMed Web of Science ®Google Scholar
• Subbaramaiah K, Dannenberg AJ. Cyclooxygenase 2: A molecular target for cancer prevention and treatment. Trends Pharmacol Sci 2003; 24: 96–102
   PubMed Web of Science ®Google Scholar
• Totzke G, Schulze-Osthoff K, Janicke RU. Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition. Oncogene 2003; 22: 8021–30
   PubMed Web of Science ®Google Scholar
• Tunggal JK, Melo T, Ballinger JR, Tannock IF. The influence of expression of P-glycoprotein on the penetration of anticancer drugs through multicellular layers. Int J Cancer 2000; 86: 101–7
   PubMed Web of Science ®Google Scholar
• Vinchon-Petit S, Jarnet D, Michalak S, Lewis A, Benoit JP, Menei P. Local implantation of doxorubicin drug eluting beads in rat glioma. Int J Pharm 2010; 402: 184–9
   Google Scholar
• Watanabe K, Kanaya H, Fujiyama Y, Kim P. Combination chemotherapy using carboplatin (jm-8) and etoposide (jet therapy) for recurrent malignant gliomas: A phase ii study. Acta Neurochir 2002; 144: 1265–70
   PubMed Web of Science ®Google Scholar